Assessment of dengue virus inactivation in random donor platelets using amotosalen and ultraviolet A illumination

CONCLUSIONS: Amotosalen/UVA pathogen inactivation treatment showed efficient inactivation of DENV in platelet components. Therefore, it seems to be a promising method for mitigating the risk of dengue transmission through transfusion of potentially contaminated platelet components in dengue-endemic countries such as India.

Source: Asian Journal of Transfusion Science - July 30, 2022 Category: Hematology Authors: Ankit Kumar Aseem Kumar Tiwari Satendra Kumar Ashutosh Biswas Gurpreet Singh Kabita Chatterjee Sourit Chakroborty Sujatha Sunil Source Type: research