Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice

Parkinson ’s disease, the second most common neurodegenerative disorder, is characterized by the loss of nigrostriatal dopamine neurons. FBXO7 (F-box protein only 7) (PARK15) mutations cause early-onset Parkinson’...

Source: Molecular Brain - June 14, 2022 Category: Neuroscience Authors: Sachiko Noda, Shigeto Sato, Takahiro Fukuda, Shinichi Ueno, Norihiro Tada and Nobutaka Hattori Tags: Micro report Source Type: research