Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Pertussis epidemiology in Canada, 2005-2019
CONCLUSION: The highest morbidity and fatality of pertussis were among infants under one year of age. It is important to take measures to reduce transmission to infants who are too young to be vaccinated. Increasing vaccine coverage in children and pregnant women are important to reduce the burden of disease.PMID:36815868 | PMC:PMC9902035 | DOI:10.14745/ccdr.v49i01a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 23, 2023 Category: Infectious Diseases Authors: Disha Bhagat Myriam Saboui Grace Huang Francesca Reyes Domingo Susan G Squires Marina I Salvadori Y Anita Li Source Type: research

Fast and visual detection of nucleic acids using a one-step RPA-CRISPR detection (ORCD) system unrestricted by the PAM
Anal Chim Acta. 2023 Apr 1;1248:340938. doi: 10.1016/j.aca.2023.340938. Epub 2023 Feb 3.ABSTRACTCRISPR-Cas12a (Cpf1) is widely used for pathogen detection. However, most Cas12a nucleic acid detection methods are limited by a PAM sequence requirement. Moreover, preamplification and Cas12a cleavage are separate. Here, we developed a one-step RPA-CRISPR detection (ORCD) system unrestricted by the PAM sequence with high sensitivity and specificity that offers one-tube, rapid, and visually observable detection of nucleic acids. In this system, Cas12a detection and RPA amplification are performed simultaneously, without separate...
Source: Analytica Chimica Acta - February 22, 2023 Category: Chemistry Authors: Kangfeng Lin Jianguang Guo Xiangju Guo Qinghan Li Xiao Li Zhen Sun Zehang Zhao Jiao Weng Jinzhun Wu Rui Zhang Boan Li Source Type: research