Fire acupuncture for mild to moderate knee osteoarthritis: a protocol for a randomized controlled pilot trial
This study is a prospective randomized controlled pilot trial in which 120 patients with mild to moderate KOA will be randomly allocated in equal proportions to a fire acupuncture group or a general acupuncture group. They will receive acupuncture for six sessions over 2 weeks. The primary end point is success rate, which will be calculated based on the change from baseline of the pain and function scores in the Western Ontario and McMaster Universities Osteoarthritis Index at 4 weeks. Secondary end points include the proportion of patients achieving clinical i mprovement based on: (1) the OMERACT-OARSI responder crit...
Source: Trials - December 3, 2019 Category: Research Source Type: clinical trials
Labelled Carbon Sucrose Breath Test (13C-SBT) as a Marker of Environmental Enteropathy
Conditions: Glucose-Galactose Malabsorption; Enteropathy; Malnutrition, Child; Intestinal Permeability; Linear Growth Failure Intervention: Sponsors: University of Virginia; International Atomic Energy Agency; Flinders University; International Centre for Diarrhoeal Disease Research, Bangladesh; St. John's Research Institute; The University of The West Indies; Mmust Masinde Muliro University of Science and Tech nology; Asociación Benéfica Prisma; Scottish Universities Environmental Research Centre; University of Michigan; Tropical Diseases Resear...
Source: ClinicalTrials.gov - September 30, 2019 Category: Research Source Type: clinical trials
Acupuncture of different treatment frequency in knee osteoarthritis: a protocol for a pilot randomized clinical trial
This study aims to determine whether 3 sessions per week of acupuncture treatment is superior to 1 session per week of acupuncture treatment for symptomatic outcomes in knee osteoarthritis.Methods/designThis is a two parallel-group, assessor-blinded, randomized controlled trial. Sixty patients with knee osteoarthritis (Kellgren –Lawrence grade II or III) will be recruited and randomly allocated to receive 24 or 8 sessions (group M or group L) of acupuncture treatment in a 1:1 ratio. Patients in group M will receive 3 sessions per week of acupuncture for 8 weeks. Patients in group L will receive acupuncture once per wee...
Source: Trials - July 10, 2019 Category: Research Source Type: clinical trials
Study on efficacy and safety of Tong-luo Qu-tong plaster treatment for knee osteoarthritis: study protocol for a randomized, double-blind, parallel positive controlled, multi-center clinical trial
This study will be a randomized, double-blind, parallel positive controlled, multi-center clinical trial, a non-inferiority trial design was adopted. A total of 2000 participants older than 40 years, with KOA, will be randomly allocated into an experimental group (n = 1500) and a control group (n = 500). All participants will receive a conventional conservative treatment lasting for 14 days as two courses, once daily. Tong-luo Qu-tong plaster will be administered externally to participants in the experimental group, while the control group will receive a Qi-zheng Xiao-tong plaster. Th e outcome of the total We...
Source: Trials - June 23, 2019 Category: Research Source Type: clinical trials
Evaluation of repositories for sharing individual-participant data from clinical studies
ConclusionsOur evaluation, though often hampered by the lack of sufficient information, can help researchers to find a suitable repository for their datasets. Some repositories are more mature because of their support for clinical dataset preparation, contractual agreements, metadata and identifiers, different modalities of access, and long-term preservation of data. Further work is now required to achieve a more robust and accurate system for evaluation, which in turn may encourage the sharing of clinical study data.Trial registrationStudy protocol available athttps://zenodo.org/record/1438261#.W64kW9Egrcs. (Source: Trials)
Source: Trials - March 14, 2019 Category: Research Source Type: clinical trials
