VDR promotes nucleus pulposus cell mitophagy as a protective mechanism against oxidative stress injury

This study demonstrates that VDR activation ameliorates oxidative damage and decreases NP cell apoptosis by promoting PINK1/Parkin-dependent mitophagy, indicating that VDR may serve as a promising therapeutic target in the management of IDD.PMID:35786375 | DOI:10.1080/10715762.2022.2094791
Source: Free Radical Research - Category: Research Authors: Source Type: research