Amnestic aphasia in MELAS can be epileptogenic

Referring to the article by Sakata et al. we disagree with the diagnosis “thalamic aphasia” [1]. Since thalamic lesions can be associated with status epilepticus (SE) [2], it is crucial that SE has been ruled out2. Therefore, we should know if creatine-kinase (CK) was elevated to 5883 U/l due to myopathy, the stroke-like lesion (SLL), cardiomyopathy, or a SE. Becaus e periodic lateralised epileptiform discharges (PLEDs) can be the manifestation of a non-convulsive/minimal convulsive SE [3], we should know if a SE was recorded on electroencephalography (EEG) on hospital-day 8 and why midazolam was administered.
Source: Brain and Development - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research