Neurodevelopmental outcomes of preterm infants after randomisation to initial resuscitation with lower (FiO2 0.6) initial oxygen levels. An individual patient meta-analysis

Conclusion
Initial FiO2 was not associated with difference in risk of disability/death at 2 years in infants <32 weeks’ gestation but CIs were wide. Substantial benefit or harm cannot be excluded. Larger randomised studies accounting for patient differences, for example, gestation and gender are urgently needed.

Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - June 17, 2022 Category: Perinatology & Neonatology Authors: Oei, J. L., Kapadia, V., Rabi, Y., Saugstad, O. D., Rook, D., Vermeulen, M. J., Boronat, N., Thamrin, V., Tarnow-Mordi, W., Smyth, J., Wright, I. M., Lui, K., van Goudoever, J. B., Gebski, V., Vento, M. Tags: Original research Source Type: research