Migraine and air pollution: A systematic review
CONCLUSIONS: Balancing the generally strong methodologies with the small number of studies, point estimates were mainly above 1.00 for associations of carbon monoxide, nitrogen dioxide, ozone, and particulate matter with migraine. These results were most consistent for nitrogen dioxide.PMID:37795754 | DOI:10.1111/head.14632 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Andrea E Portt Christa Orchard Hong Chen Erjia Ge Christine Lay Peter M Smith Source Type: research

Effects of caffeine on intracranial pressure and pain perception in freely moving rats
CONCLUSIONS: This study demonstrates that caffeine has a lowering effect on ICP as an acute treatment. Interestingly, caffeine acutely caused an increased response in cephalic thresholds supporting hypoalgesic effects. Future studies investigating the beneficial effects of caffeine for elevated ICP are warranted.PMID:37796087 | DOI:10.1111/head.14634 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Ida Marchen Egerod Israelsen Connar Stanley James Westgate Christina Kamp-Jensen Rigmor H Jensen Sajedeh Eftekhari Source Type: research

Plasma calcitonin gene-related peptide and nerve growth factor as headache and pain biomarkers in recently deployed soldiers with and without a recent concussion
CONCLUSION: In this exploratory study, plasma levels of NGF and CGRP showed promise as biomarkers for headache and other types of pain. These findings need to be replicated in other cohorts.PMID:37796114 | DOI:10.1111/head.14635 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Ann I Scher James S McGinley Lyndsey R VanDam Amanda M Campbell Xiyun Chai Billy Collins Scott A Klimp Alan G Finkel Karen Schwab Richard B Lipton Kirk W Johnson Source Type: research

Headache and psychological variables as predictors of disability in individuals with primary headache disorders
CONCLUSION: Psychiatric and transdiagnostic factors contribute uniquely to headache-related functional impairment, which may be important for expanding targeted assessment and behavioral interventions.PMID:37795575 | DOI:10.1111/head.14633 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Halle T McCracken Aaron A Lee Todd A Smitherman Source Type: research

The 2023 Scottsdale Headache Symposium
Headache. 2023 Oct 5. doi: 10.1111/head.14637. Online ahead of print.NO ABSTRACTPMID:37795652 | DOI:10.1111/head.14637 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Deborah I Friedman Rashmi B Halker Singh Scott W Powers Source Type: research

Impact of monthly headache days on migraine-related quality of life: Results from the Chronic Migraine Epidemiology and Outcomes (CaMEO) study
CONCLUSIONS: Increased MHD values were associated with lower MSQ scores; the impact of MHDs on the MSQ domain scores was partially mediated by the presence of depression, anxiety, and allodynia. MHDs remain the predominant driver of the MSQ variation; moreover, most of the variation in the MSQ remains unexplained by the variables we analyzed. Future longitudinal analyses and studies may help clarify the contribution of MHDs, comorbidities, and other factors to changes in HRQoL.PMID:37795746 | DOI:10.1111/head.14629 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Richard B Lipton Patricia Pozo-Rosich Serena L Orr Michael L Reed Kristina M Fanning Brett Dabruzzo Dawn C Buse Source Type: research

Migraine and air pollution: A systematic review
CONCLUSIONS: Balancing the generally strong methodologies with the small number of studies, point estimates were mainly above 1.00 for associations of carbon monoxide, nitrogen dioxide, ozone, and particulate matter with migraine. These results were most consistent for nitrogen dioxide.PMID:37795754 | DOI:10.1111/head.14632 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Andrea E Portt Christa Orchard Hong Chen Erjia Ge Christine Lay Peter M Smith Source Type: research

Effects of caffeine on intracranial pressure and pain perception in freely moving rats
CONCLUSIONS: This study demonstrates that caffeine has a lowering effect on ICP as an acute treatment. Interestingly, caffeine acutely caused an increased response in cephalic thresholds supporting hypoalgesic effects. Future studies investigating the beneficial effects of caffeine for elevated ICP are warranted.PMID:37796087 | DOI:10.1111/head.14634 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Ida Marchen Egerod Israelsen Connar Stanley James Westgate Christina Kamp-Jensen Rigmor H Jensen Sajedeh Eftekhari Source Type: research

Plasma calcitonin gene-related peptide and nerve growth factor as headache and pain biomarkers in recently deployed soldiers with and without a recent concussion
CONCLUSION: In this exploratory study, plasma levels of NGF and CGRP showed promise as biomarkers for headache and other types of pain. These findings need to be replicated in other cohorts.PMID:37796114 | DOI:10.1111/head.14635 (Source: Headache)
Source: Headache - October 5, 2023 Category: Neurology Authors: Ann I Scher James S McGinley Lyndsey R VanDam Amanda M Campbell Xiyun Chai Billy Collins Scott A Klimp Alan G Finkel Karen Schwab Richard B Lipton Kirk W Johnson Source Type: research

Safety, tolerability, and effectiveness of repetitive intravenous dihydroergotamine for refractory chronic migraine with cardiovascular risk factors: A retrospective study
CONCLUSION: Patients receiving intravenous DHE by the Jefferson Headache Center inpatient headache protocol had significantly reduced pain severity at discharge. No clinically significant cardiac or electrocardiogram abnormalities were detected in patients with elevated (or low) atherosclerotic cardiovascular disease risk. Repetitive intravenous DHE used by our protocol was safe in refractory chronic migraine patients.PMID:37740562 | DOI:10.1111/head.14636 (Source: Headache)
Source: Headache - September 23, 2023 Category: Neurology Authors: Victor S Wang Justin Kosman Hsiangkuo Yuan Clinton Lauritsen Stephen Shrewsbury Sheena K Aurora Mary Hopkins Stephen Silberstein Source Type: research

Neuropathic changes in corneal nerve endings-A potential objective biomarker for migraine frequency and response to treatment
Headache. 2023 Sep 23. doi: 10.1111/head.14630. Online ahead of print.NO ABSTRACTPMID:37740579 | DOI:10.1111/head.14630 (Source: Headache)
Source: Headache - September 23, 2023 Category: Neurology Authors: Nur Amalina Md Isa Shyam S Tummanapalli Jeremy Chung Bo Chiang Arun V Krishnan Alessandro S Zagami Eric B Papas Maria Markoulli Katherine Spira Source Type: research

Safety, tolerability, and effectiveness of repetitive intravenous dihydroergotamine for refractory chronic migraine with cardiovascular risk factors: A retrospective study
CONCLUSION: Patients receiving intravenous DHE by the Jefferson Headache Center inpatient headache protocol had significantly reduced pain severity at discharge. No clinically significant cardiac or electrocardiogram abnormalities were detected in patients with elevated (or low) atherosclerotic cardiovascular disease risk. Repetitive intravenous DHE used by our protocol was safe in refractory chronic migraine patients.PMID:37740562 | DOI:10.1111/head.14636 (Source: Headache)
Source: Headache - September 23, 2023 Category: Neurology Authors: Victor S Wang Justin Kosman Hsiangkuo Yuan Clinton Lauritsen Stephen Shrewsbury Sheena K Aurora Mary Hopkins Stephen Silberstein Source Type: research

Neuropathic changes in corneal nerve endings-A potential objective biomarker for migraine frequency and response to treatment
Headache. 2023 Sep 23. doi: 10.1111/head.14630. Online ahead of print.NO ABSTRACTPMID:37740579 | DOI:10.1111/head.14630 (Source: Headache)
Source: Headache - September 23, 2023 Category: Neurology Authors: Nur Amalina Md Isa Shyam S Tummanapalli Jeremy Chung Bo Chiang Arun V Krishnan Alessandro S Zagami Eric B Papas Maria Markoulli Katherine Spira Source Type: research

Safety, tolerability, and effectiveness of repetitive intravenous dihydroergotamine for refractory chronic migraine with cardiovascular risk factors: A retrospective study
CONCLUSION: Patients receiving intravenous DHE by the Jefferson Headache Center inpatient headache protocol had significantly reduced pain severity at discharge. No clinically significant cardiac or electrocardiogram abnormalities were detected in patients with elevated (or low) atherosclerotic cardiovascular disease risk. Repetitive intravenous DHE used by our protocol was safe in refractory chronic migraine patients.PMID:37740562 | DOI:10.1111/head.14636 (Source: Headache)
Source: Headache - September 23, 2023 Category: Neurology Authors: Victor S Wang Justin Kosman Hsiangkuo Yuan Clinton Lauritsen Stephen Shrewsbury Sheena K Aurora Mary Hopkins Stephen Silberstein Source Type: research

Neuropathic changes in corneal nerve endings-A potential objective biomarker for migraine frequency and response to treatment
Headache. 2023 Sep 23. doi: 10.1111/head.14630. Online ahead of print.NO ABSTRACTPMID:37740579 | DOI:10.1111/head.14630 (Source: Headache)
Source: Headache - September 23, 2023 Category: Neurology Authors: Nur Amalina Md Isa Shyam S Tummanapalli Jeremy Chung Bo Chiang Arun V Krishnan Alessandro S Zagami Eric B Papas Maria Markoulli Katherine Spira Source Type: research