Investigation on the potential targets of Astragaloside IV against intracerebral hemorrhage based on network pharmacology and experimental validation

This study demonstrated that AS-IV could play a critical role on hematoma absorption after ICH by regulating the PI3K/AKT signaling pathway and promoting CD36 phagocytosis, which provided a new thought for the drug development of ICH.PMID:35728292 | DOI:10.1016/j.bioorg.2022.105975

Source: Bioorganic Chemistry - June 21, 2022 Category: Chemistry Authors: Yingyi Zheng Ruoqi Li Yuan Zhou Shanshan Zhang Xiang Fan Source Type: research