Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial
We describe the planned descriptive analyses, the main analysis of the primary end point, our approach to secondary and exploratory analyses, and handling of missing data. Our goal is to provide enough detail that our approach could be replicated by an independent study group, thereby enhancing the transparency of the study.Trial registrationClinicalTrials.gov,NCT03509350. Registered on 26 April 2018. (Source: Trials)
Source: Trials - December 3, 2019 Category: Research Source Type: clinical trials
Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis
Condition: Sepsis Interventions: Drug: Hydrocortisone, Ascorbic acid, Thiamine; Drug: Normal saline Sponsors: Tanta University; Mostafa Ismail Sharaf; Salah Eldeen Ibrahim Alsherif; Mohamed Mohi El deen Abo El yazeed Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2019 Category: Research Source Type: clinical trials
Steroids, Thiamine and Ascorbic Acid in Septic Shock
Condition: Septic Shock Intervention: Drug: STASIS Sponsors: Baqiyatallah Medical Sciences University; Hamadan University of Medical Science; Tehran University of Medical Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 22, 2019 Category: Research Source Type: clinical trials
