Viruses, Vol. 14, Pages 2167: First Genomic Evidence of a Henipa-like Virus in Brazil

Viruses, Vol. 14, Pages 2167: First Genomic Evidence of a Henipa-like Virus in Brazil Viruses doi: 10.3390/v14102167 Authors: Hernández da Paz Silva Silva Barros Nunes Casseb Medeiros Vasconcelos Cruz The viral genus Henipavirus includes two highly virulent zoonotic viruses of serious public health concern. Hendra henipavirus and Nipah henipavirus outbreaks are restricted to Australia and Southeast Asia, respectively. The Henipavirus genus comprises mostly bat-borne viruses, but exceptions have already been described as novel viruses with rodents and shrews as reservoir animals. In the Americas, scarce evidence supports the circulation of these viruses. In this communication, we report a novel henipa-like virus from opossums (Marmosa demerarae) from a forest fragment area in the Peixe-Boi municipality, Brazil, after which the virus was named the Peixe-Boi virus (PBV). The application of next-generation sequencing and metagenomic approach led us to discover the original evidence of a henipa-like virus genome in Brazil and South America and the original description of a henipa-like virus in marsupial species. These findings emphasize the importance of further studies to characterize PBV and clarify its ecology, impact on public health, and its relationship with didelphid marsupials and henipaviruses.
Source: Viruses - Category: Virology Authors: Tags: Communication Source Type: research