Systemic Lupus Erythematosus Risk

Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease. The etiology of SLE is multifactorial and includes potential environmental triggers, which may occur sequentially (the “multi-hit” hypothesis). This review focuses on SLE risk potentially associated with environmental factors including infections, the microbiome, diet, respirable exposures (eg, crystalline silica, smoking, air pollution), organic pollutants, heavy metals, and ultraviolet radiation.

Source: Rheumatic Disease Clinics of North America - September 30, 2022 Category: Rheumatology Authors: Jia Li Liu, Jennifer M.P. Woo, Christine G. Parks, Karen H. Costenbader, S øren Jacobsen, Sasha Bernatsky Source Type: research