Benefits of esmolol in adults with sepsis and septic shock: An updated meta-analysis of randomized controlled trials

Conclusions: Esmolol treatment may be safe and effective in decreasing 28-day mortality, controlling heart rate, and providing cardioprotective function, but has no effect on lung injury in patients with sepsis or septic shock after early fluid resuscitation. Improvement in cardiac function may be related to changes in serum inflammatory mediators. No significant adverse effects on tissue perfusion and oxygen utilization were observed.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news