The Combination of Salidroside and Hedysari Radix Polysaccharide Inhibits Mitochondrial Damage and Apoptosis via the PKC/ERK Pathway

CONCLUSIONS: CSH treatment have protective effects against Aβ 25-35-induced cytotoxicity through decreasing ROS levels, increasing MMP, inhibiting early apoptosis, and regulating PKC/ERK pathway in HT22 cells. CSH may be a potential therapeutic agent for treating or preventing neurodegenerative diseases.PMID:35795284 | PMC:PMC9252633 | DOI:10.1155/2022/9475703

Source: Evidence-based Complementary and Alternative Medicine - July 7, 2022 Category: Complementary Medicine Authors: Sixia Yang Linshuang Wang Zeping Xie Yi Zeng Qiaowu Xiong Tingting Pei Dongfeng Wei Weidong Cheng Source Type: research