Favorable Survival After Screening for Young-Onset Colorectal Cancer: Benefits of Screening in Young Adults

This study evaluated data from a colorectal cancer registry and medical records at a tertiary Japanese cancer center. PATIENTS: All patients with colorectal cancer who were registered at a Japanese tertiary cancer center between January 2007 and December 2016 were included. MAIN OUTCOME MEASURES: The colorectal cancer cases were categorized as screening-detected colorectal cancer and non–screening-detected colorectal cancer, and patients were categorized into 3 age groups: 75 years. The baseline characteristics and survival outcomes of the groups were compared using Cox regression models. RESULTS: A total of 4345 patients were identified, with a median follow-up of 4.6 years. Relative to 50- to 75-year-old individuals, young-onset colorectal cancer was linked to a higher proportion of rectal cancer (50.4% vs 43.3%), a lower proportion of screening-detected colorectal cancer (29.4% vs 35.8%), a lower proportion of stage I colorectal cancer (15.2% vs 30.3%), and a higher proportion of stage III to IV colorectal cancer (64.0% vs 49.4%). Among patients who were
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions: Colorectal Cancer Source Type: research