Biomarkers in cluster headache: A systematic review
CONCLUSION: Biomarker findings have been inconsistent and widely non-specific for cluster headache, which explains why none of the previous studies succeeded in identifying a unique biomarker for cluster headache, but instead contributed to substantiating the underlying pathophysiologic mechanisms. Several of the examined biomarkers could hold promise as markers for disease activity but are unfit for a clear distinction from both controls and other headaches.PMID:38111226 | DOI:10.1111/head.14641 (Source: Headache)
Source: Headache - December 19, 2023 Category: Neurology Authors: Marie-Louise K S øborg Rigmor H Jensen Mads Barloese Anja S Petersen Source Type: research
Biomarkers in cluster headache: A systematic review
CONCLUSION: Biomarker findings have been inconsistent and widely non-specific for cluster headache, which explains why none of the previous studies succeeded in identifying a unique biomarker for cluster headache, but instead contributed to substantiating the underlying pathophysiologic mechanisms. Several of the examined biomarkers could hold promise as markers for disease activity but are unfit for a clear distinction from both controls and other headaches.PMID:38111226 | DOI:10.1111/head.14641 (Source: Headache)
Source: Headache - December 19, 2023 Category: Neurology Authors: Marie-Louise K S øborg Rigmor H Jensen Mads Barloese Anja S Petersen Source Type: research
Biomarkers in cluster headache: A systematic review
CONCLUSION: Biomarker findings have been inconsistent and widely non-specific for cluster headache, which explains why none of the previous studies succeeded in identifying a unique biomarker for cluster headache, but instead contributed to substantiating the underlying pathophysiologic mechanisms. Several of the examined biomarkers could hold promise as markers for disease activity but are unfit for a clear distinction from both controls and other headaches.PMID:38111226 | DOI:10.1111/head.14641 (Source: Headache)
Source: Headache - December 19, 2023 Category: Neurology Authors: Marie-Louise K S øborg Rigmor H Jensen Mads Barloese Anja S Petersen Source Type: research
Biomarkers in cluster headache: A systematic review
CONCLUSION: Biomarker findings have been inconsistent and widely non-specific for cluster headache, which explains why none of the previous studies succeeded in identifying a unique biomarker for cluster headache, but instead contributed to substantiating the underlying pathophysiologic mechanisms. Several of the examined biomarkers could hold promise as markers for disease activity but are unfit for a clear distinction from both controls and other headaches.PMID:38111226 | DOI:10.1111/head.14641 (Source: Headache)
Source: Headache - December 19, 2023 Category: Neurology Authors: Marie-Louise K S øborg Rigmor H Jensen Mads Barloese Anja S Petersen Source Type: research
Biomarkers in cluster headache: A systematic review
CONCLUSION: Biomarker findings have been inconsistent and widely non-specific for cluster headache, which explains why none of the previous studies succeeded in identifying a unique biomarker for cluster headache, but instead contributed to substantiating the underlying pathophysiologic mechanisms. Several of the examined biomarkers could hold promise as markers for disease activity but are unfit for a clear distinction from both controls and other headaches.PMID:38111226 | DOI:10.1111/head.14641 (Source: Headache)
Source: Headache - December 19, 2023 Category: Neurology Authors: Marie-Louise K S øborg Rigmor H Jensen Mads Barloese Anja S Petersen Source Type: research
Biomarkers in cluster headache: A systematic review
CONCLUSION: Biomarker findings have been inconsistent and widely non-specific for cluster headache, which explains why none of the previous studies succeeded in identifying a unique biomarker for cluster headache, but instead contributed to substantiating the underlying pathophysiologic mechanisms. Several of the examined biomarkers could hold promise as markers for disease activity but are unfit for a clear distinction from both controls and other headaches.PMID:38111226 | DOI:10.1111/head.14641 (Source: Headache)
Source: Headache - December 19, 2023 Category: Neurology Authors: Marie-Louise K S øborg Rigmor H Jensen Mads Barloese Anja S Petersen Source Type: research
Rural disparities in emergency department utilization for migraine care
CONCLUSION: This study suggests rural populations, particularly in Appalachia, may experience significantly higher ED utilization for migraine compared to nonrural patients. Moreover, rural populations were more likely to receive suboptimal migraine management with opioid analgesia. Multimodal health-care interventions should be developed to improve access to outpatient migraine care and further investigate potential risk factors in the rural population. With high ED utilization, the Appalachian population may benefit most from such an intervention.PMID:38087895 | DOI:10.1111/head.14659 (Source: Headache)
Source: Headache - December 13, 2023 Category: Neurology Authors: Christian Rhudy Aric Schadler Mark Huffmyer Lindsey Porter Source Type: research
Rural disparities in emergency department utilization for migraine care
CONCLUSION: This study suggests rural populations, particularly in Appalachia, may experience significantly higher ED utilization for migraine compared to nonrural patients. Moreover, rural populations were more likely to receive suboptimal migraine management with opioid analgesia. Multimodal health-care interventions should be developed to improve access to outpatient migraine care and further investigate potential risk factors in the rural population. With high ED utilization, the Appalachian population may benefit most from such an intervention.PMID:38087895 | DOI:10.1111/head.14659 (Source: Headache)
Source: Headache - December 13, 2023 Category: Neurology Authors: Christian Rhudy Aric Schadler Mark Huffmyer Lindsey Porter Source Type: research
Rural disparities in emergency department utilization for migraine care
CONCLUSION: This study suggests rural populations, particularly in Appalachia, may experience significantly higher ED utilization for migraine compared to nonrural patients. Moreover, rural populations were more likely to receive suboptimal migraine management with opioid analgesia. Multimodal health-care interventions should be developed to improve access to outpatient migraine care and further investigate potential risk factors in the rural population. With high ED utilization, the Appalachian population may benefit most from such an intervention.PMID:38087895 | DOI:10.1111/head.14659 (Source: Headache)
Source: Headache - December 13, 2023 Category: Neurology Authors: Christian Rhudy Aric Schadler Mark Huffmyer Lindsey Porter Source Type: research
Rural disparities in emergency department utilization for migraine care
CONCLUSION: This study suggests rural populations, particularly in Appalachia, may experience significantly higher ED utilization for migraine compared to nonrural patients. Moreover, rural populations were more likely to receive suboptimal migraine management with opioid analgesia. Multimodal health-care interventions should be developed to improve access to outpatient migraine care and further investigate potential risk factors in the rural population. With high ED utilization, the Appalachian population may benefit most from such an intervention.PMID:38087895 | DOI:10.1111/head.14659 (Source: Headache)
Source: Headache - December 13, 2023 Category: Neurology Authors: Christian Rhudy Aric Schadler Mark Huffmyer Lindsey Porter Source Type: research
Rural disparities in emergency department utilization for migraine care
CONCLUSION: This study suggests rural populations, particularly in Appalachia, may experience significantly higher ED utilization for migraine compared to nonrural patients. Moreover, rural populations were more likely to receive suboptimal migraine management with opioid analgesia. Multimodal health-care interventions should be developed to improve access to outpatient migraine care and further investigate potential risk factors in the rural population. With high ED utilization, the Appalachian population may benefit most from such an intervention.PMID:38087895 | DOI:10.1111/head.14659 (Source: Headache)
Source: Headache - December 13, 2023 Category: Neurology Authors: Christian Rhudy Aric Schadler Mark Huffmyer Lindsey Porter Source Type: research
Rural disparities in emergency department utilization for migraine care
CONCLUSION: This study suggests rural populations, particularly in Appalachia, may experience significantly higher ED utilization for migraine compared to nonrural patients. Moreover, rural populations were more likely to receive suboptimal migraine management with opioid analgesia. Multimodal health-care interventions should be developed to improve access to outpatient migraine care and further investigate potential risk factors in the rural population. With high ED utilization, the Appalachian population may benefit most from such an intervention.PMID:38087895 | DOI:10.1111/head.14659 (Source: Headache)
Source: Headache - December 13, 2023 Category: Neurology Authors: Christian Rhudy Aric Schadler Mark Huffmyer Lindsey Porter Source Type: research
Characteristics associated with response to subcutaneously administered anti-CGRP monoclonal antibody medications in a real-world community cohort of persons living with migraine: A retrospective clinical and genetic study
CONCLUSIONS: In this real-world setting, anti-CGRP preventives reduced MDM persistently and had similar and large effect sizes on MDM reduction; however, clinical and genetic factors influenced response.PMID:38071464 | DOI:10.1111/head.14655 (Source: Headache)
Source: Headache - December 10, 2023 Category: Neurology Authors: Bruce A Chase Irene Semenov Susan Rubin Steven Meyers Angela Mark Thomas Makhlouf Tanya T Chirayil Demetrius Maraganore Jun Wei Siqun L Zheng Jianfeng Xu Alexander Epshteyn Anna Pham Roberta Frigerio Katerina Markopoulou Source Type: research
Characteristics associated with response to subcutaneously administered anti-CGRP monoclonal antibody medications in a real-world community cohort of persons living with migraine: A retrospective clinical and genetic study
CONCLUSIONS: In this real-world setting, anti-CGRP preventives reduced MDM persistently and had similar and large effect sizes on MDM reduction; however, clinical and genetic factors influenced response.PMID:38071464 | DOI:10.1111/head.14655 (Source: Headache)
Source: Headache - December 10, 2023 Category: Neurology Authors: Bruce A Chase Irene Semenov Susan Rubin Steven Meyers Angela Mark Thomas Makhlouf Tanya T Chirayil Demetrius Maraganore Jun Wei Siqun L Zheng Jianfeng Xu Alexander Epshteyn Anna Pham Roberta Frigerio Katerina Markopoulou Source Type: research
Characteristics associated with response to subcutaneously administered anti-CGRP monoclonal antibody medications in a real-world community cohort of persons living with migraine: A retrospective clinical and genetic study
CONCLUSIONS: In this real-world setting, anti-CGRP preventives reduced MDM persistently and had similar and large effect sizes on MDM reduction; however, clinical and genetic factors influenced response.PMID:38071464 | DOI:10.1111/head.14655 (Source: Headache)
Source: Headache - December 10, 2023 Category: Neurology Authors: Bruce A Chase Irene Semenov Susan Rubin Steven Meyers Angela Mark Thomas Makhlouf Tanya T Chirayil Demetrius Maraganore Jun Wei Siqun L Zheng Jianfeng Xu Alexander Epshteyn Anna Pham Roberta Frigerio Katerina Markopoulou Source Type: research
