Effects of 8-week high-intensity interval training and continuous aerobic training on asprosin secretion and fibrillin-1 gene expression levels in diabetic male rats

ConclusionsIt seems that diabetes has significant effects on increasing asprosin and FBN1 gene expression levels, while HIIT and CAT workouts have significant effects on decreasing asprosin and FBN1 gene expression levels. Therefore, both HIIT and CAT protocols can be utilized as significantly effective strategies for decreasing the levels of asprosin and its upstream gene, i.e., FBN1; thus, a combination of both strategies can be regarded as a useful intervention method for treating diabetes.
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research