The Relation between Plasma Gelsolin Levels and Prognosis in Patients with Acute İschemic Stroke upon Admission to Emergency Department

To compare serum gelsolin levels and Glasgow Coma Scale (GCS) scores in patients with acute ischemic stroke and to compare with healthy control subjects. Included in this study were patients with onset of symptoms in the first 3 h after acute ischemic stroke. Healthy volunteers were included as the control group. Patients with chronic obstructive pulmonary disease, diabetes mellitus, acute coronary syndromes, renal failure, heart failure, trauma, hepatic failure, infection, sepsis, and hematologic and oncologic disease were excluded from study. Venous blood samples were obtained from the patients and the control group upon admission to the emergency department. All patients' GCS scores were determined on admission. Plasma samples were stored at −80°C until evaluation. Patients with stroke were followed up for length of hospital stay, length of intensive care unit stay, and in-hospital mortality. The plasma gelsolin levels were determined by the enzyme-linked immunosorbent assay method. The results of stroke and control groups were compared by Mann-Whitney U Test.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research