Identification of antiparasitic drug targets using a multi-omics workflow in the acanthocephalan model

CONCLUSIONS: The combination of genomics, transcriptomics, and proteomics led to a broadly applicable procedure for the cost- and time-saving identification of candidate target proteins in parasites. The ligands predicted to bind can now be further evaluated for their suitability in the control of acanthocephalans. The workflow has been deposited at the Galaxy workflow server under the URL tinyurl.com/yx72rda7 .PMID:36180835 | DOI:10.1186/s12864-022-08882-1

Source: Genomics Proteomics ... - September 30, 2022 Category: Genetics & Stem Cells Authors: Hanno Schmidt Katharina Mauer Manuel Glaser Bahram Sayyaf Dezfuli S ören Lukas Hellmann Ana L úcia Silva Gomes Falk Butter Rebecca C Wade Thomas Hankeln Holger Herlyn Source Type: research