The “open data” movement runs aground on FOURIER
BY ANISH KOKA
Reanalysis of a trial used to approve a commonly used injectable cholesterol-lowering drug confirms the original analysis by accident.
The open-data movement seeks to liberate the massive amount of data generated in running clinical trials from the grasp of the academic medical-pharmaceutical industrial complex that mostly runs the most important trials responsible for bringing novel therapeutics to market.
There are only a few elite academic trialist groups capable of running large trials and there’s ample reason to be suspicious about the nexus that has developed between academia and the pharmace...
Source: The Health Care Blog - January 19, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Uncategorized Source Type: blogs
The Open Data Movement Runs Aground on FOURIER
BY ANISH KOKA
Reanalysis of a trial used to approve a commonly used injectable cholesterol-lowering drug confirms the original analysis by accident.
The open-data movement seeks to liberate the massive amount of data generated in running clinical trials from the grasp of the academic medical-pharmaceutical industrial complex that mostly runs the most important trials responsible for bringing novel therapeutics to market.
There are only a few elite academic trialist groups capable of running large trials and there’s ample reason to be suspicious about the nexus that has developed between academia and the pharmace...
Source: The Health Care Blog - January 19, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Anish Koka FDA regulations Fourier open data Source Type: blogs
More on the Work of the Longevity Escape Velocity Foundation
The Longevity Escape Velocity Foundation (LEVF) is initially working to assess combinations of approaches to the treatment of aging, to assess the degree to which mouse life span is affected. Aging consists of many distinct mechanisms, and comprehensive rejuvenation will require a diverse package of therapies. Yet the research and development community undertakes little work on combined treatments. Here, the Lifespan.io team talks to Aubrey de Grey about some of the details of the work presently under way.
We are obviously very excited about LEVF's robust mouse rejuvenation (RMR) project. Could you walk our reader...
Source: Fight Aging! - January 18, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Congressional Pay for Performance: No Budget, No Pay
Romina BocciaImagine you are an executive at a major corporation. One of the core responsibilities of your job is to collaborate with the other executives to adopt budget and organizational policies for your corporation each year. Instead of meeting your responsibilities, most years the corporation is forced to operate without a budget as outdated policies continue and the firm bleeds red ink. Such a dysfunctional corporation likely wouldn ’t last very long. You and the other executives would also likely face pay cuts, before eventually getting fired.Now, imagine this same scenario, but you ’re a me...
Source: Cato-at-liberty - January 17, 2023 Category: American Health Authors: Romina Boccia Source Type: blogs
Flight Chaos Demonstrates Need for Systemic Changes in Air Traffic Control Policy
Colin GrabowAir travel in the United States was thrown into chaos earlier this week when a key system used by the Federal Aviation Administration (FAA) went down, forcing over10,000 flights to be delayed and at least 1,300 canceled. While a damageddatabase file may have been the proximate cause of this upheaval, the episode appears yet another indication of systemic flaws in U.S. air traffic control policy.Technological deficiencies in U.S. air traffic control operations arelong-standing. Indeed, Congress mandatedtwenty years ago that the FAA establish a plan for implementing the modernized Next Generation A...
Source: Cato-at-liberty - January 13, 2023 Category: American Health Authors: Colin Grabow Source Type: blogs
The IRS Spares the Side ‐Hustlers (For Now)
Scott Lincicome and Ilana BlumsackAs our colleague Nick Anthonywrites, the IRS in late ‐Decemberpostponed a new rule requiring Americans to report to the IRS gross annual online sales (including taxes, fees, canceled orders, or even the nontaxable resale of goods at a loss) of as little as $600 – considerably lower than the current reporting threshold of $20,000 in payments and 200 transactions. As Nick notes, the new requirement (reported primarily on IRS Forms 1099‑K and now punted to next year) constitutes a major invasion of Americans’ financial privacy.As weexplain in a chapter of the new Cato book,E...
Source: Cato-at-liberty - January 7, 2023 Category: American Health Authors: Scott Lincicome, Ilana Blumsack Source Type: blogs
Baseball, Taxes, and Apple Pie
David BoazKen Rosenthal of The Athleticwrites:TheAngels were in the mix for free ‐agent right‐handerNathan Eovaldi, but faced two disadvantages. One was Eovaldi ’s desire to return to his native Texas; he is from Alvin, about a five ‐hour drive from theRangers ’ home in Arlington. The other was the difference in state income taxes. California ’s top rate is 13.3 percent. Texas has no state income tax.So let ’s see. If Eovaldi is making $17 million a year, as reported, then that California tax would cost him about $2,226,000. Look at it another way: First, the feds take 37 percent of income ...
Source: Cato-at-liberty - January 6, 2023 Category: American Health Authors: David Boaz Source Type: blogs
IRS $600 Monitoring Paused
Nicholas AnthonyPayments amounting to $600 will soon need to be reported to the government, but the Internal Revenue Service (IRS)announced that it will be postponing the implementation of the reporting requirement for one year. Although the requirement is not quite as invasive as when Congress was considering enacting surveillance on bank accounts with $600 in yearly activity, it ’s not far off.Acting IRS CommissionerDoug O ’Donnell said, “The IRS and Treasury heard a number of concerns regarding the timeline of implementation of these changes under the American Rescue Plan. … The additional time will he...
Source: Cato-at-liberty - January 6, 2023 Category: American Health Authors: Nicholas Anthony Source Type: blogs
Trading One Dream Job for Another
Anastasia P. BodenThis week I left my job suing the government to join the Cato Institute as Director of the Center for Constitutional Studies. The reactions have been overwhelmingly positive and I ’m thrilled to return to an organization I’ve long respected. Many are now asking why I chose to leave what I still describe as a dream job.Some of my responses are conventional: I had been a civil rights attorney for ten years. Change is good. Litigation is all ‐consuming. And at some point, people seek new challenges. But I also came to believe I could be a more effective a...
Source: Cato-at-liberty - January 5, 2023 Category: American Health Authors: Anastasia P. Boden Source Type: blogs
Healthcare Workforce – 2023 Health IT Predictions
As we head into 2023, we wanted to kick off the new year with a series of 2023 Health IT predictions. We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes. Check out our communities predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media.
Check out our community’s healthcare workforce predictions.
Kelly Conklin, Chief Clinical Officer at PerfectServe
Let’s be real—nurses are, to put it lightly, still being stretched v...
Source: EMR and HIPAA - January 5, 2023 Category: Information Technology Authors: John Lynn Tags: C-Suite Leadership Health IT Company Healthcare IT 2023 Health IT Predictions athenahealth Bright.md Caregility Cedar Chris Baird Chris Sullivan Emily Goetz Florian Otto Grace Nam Healthcare Staffing Healthcare Workforce Iman Source Type: blogs
Infrastructure Act ’s Cryptocurrency Reporting on Hold, Says IRS
Nicholas AnthonyIn the final days of 2022, theInternal Revenue Service (IRS) announced that the Infrastructure Investment and Jobs Act ’s infamous cryptocurrency reporting requirements were being put on hold. While this sudden change is far more welcome than when Congresswrote the law seemingly overnight in late 2021, the temporary pause shouldn ’t distract from the fact that the reporting requirements should be repealed entirely.A Quick Refresher on the Infrastructure ActAs the name suggests, theInfrastructure Investment and Jobs Act was primarily written with the supposed intention of rebuildingroads, bridges, railwa...
Source: Cato-at-liberty - January 4, 2023 Category: American Health Authors: Nicholas Anthony Source Type: blogs
Empowering Remote Work
Scott Lincicome and Ilana BlumsackEver since the Covid ‐19 pandemic upended our lives, remote work has blossomed. Online job search company Ladders, for example, recentlyfound that remote work opportunities in the summer of 2022 accounted for 36 percent of job openings on the site. And while remote work has declined since its Spring 2020 peak, the arrangement remains far more common today than it was before the pandemic (see Figure 1). New research from Stanford ’s Nick Bloomshows that this substantial, three ‐year rise is the equivalent of50 years of pre ‐pandemic remote work growth.Remote work not only...
Source: Cato-at-liberty - December 21, 2022 Category: American Health Authors: Scott Lincicome, Ilana Blumsack Source Type: blogs
Five Things to Know About the Monstrous Lame Duck Omnibus
Romina BocciaJust asI predicted back in October, Congress pushed its discretionary spending deadline back by one week, from December 16 to December 23. This comes as no surprise as congressional leadership is once again trying to ram through a massive omnibus bill before the year ends. The Friday deadline gives leadership leverage, as they threaten a partial government shutdown that might keep members of Congress in Washington over Christmas. Vote as you ’re told, or you’re not going home is the name of this game.Yet in the same vein that Congress managed to punt on appropriations when they were due on S...
Source: Cato-at-liberty - December 21, 2022 Category: American Health Authors: Romina Boccia Source Type: blogs
Netflix for Drugs?
By KIM BELLARD
A relative — obviously overestimating my healthcare expertise — asked my thoughts on The New York Times article Can a Federally Funded ‘Netflix Model’ Fix the Broken Market for Antibiotics? I had previously skimmed the article and was vaguely aware of the Pasteur Act that it discusses, but, honestly, my immediate reaction to the article was, gosh, that may not be a great analogy: do people realize what a tough year Netflix has had?
I have to admit that I tend to stay away from writing about Big Pharma and prescription drugs, mainly because, in a US healthcare system that seems to pride i...
Source: The Health Care Blog - December 21, 2022 Category: Consumer Health News Authors: matthew holt Tags: The Business of Health Care Congress Kim Bellard Netflix Pharma Pharmaceutical industry Source Type: blogs
