A review of 95 pit viper envenomations in Northcentral Florida (2018-2020)
This study's primary objectives were to record the clinical abnormalities and treatment responses associated with envenomation and their relation to outcome. Approximately 80% of the bites involved the head region associated with varying degrees of hemorrhagic lymphedema. Some of the most common additional symptoms observed were; hypotension (10%), cardiac dysrhythmias (17%), and coagulopathy (21%). Treatment in most cases consisted of intravenous fluids, antivenom, and analgesic drugs. Blood products were used as indicated for anemia and persistent bleeding. The average dose of the F('ab')2 was 1-2 vials. Additional vials...
Source: Toxicon - May 9, 2023 Category: Toxicology Authors: Taylor E Bassett Michael Schaer Source Type: research
Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: in-vitro optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation
CONCLUSION: Thus, CCA nanoparticles are considered as a candidate nanocarriers for fortifying the topical antihistaminic activity of DHH.PMID:37158038 | DOI:10.1080/03639045.2023.2211672 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - May 9, 2023 Category: Drugs & Pharmacology Authors: Sandy N Aziz Alia A Badawy Demiana I Nessem Nevine S Abd El Malak Marianne J Naguib Source Type: research
Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: < em > in-vitro < /em > optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation
CONCLUSION: Thus, CCA nanoparticles are considered candidate nanocarriers for fortifying the topical antihistaminic activity of DHH.PMID:37158038 | DOI:10.1080/03639045.2023.2211672 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - May 9, 2023 Category: Drugs & Pharmacology Authors: Sandy N Aziz Alia A Badawy Demiana I Nessem Nevine S Abd El Malak Marianne J Naguib Source Type: research
A review of 95 pit viper envenomations in Northcentral Florida (2018-2020)
This study's primary objectives were to record the clinical abnormalities and treatment responses associated with envenomation and their relation to outcome. Approximately 80% of the bites involved the head region associated with varying degrees of hemorrhagic lymphedema. Some of the most common additional symptoms observed were; hypotension (10%), cardiac dysrhythmias (17%), and coagulopathy (21%). Treatment in most cases consisted of intravenous fluids, antivenom, and analgesic drugs. Blood products were used as indicated for anemia and persistent bleeding. The average dose of the F('ab')2 was 1-2 vials. Additional vials...
Source: Toxicon - May 9, 2023 Category: Toxicology Authors: Taylor E Bassett Michael Schaer Source Type: research
Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: < em > in-vitro < /em > optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation
CONCLUSION: Thus, CCA nanoparticles are considered candidate nanocarriers for fortifying the topical antihistaminic activity of DHH.PMID:37158038 | DOI:10.1080/03639045.2023.2211672 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - May 9, 2023 Category: Drugs & Pharmacology Authors: Sandy N Aziz Alia A Badawy Demiana I Nessem Nevine S Abd El Malak Marianne J Naguib Source Type: research
Diphenhydramine/hydrocortisone/trastuzumab
(Source: Reactions Weekly)
Source: Reactions Weekly - May 1, 2023 Category: Drugs & Pharmacology Source Type: research
Suspected Suicide Attempts by Self-Poisoning Among Persons Aged 10-19 Years During the COVID-19 Pandemic - United States, 2020-2022
MMWR Morb Mortal Wkly Rep. 2023 Apr 21;72(16):426-430. doi: 10.15585/mmwr.mm7216a3.ABSTRACTThe World Health Organization declared COVID-19 a global pandemic on March 11, 2020 (1). As strategies to mitigate the pandemic were implemented, concerns were raised that the containment efforts through quarantine and social distancing practices were negatively affecting the mental and physical health of children and adolescents (2). Suicide is a growing public health problem in the United States. In 2020, suicide was the second leading cause of death among persons aged 10-14 years and the third leading cause among those aged 15-24 ...
Source: MMWR Morb Mortal Wkl... - April 21, 2023 Category: Epidemiology Authors: Rita Farah Saumitra V Rege Ryan J Cole Christopher P Holstege Source Type: research
Suspected Suicide Attempts by Self-Poisoning Among Persons Aged 10-19 Years During the COVID-19 Pandemic - United States, 2020-2022
MMWR Morb Mortal Wkly Rep. 2023 Apr 21;72(16):426-430. doi: 10.15585/mmwr.mm7216a3.ABSTRACTThe World Health Organization declared COVID-19 a global pandemic on March 11, 2020 (1). As strategies to mitigate the pandemic were implemented, concerns were raised that the containment efforts through quarantine and social distancing practices were negatively affecting the mental and physical health of children and adolescents (2). Suicide is a growing public health problem in the United States. In 2020, suicide was the second leading cause of death among persons aged 10-14 years and the third leading cause among those aged 15-24 ...
Source: MMWR Morb Mortal Wkl... - April 21, 2023 Category: Epidemiology Authors: Rita Farah Saumitra V Rege Ryan J Cole Christopher P Holstege Source Type: research
Suspected Suicide Attempts by Self-Poisoning Among Persons Aged 10-19 Years During the COVID-19 Pandemic - United States, 2020-2022
MMWR Morb Mortal Wkly Rep. 2023 Apr 21;72(16):426-430. doi: 10.15585/mmwr.mm7216a3.ABSTRACTThe World Health Organization declared COVID-19 a global pandemic on March 11, 2020 (1). As strategies to mitigate the pandemic were implemented, concerns were raised that the containment efforts through quarantine and social distancing practices were negatively affecting the mental and physical health of children and adolescents (2). Suicide is a growing public health problem in the United States. In 2020, suicide was the second leading cause of death among persons aged 10-14 years and the third leading cause among those aged 15-24 ...
Source: MMWR Morb Mortal Wkl... - April 21, 2023 Category: Epidemiology Authors: Rita Farah Saumitra V Rege Ryan J Cole Christopher P Holstege Source Type: research
Suspected Suicide Attempts by Self-Poisoning Among Persons Aged 10-19 Years During the COVID-19 Pandemic - United States, 2020-2022
MMWR Morb Mortal Wkly Rep. 2023 Apr 21;72(16):426-430. doi: 10.15585/mmwr.mm7216a3.ABSTRACTThe World Health Organization declared COVID-19 a global pandemic on March 11, 2020 (1). As strategies to mitigate the pandemic were implemented, concerns were raised that the containment efforts through quarantine and social distancing practices were negatively affecting the mental and physical health of children and adolescents (2). Suicide is a growing public health problem in the United States. In 2020, suicide was the second leading cause of death among persons aged 10-14 years and the third leading cause among those aged 15-24 ...
Source: MMWR Morb Mortal Wkl... - April 21, 2023 Category: Epidemiology Authors: Rita Farah Saumitra V Rege Ryan J Cole Christopher P Holstege Source Type: research
A Peculiar Case of Idiopathic Herpes-Zoster-Like Stevens-Johnson Syndrome (SJS)
We report a rare case of suspected herpes-zoster virus (HZV)-like SJS with negative HZV serum PCR and negative varicella-zoster virus (VZV) biopsy immunostaining. This rare case of SJS was resolved with the administration of IV acyclovir and Benadryl.PMID:37065287 | PMC:PMC10104479 | DOI:10.7759/cureus.36190 (Source: Herpes)
Source: Herpes - April 17, 2023 Category: Infectious Diseases Authors: Desiree E Ojo Farah Tiab David Walden Seth Bernacki Mariel Bagley Source Type: research
A Peculiar Case of Idiopathic Herpes-Zoster-Like Stevens-Johnson Syndrome (SJS)
We report a rare case of suspected herpes-zoster virus (HZV)-like SJS with negative HZV serum PCR and negative varicella-zoster virus (VZV) biopsy immunostaining. This rare case of SJS was resolved with the administration of IV acyclovir and Benadryl.PMID:37065287 | PMC:PMC10104479 | DOI:10.7759/cureus.36190 (Source: Herpes)
Source: Herpes - April 17, 2023 Category: Infectious Diseases Authors: Desiree E Ojo Farah Tiab David Walden Seth Bernacki Mariel Bagley Source Type: research
Comparison of the preventive effect of colchicine versus diphenhydramine, prednisolone, and a combination therapy on intraperitoneal adhesion bands: an experimental study in rats
Peritoneal adhesion formation is an inevitable consequence of abnormal repair of the peritoneum following different peritoneal injuries of intra-abdominal operations with the subsequent morbidity that they rep... (Source: BMC Surgery)
Source: BMC Surgery - April 10, 2023 Category: Surgery Authors: Seyed Ali Malekhosseini, Behzad Alizadeh, Ahmad Hosseinzadeh, Reza Shahriarirad, Reyhaneh Naseri, Kourosh Kazemi, Alireza Shamsaeefar and Nader Tanideh Tags: Research Source Type: research
Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease
CONCLUSION: Recombinant humanized anti-HER2 monoclonal antibody, administered as a single agent, produces durable objective responses and is well tolerated by women with HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. Side effects that are commonly observed with chemotherapy, such as alopecia, mucositis, and neutropenia, are rarely seen.PMID:36881998 | DOI:10.1200/JCO.22.02510 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - March 7, 2023 Category: Cancer & Oncology Authors: Melody A Cobleigh Charles L Vogel Debu Tripathy Nicholas J Robert Susy Scholl Louis Fehrenbacher Janet M Wolter Virginia Paton Steven Shak Gracie Lieberman Dennis J Slamon Source Type: research
