Myelin oligodendrocyte glycoprotein-IgG1 associated disorders (MOGAD) following SARS-CoV-2 infection: A case series

This case series describes 9 patients diagnosed with myelin oligodendrocyte glycoprotein (MOG)-IgG1 associated disorder (MOGAD) following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Patients developed neurological symptoms between 4  days and 3 weeks following SARS-CoV-2 infection. Myelitis was observed in 4 patients; 4 presented with optic neuritis; and encephalopathy was observed in 3. Serum MOG-IgG cell-based assay was positive in each case. Most patients had near-complete recovery following acute immunosuppression.

Source: Journal of Neuroimmunology - July 13, 2022 Category: Allergy & Immunology Authors: Jeffrey Lambe, Marisa P. McGinley, Brandon P. Moss, Yang Mao-Draayer, Roman Kassa, John R. Ciotti, Sara Mariotto, Amy Kunchok Tags: Short Communication Source Type: research