Plain Language Summary Publication: Regulation of headache response and transcriptomic network by the trigeminal ganglion clock
Headache. 2024 Apr 24. doi: 10.1111/head.14718. Online ahead of print.NO ABSTRACTPMID:38659307 | DOI:10.1111/head.14718 (Source: Headache)
Source: Headache - April 25, 2024 Category: Neurology Authors: Chorong Han Seung-Hee Yoo Mark J Burish Source Type: research
Blood serum levels of PACAP and migraine onset: A systematic review and meta-analysis of observational studies
CONCLUSION: There is a very low certainty of evidence suggesting that the PACAP level is negatively correlated with migraine disease duration of adults with migraine and it varies greatly among different periods of migraine of both adults and children with migraine.PMID:38659322 | DOI:10.1111/head.14711 (Source: Headache)
Source: Headache - April 25, 2024 Category: Neurology Authors: Guoliang Zhu Miao Wang Fanyi Kong Source Type: research
Implications of high homocysteine levels in migraine pain: An experimental study of the excitability of peripheral meningeal afferents in rats with hyperhomocysteinemia
CONCLUSIONS: Our results demonstrated higher excitability of the trigeminal system of rats with hyperhomocysteinemia. Together with our previous finding about the lower threshold of generation of cortical spreading depression in rats with hyperhomocysteinemia, the present data provide evidence of homocysteine as a factor that increases the sensitivity of the peripheral migraine mechanisms, and the control of homocysteine level may be an important strategy for reducing the risk and/or severity of migraine headache attacks.PMID:38650105 | DOI:10.1111/head.14710 (Source: Headache)
Source: Headache - April 23, 2024 Category: Neurology Authors: Elizaveta Ermakova Kseniia Shaidullova Oleg Gafurov Alsu Kabirova Dinara Nurmieva Guzel Sitdikova Source Type: research
Reliability, validity, and responsiveness of the Arabic version of HIT-6 questionnaire in patients with migraine indicated for preventive therapy: A multi-center study
CONCLUSION: The Arabic version of HIT-6 is valid, reliable, and sensitive to detect clinical changes following migraine prophylactic treatment with a MIC of 4.5 points.PMID:38651363 | DOI:10.1111/head.14719 (Source: Headache)
Source: Headache - April 23, 2024 Category: Neurology Authors: Mona Hussein Amr Hassan Mona A F Nada Zeinab Mohammed Nawal F Abdel Ghaffar Hanaa Kedah Wael Fathy Rehab Magdy Source Type: research
Implications of high homocysteine levels in migraine pain: An experimental study of the excitability of peripheral meningeal afferents in rats with hyperhomocysteinemia
CONCLUSIONS: Our results demonstrated higher excitability of the trigeminal system of rats with hyperhomocysteinemia. Together with our previous finding about the lower threshold of generation of cortical spreading depression in rats with hyperhomocysteinemia, the present data provide evidence of homocysteine as a factor that increases the sensitivity of the peripheral migraine mechanisms, and the control of homocysteine level may be an important strategy for reducing the risk and/or severity of migraine headache attacks.PMID:38650105 | DOI:10.1111/head.14710 (Source: Headache)
Source: Headache - April 23, 2024 Category: Neurology Authors: Elizaveta Ermakova Kseniia Shaidullova Oleg Gafurov Alsu Kabirova Dinara Nurmieva Guzel Sitdikova Source Type: research
Reliability, validity, and responsiveness of the Arabic version of HIT-6 questionnaire in patients with migraine indicated for preventive therapy: A multi-center study
CONCLUSION: The Arabic version of HIT-6 is valid, reliable, and sensitive to detect clinical changes following migraine prophylactic treatment with a MIC of 4.5 points.PMID:38651363 | DOI:10.1111/head.14719 (Source: Headache)
Source: Headache - April 23, 2024 Category: Neurology Authors: Mona Hussein Amr Hassan Mona A F Nada Zeinab Mohammed Nawal F Abdel Ghaffar Hanaa Kedah Wael Fathy Rehab Magdy Source Type: research
Association between migraine and exclusive breastfeeding: A cross-sectional study
CONCLUSION: Females with migraine exclusively breastfeed their infants for a shorter duration compared to females without migraine, suggesting the need to better support this population through education on the safety and benefits of exclusive breastfeeding and better access to safe and effective treatment of migraine in lactating females.PMID:38644657 | DOI:10.1111/head.14713 (Source: Headache)
Source: Headache - April 22, 2024 Category: Neurology Authors: Manav V Vyas Nathan Lee Christine Lay Source Type: research
The effectiveness of parenteral agents for pain reduction in patients with migraine presenting to emergency settings: A systematic review and network analysis
CONCLUSIONS: Various parenteral agents were found to provide effective pain relief. Considering the consistent improvements across various outcomes, combination therapy, as well as monotherapy of either metoclopramide or neuroleptics are recommended as first-line options for managing acute migraine pain. There are risks of adverse events, especially akathisia, following treatment with these agents. We recommend that a shared decision-making model be considered to effectively identify the best treatment option based on the patient's needs.PMID:38644702 | DOI:10.1111/head.14704 (Source: Headache)
Source: Headache - April 22, 2024 Category: Neurology Authors: Scott W Kirkland Lloyd Visser Jillian Meyer Daniela R Junqueira Sandra Campbell Cristina Villa-Roel Benjamin W Friedman Nana Owusu Essel Brian H Rowe Source Type: research
Challenges in the management of new daily persistent headache at a tertiary headache center-A retrospective real-world evidence study
CONCLUSION: In this study we add real-world evidence to suggest that prophylactic drugs conventionally used for treating chronic migraine and chronic tension-type headache have limited utility for treating NDPH; however, a partial response in 26% of patients using candesartan and 15% of patients using mirtazapine warrants further investigation in randomized double-blinded placebo-controlled trials.PMID:38646979 | DOI:10.1111/head.14715 (Source: Headache)
Source: Headache - April 22, 2024 Category: Neurology Authors: Thor Linnet Marwa Hussein Henrik Winther Schytz Lars Bendtsen Faisal Mohammad Amin Source Type: research
Nonspecific oral medications versus anti-calcitonin gene-related peptide monoclonal antibodies for migraine: A systematic review and meta-analysis of randomized controlled trials
CONCLUSIONS: There is high certainty that CGRP mAbs are more effective than placebo, but the effect size is small. When feasible, CGRP mAbs may be prescribed as first-line preventives; topiramate or divalproex could be as effective but are less well tolerated. The findings of this study support the recently published 2024 position of the American Headache Society on the use of CGRP mAbs as the first-line treatment.PMID:38634515 | DOI:10.1111/head.14693 (Source: Headache)
Source: Headache - April 18, 2024 Category: Neurology Authors: Jennifer Robblee Sameh M Hakim John M Reynolds Teshamae S Monteith Niushen Zhang Meredith Barad Source Type: research
Depression and anxiety are not associated with migraine outcomes in children and adolescents
Headache. 2024 Apr;64(4):331-332. doi: 10.1111/head.14700. Epub 2024 Apr 18.NO ABSTRACTPMID:38634622 | DOI:10.1111/head.14700 (Source: Headache)
Source: Headache - April 18, 2024 Category: Neurology Authors: Amy A Gelfand Source Type: research
Factors to predict recurrence after epidural blood patch in patients with spontaneous intracranial hypotension
CONCLUSION: Our study suggests that volumetric analysis of intracranial structures may aid in predicting recurrence after EBP treatment in patients with SIH.PMID:38634709 | DOI:10.1111/head.14703 (Source: Headache)
Source: Headache - April 18, 2024 Category: Neurology Authors: Seung Hyun Lee Jooyoung Lee Da-Woon Kim Dong Hyun Kim Sung Jae Ahn Moon Gwan Choi Sungyang Jo Chong Hyun Suh Sun J Chung Source Type: research
Progressive superficial siderosis despite complete remission of intracranial hypotension symptoms following epidural patching: Case report
We report a case of a patient with SIH from a ventral spinal CSF leak that was treated with epidural patching and experienced complete resolution of SIH. Four years later SIH symptoms recurred, and brain magnetic resonance imaging unexpectedly showed the interval accumulation of hemosiderin pigmentation on the cerebellum and brainstem during the period when the patient was without symptoms of SIH. This case uniquely demonstrates the progression of superficial siderosis despite the apparent resolution of SIH. Our findings suggest two divergent pathophysiological outcomes from spinal ventral dural tear: (1) CSF loss causing ...
Source: Headache - April 13, 2024 Category: Neurology Authors: Ian Carroll Wouter Schievink Source Type: research
Progressive superficial siderosis despite complete remission of intracranial hypotension symptoms following epidural patching: Case report
We report a case of a patient with SIH from a ventral spinal CSF leak that was treated with epidural patching and experienced complete resolution of SIH. Four years later SIH symptoms recurred, and brain magnetic resonance imaging unexpectedly showed the interval accumulation of hemosiderin pigmentation on the cerebellum and brainstem during the period when the patient was without symptoms of SIH. This case uniquely demonstrates the progression of superficial siderosis despite the apparent resolution of SIH. Our findings suggest two divergent pathophysiological outcomes from spinal ventral dural tear: (1) CSF loss causing ...
Source: Headache - April 13, 2024 Category: Neurology Authors: Ian Carroll Wouter Schievink Source Type: research
Progressive superficial siderosis despite complete remission of intracranial hypotension symptoms following epidural patching: Case report
We report a case of a patient with SIH from a ventral spinal CSF leak that was treated with epidural patching and experienced complete resolution of SIH. Four years later SIH symptoms recurred, and brain magnetic resonance imaging unexpectedly showed the interval accumulation of hemosiderin pigmentation on the cerebellum and brainstem during the period when the patient was without symptoms of SIH. This case uniquely demonstrates the progression of superficial siderosis despite the apparent resolution of SIH. Our findings suggest two divergent pathophysiological outcomes from spinal ventral dural tear: (1) CSF loss causing ...
Source: Headache - April 13, 2024 Category: Neurology Authors: Ian Carroll Wouter Schievink Source Type: research
