Perinatalis stroke: vizsg álati irányelv

Orv Hetil. 2022 Jun 12;163(24):952-960. doi: 10.1556/650.2022.32472. Print 2022 Jun 12.ABSTRACTPerinatal stroke encompasses a heterogenous group of neurological syndromes due to cerebrovascular diseases, leading to chronic neurological sequelae in most of the cases. Based on pathophysiology, strokes are classified as perinatal arterial ischemic stroke, cerebral sinovenous thrombosis and perinatal haemorrhagic stroke. If not recognized in the neonatal period, the condition usually presents with focal asymmetry between 4-8 months of age and is referred to as presumed perinatal stroke. Nowadays, the increased utilization of magnetic resonance (MR) imaging has resulted in the establishment of an earlier and more accurate diagnosis. The overall incidence of perinatal stroke is ~1 in 1100 live births. Even though neonates with stroke develop normally in 40% of the cases, most patients develop long-term neurological sequalae presenting as cerebral palsy, epilepsy, cognitive impairment, behavioural problems, language delay, visual field defect, hearing loss or a combination of these symptoms. To better understand the condition and predict the outcome, several studies have analysed the associations among risk factors, MR findings and outcome. In this review, we summarize the epidemiology, the imaging modalities, the clinical presentation, and the recommended management strategies as well as the available data on long-term neurodevelopmental outcome. We have also included our proposed ...
Source: Orvosi Hetilap - Category: General Medicine Authors: Source Type: research