Why I Seldom Recommend Vitamins or Supplements
By HANS DUVEFELT People here in northern Maine, as in my native Sweden, don’t get a whole lot of natural sunlight a good part of the year. As a kid, I had to swallow a daily spoonful of cod liver oil to get the extra vitamin D my mother and many others believed we all needed. Some years later, that fell out of fashion as it turned out that too much vitamin A, also found in that particular dubious marine delicacy, could be harmful. This is how it goes in medicine: Things that sound like a good idea often turn out to be not so good, or even downright bad for you. Other vitamins, like B12, can also cause harm: Exce...
Source: The Health Care Blog - July 2, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Hans Duvefelt primary care supplements vitamins Source Type: blogs

Fight Aging! Newsletter, May 24th 2021
In conclusion, we showed that addition of resistance exercise training, but not dietary EAAs, to the myostatin inhibition further increased muscle mass through the attenuation of muscle protein breakdown with proportionate improvements in muscle strength. Interestingly, addition of dietary EAAs to the myostatin inhibition with or without resistance exercise training improved muscle quality. Thus, dissection of the underlying mechanisms behind the combined positive effect of dietary EAAs and resistance exercise training on muscle mass and quality can shed light on the discovery of effective therapeutics against muscle wasti...
Source: Fight Aging! - May 23, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

On Balance, Vegetarians Exhibit Better Biomarkers than Non-Vegetarians
There is a fair amount of epidemiological data to suggest that vegetarians have, on balance, better long-term health prospects than people who consume meat. The usual caveats apply, in that vegetarianism in many wealthier study populations is correlated with a range of other potentially relevant line items, such as education, wealth, and better lifestyle choices. Further, the average vegetarian may well be mildly calorie restricted in comparison to the average meat eater, and that may be enough in and of itself to explain health effects. Other suggested contributing factors include dietary advanced glycation end-products, ...
Source: Fight Aging! - May 18, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, May 10th 2021
This study suggests that some of those changes contribute to age-related hypertension, providing yet another reason to put resources into the near term development of therapies that can reverse the aging of the gut microbiome, such as flagellin vaccination or fecal microbiota transplantation. "Previous studies from our lab have shown that the composition of the gut microbiota in animal models of hypertension, such as the SHRSP (spontaneously hypertensive stroke-prone) rat model, is different from that in animals with normal blood pressure. Further, transplanting dysbiotic gut microbiota from a hypertensive animal ...
Source: Fight Aging! - May 9, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

An Assessment of Various Lifestyle Interventions to Treat Sarcopenia
In this study, we performed secondary analyses of data in a randomized controlled trial of multi-domain lifestyle interventions (6-month duration physical exercise, nutritional enrichment, cognitive training, combination and standard care control) among 246 community-dwelling pre-frail and frail elderly, aged ≥65 years, with and without sarcopenia. We observed that multi-domain physical, nutritional, and cognitive interventions among pre-frail and frail older adults were associated with favorable changes in sarcopenia and blood biomarkers underlying the muscle mass and physical functional response to intervention...
Source: Fight Aging! - May 7, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

3 Tips To Help You Avoid Feeling Burnt Out
Had you known adult life would've been so stressful, perhaps you would've remained a child. Regardless, confronting life's difficulties is part of all our lives. Letting those confrontations burn you out is easier than it sounds. When you've been starting to waiver, you might wonder what's going wrong? Burnout can be caused by many things. Fortunately, we've all been in your shoes, and we've learned several ways to overcome those difficulties. 1. Learning How to Better Manage Your Time First and foremost, time seems to be the common denominator among most cases of burnout. Learning how to manage time more effectively...
Source: PickTheBrain | Motivation and Self Improvement - April 27, 2021 Category: Consumer Health News Authors: Erin Falconer Tags: creativity depression featured happiness health and fitness psychology self-improvement success burnout pickthebrain stress time management Source Type: blogs

VITAL trial on vitamin D
Role of vitamin D in cardiovascular disease has been suggested by observational studies. Low blood levels of vitamin D was found to be associated with higher risks of heart disease, stroke, hypertension and diabetes mellitus [1]. But the 2011 Institute of Medicine (United States) guidance concluded that the evidence is inconsistent and inconclusive, not meeting the criteria for a cause effect relationship [2]. VITAL study was a randomized placebo controlled trial of vitamin D3 (cholecalciferol) at a dose of 2000 IU per day and omega-3 fatty acids at a dose of 1 g per day for prevention of cancer and cardiovascular diseas...
Source: Cardiophile MD - April 18, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Do vitamin D, zinc, and other supplements help prevent COVID-19 or hasten healing?
In this study, people whose symptoms did not require hospital admission were randomly assigned to receive only vitamin C, 8,000 mg/day (the recommended daily amount is 75 mg/day for women and 90 mg/day for men) only zinc, 50 mg/day (the recommended daily amount is 8 mg/day for women, 11 mg/day for men) both supplements at the doses above neither supplement. The researchers found that people receiving the supplements, whether individually or combined, had no improvement in symptoms or a faster recovery when compared with otherwise similar patients receiving neither supplement. Proponents of melatonin for COVID-19 have enc...
Source: Harvard Health Blog - April 5, 2021 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Vitamins and supplements Source Type: blogs

4 essential nutrients — are you getting enough?
The newest dietary guidelines for Americans say that many Americans don’t get enough of four vital nutrients. Over time, a shortfall of these nutrients may affect different aspects of your health, from teeth and bones to your heart, gut, muscles, blood pressure, weight, and more. What is a nutritional shortfall? Nutritional advice can be confusing. Eat more of this, less of that. Make sure you get enough — but not too much. It’s no wonder many people have so-called nutritional shortfalls, where their diet lacks sufficient essential nutrients. So, which nutrients do you really need and how much? And what key nutri...
Source: Harvard Health Blog - March 16, 2021 Category: Consumer Health News Authors: Matthew Solan Tags: Health Healthy Eating Nutrition Source Type: blogs

Fight Aging! Newsletter, March 15th 2021
In conclusion, PLG attenuates high calcium/phosphate-induced vascular calcification by upregulating P53/PTEN signaling in VSMCs. Tsimane and Moseten Hunter-Gatherers Exhibit Minimal Levels of Atrial Fibrillation https://www.fightaging.org/archives/2021/03/tsimane-and-moseten-hunter-gatherers-exhibit-minimal-levels-of-atrial-fibrillation/ Epidemiological data for the Tsimane and Moseten populations in Bolivia shows that they suffer very little cardiovascular disease in later life, despite a presumably greater lifetime burden of infectious disease (and consequent inflammation) than is the case for people ...
Source: Fight Aging! - March 14, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Piperlongumine Reduces Aortic Calcification in Mice
In conclusion, PLG attenuates high calcium/phosphate-induced vascular calcification by upregulating P53/PTEN signaling in VSMCs. (Source: Fight Aging!)
Source: Fight Aging! - March 12, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Could what we eat improve our sleep?
We think of eating a nutritious diet and exercising as healthy behaviors, but sleep is one of the pillars of a healthy lifestyle. Why is this? Sleep sets the stage for our days. If we experience sound sleep for seven to eight hours, we arise energized in the morning. Diet, exercise, and sleep work synergistically, and affect one another. All three can have an effect on our daily well-being and longevity. To be well and vital and help prevent certain diseases, like obesity, heart disease, high blood pressure, stroke, diabetes, and many other conditions, we need to prioritize sleep. When we make sleep a priority, we can impr...
Source: Harvard Health Blog - March 9, 2021 Category: Consumer Health News Authors: Elizabeth Pegg Frates, MD Tags: Diet and Weight Loss Healthy Eating Mental Health Prevention Sleep Source Type: blogs

Correlative Adventures with COVID
By ANISH KOKA “The patient in room 1 should be a quick one, its an addon, they just need a prescription for ivermectin” I’m a bit puzzled by this sentence from my assistant doing his best to help me through a very busy day in the clinic that I’m already behind in. I walk into the room, a script pad stuffed into my hand as I enter the room, to meet a very nice couple.  The wife sits patiently with hands crossed on the exam table.  “So, you’re here for Ivermectin?”, I ask. Why yes, a trip to Texas is planned.. COVID is in the air, the internet, and some important people who have ‘inside ...
Source: The Health Care Blog - March 5, 2021 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Anish Koka COVID vaccine COVID-19 vaccine Ivermectin Source Type: blogs

Is there a role for vitamin D in COVID-19? [PODCAST]
“As we continue to deal with the COVID-19 pandemic causing spiking numbers of cases, the scientific and medical communities continue to search for effective treatments and preventive measures. We have clearly established the importance of wearing masks, physical distancing, and frequent handwashing. As of this article ’s writing, there are over two hundred fifty articles on […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 28, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Nutrition Source Type: blogs

What's new in midwifery - 3rd February 2021
Some recent things you might need to know.First, aCochrane review looking at single dose nonsteroidal anti-inflammatory drugs for perineal pain in the postpartum period.And then an analysis inJAMA Network Open of a randomised trial of high dose vitamin D in pregnancy  and its effects on neurodevelopment in children.  The trial compared high dose vitamin D with the standard dose.Last of all, a Guardian article discussing reports thatpregnant women having to attend scans alone are not being allowed to film the scan.Stay safe. (Source: Browsing)
Source: Browsing - February 3, 2021 Category: Databases & Libraries Tags: midwifery Source Type: blogs