Transcatheter Edge-to-Edge Repair (TEER) of Mitral Valve

Transcatheter Edge-to-Edge Repair (TEER) of Mitral Valve Transcatheter Edge-to-Edge Repair (TEER) of the mitral valve is done for treatment of mitral regurgitation [1]. Anterior and posterior leaflets of mitral valve are approximated using a clipping device and is similar to the corresponding surgical procedure known as Alfieri stitch [2]. Earlier porcine study had used left thoracotomy for placing the flexible delivery catheter with a clip in the left atrium. The clip grasped and approximated the mid portion of the anterior and posterior mitral leaflets with echocardiographic and fluoroscopic guidance. Clip was detached from the system and the catheter withdrawn after confirmation of creation of double orifice [3]. EVEREST (Endovascular Valve Edge-to-Edge REpair Study) cohort was a prospective multicenter single arm study to evaluate the feasibility, safety, and efficacy of the MitraClip system [1]. Among the 107 patients treated, 10 had a major adverse event including one nonprocedural death. There was no embolization of the clip in the study. Partial clip detachment occurred in 10 patients. Acute procedural success was achieved in 74% and 64% were discharged with 1+ or lesser mitral regurgitation. 30% had mitral valve surgery 3.2 years after the clip procedures. Surgical repair was successful in 21 of the 25 cases planned. Two thirds of the successfully treated patients were free from death, mitral valve surgery or mitral regurgitation more than 2+ at 12 months. There were...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Angiography and Interventions Structural Heart Disease Interventions Source Type: blogs