Impact of Demographics and Clinical Features on Initial Treatment Pathway for Vestibular Schwannoma

Objective To identify demographic and clinical features impacting initial treatment pathway for vestibular schwannoma. Study Design Retrospective chart review. Setting Tertiary care academic medical center. Patients Patients diagnosed with vestibular schwannoma between 2009 and 2019. Interventions Observation, stereotactic radiosurgery, or microsurgical resection. Main Outcome Measures χ2 Test, one-way analysis of variance, and multivariate logistic regression were used to correlate demographic and clinical factors with initial treatment pathway for 197 newly diagnosed vestibular schwannoma patients. Results Among 197 patients, 93 (47%) were initially treated with observation, 60 (30%) with stereotactic radiation (Gamma Knife) and 44 (22%) with surgical resection. Age univariately had no statistically significant impact on initial pathway, but those undergoing surgery trended toward a younger demographic (49.1 yr [surgery] versus 57.2 yr [observation] versus 59.0 yr [Gamma Knife]). Men were more likely to be initially observed than women (p = 0.04). Patients initially observed were more likely to have a lower Koos classification (p
Source: Otology and Neurotology - Category: ENT & OMF Tags: TUMORS OF THE EAR AND CRANIAL BASE Source Type: research