Antibiotic-resistant superbugs killed 1.2MILLION people in 2019 - more than HIV or malaria
Superbugs, bacteria resistant to commonly prescribed antibiotics caused 1.2million deaths could have been a factor in nearly 5million a study by experts Washington and Oxford has found. (Source: the Mail online | Health)
Source: the Mail online | Health - January 19, 2022 Category: Consumer Health News Source Type: news
Nasal screening for methicillin-resistant Staphylococcus aureus does not reduce surgical site infection after primary lumbar fusion
Background Context: Preoperative methicillin-resistant Staphylococcus aureus (MRSA) testing and decolonization has demonstrated success for arthroplasty patients in surgical site infections (SSIs) prevention. Spine surgery, however, has seen varied results.
Purpose: The purpose of this study was to determine the impact of nasal MRSA testing and operative debridement rates on surgical site infection after primary lumbar fusion.
Study Design/setting: Retrospective cohort study and/or Consolidated medical enterprise PATIENT SAMPLE: Adult patients undergoing primary instrumented lumbar fusions from January 2015 to December 2...
Source: Current Awareness Service for Health (CASH) - January 17, 2022 Category: Consumer Health News Source Type: news
Efficacy of antimicrobial peptide LL-37 against biofilm forming Staphylococcus aureus strains obtained from chronic wound infections
The antimicrobial peptide LL-37 showed inhibitory effects against Staphylococcus aureus strains, which often responsible for wound infections. Understanding the molecular mechanisms of biofilm-containing wound infections is important. Thus, this study aimed to investigate both the antimicrobial and biofilm efficacy of LL-37 against biofilm-positive methicillin-susceptible S. aureus (MSSA) strains and biofilm-positive methicillin-resistant S. aureus (MRSA) strains obtained from chronic wound infections and its effect on different quorum sensing and virulence genes at suboptimal concentrations. Fifteen biofilm-forming MRSA a...
Source: Current Awareness Service for Health (CASH) - January 17, 2022 Category: Consumer Health News Source Type: news
Combined sterilization and fabrication of drug-loaded scaffolds using supercritical CO 2 technology
The access of biodegradable scaffolds to the clinical arena is constrained by the absence of a suitable sterilization technique for the processing of advanced polymeric materials. Sterilization with supercritical CO 2 (scCO 2 ) may circumvent some technological limitations (e.g., low temperature, no chemical residues on the material), although scCO 2 can plasticize the polymer depending on the processing conditions used. In this latter case, the integration of the manufacturing and sterilization processes is of particular interest to obtain sterile and customized scaffolds in a single step. In this work, scCO 2 was exploit...
Source: Current Awareness Service for Health (CASH) - January 17, 2022 Category: Consumer Health News Source Type: news
Antimicrobial effectiveness of wound matrices containing native extracellular matrix with polyhexamethylene biguanide
This study compares the antimicrobial and wound healing capabilities, both in vivo and in vitro against methicillin-resistant Staphylococcus aureus (MRSA) USA 300, for the following compounds: Collagen Wound Matrix-Anti Microbial (CWM-AM); Collagen Wound Matrix-Anti Microbial XT (CWM-AM XT); Antimicrobial Hydrofiber Wound Dressing (AHWD); Dermal Scaffold with Silver (DRSAg); Collagen Extracellular Matrix (CEM); Collagen Wound Matrix (CWM); Matrix Wound Dressing with Silver (MWDAg); Cadexomer Iodine Gel (CIG); Triple Antibiotic Ointment (TAO); and Antimicrobial Wound Gel (AWG). For the in vitro zone of inhibition assay, AWG...
Source: Current Awareness Service for Health (CASH) - January 17, 2022 Category: Consumer Health News Source Type: news
Effectiveness and real-world materials compatibility of a novel hydrogen peroxide disinfectant cleaner.
A novel 4% hydrogen peroxide disinfectant was effective against methicillin-resistant Staphylococcus aureus (MRSA), Clostridioides difficile spores, carbapenem-resistant Escherichia coli, and 2 strains of Candida auris. In laboratory testing, a sodium hypochlorite disinfectant caused fading and loss of pliability of a hospital mattress, but the hydrogen peroxide disinfectant did not. These findings suggest that the hydrogen peroxide-based disinfectant may be a useful addition to the sporicidal disinfectant products available for use in healthcare settings. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 14, 2021 Category: Consumer Health News Source Type: news
The use of functionalized nanoparticles to treat Staphylococcus aureus-based surgical-site infections: a systematic review.
Staphylococcus aureus-based surgical site infections have become the leading cause of failure for total joint arthroplasty operations and remain a major issue across surgical specialties. Moreover, S. aureus-based infections are becoming drastically more difficult to treat due to the development of antibiotic resistant strains and due to the bacteria ' s propensity to produce biofilms. The emergence of highly resistant S. aureus infections has created the need for a novel antimicrobial treatment. Functionalized nanoparticles have recently been suggested as being a viable option to fill this void due to their strong antimic...
Source: Current Awareness Service for Health (CASH) - December 14, 2021 Category: Consumer Health News Source Type: news
The half-hour superbug test 'that will save thousands of lives'
The test has been developed by scientists at Imperial College London, pictured, and can spot if an infection is resistant to powerful antibiotics almost immediately. (Source: the Mail online | Health)
Source: the Mail online | Health - December 11, 2021 Category: Consumer Health News Source Type: news
Africa: Protecting Antibiotic Effectiveness is an Urgent Public Health Priority
[allAfrica] Nairobi -- Every year, more than 700,000 people die from antibiotic-resistant infections - number expected to grow to 10 million annually by 2050 if we continue on the current path. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 1, 2021 Category: African Health Source Type: news
Protecting Environmental Water from Antimicrobial Resistance
By Lina Taing and Rachel KaiserHAMILTON, Canada, Nov 23 2021 (IPS) The overuse and misuse of antimicrobial medicines and chemicals has become the main driver of antimicrobial resistance (AMR) and drug-resistant infections that threaten human health and the global economy.
Given that development, the UN designated November 18-24 as World Antimicrobial Awareness Week, to remind us all to handle antimicrobials with greater care.
Antimicrobials – which range from antibiotic and antiviral medicines to disinfectant and antiseptic chemicals – help prevent or treat human, animal and plant infections and have contributed imme...
Source: IPS Inter Press Service - Health - November 23, 2021 Category: International Medicine & Public Health Authors: Lina Taing and Rachel Kaiser Tags: Climate Change Environment Global Headlines Health Population Poverty & SDGs TerraViva United Nations Water & Sanitation Source Type: news
Africa: Stronger Governance Needed to Fight Superbugs in Africa
[WHO-AFRO] Accra -- The leaders of six regional organizations in Africa are calling for stronger governance to fight antimicrobial resistance, or AMR, on the eve of World Antimicrobial Awareness Week (18-24 November). (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 18, 2021 Category: African Health Source Type: news
Poorer nations still lack access to world ’s key antibiotics
Only 54 of 166 assessed treatments have policies aiding use by low-income countries, says non-profit groupThe world ’s biggest drugs makers have pressed on in the fight against superbugs despite the pandemic, but millions of people in poorer countries, where the risk of drug-resistant infections is highest, are still missing out on key antibiotics.A report from the Access to Medicine Foundation, an Amsterdam-based non-profit group, shows that only 54 of 166 medicines and vaccines assessed are covered by an access strategy to make them available to low- and middle-income countries.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - November 18, 2021 Category: Science Authors: Julia Kollewe Tags: Pharmaceuticals industry Vaccines and immunisation Tuberculosis E coli Gonorrhoea World Health Organization Business Drug resistance Drugs Drugs policy Medical research Global development Science Netherlands World news Source Type: news
Antibiotic-resistant infections could trigger a new 'hidden pandemic', experts warn
Dr Susan Hopkins, head of the UK Health Security Agency, claimed it was important the country does not lurch from one crisis 'into another'. She urged Britons not to use the medicines for colds. (Source: the Mail online | Health)
Source: the Mail online | Health - November 17, 2021 Category: Consumer Health News Source Type: news
Antibiotic-resistant infections fell in 2020 for first time since 2016, but UKHSA warns drop likely temporary
New UKHSA data shows that bloodstream infections dropped in 2020 for the first time since 2016 but remain at a higher level than 6 years ago. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 17, 2021 Category: Consumer Health News Source Type: news
Hidden pandemic of antibiotic-resistant infections, health officials warn
Antibiotics should be taken only when really needed - and not for coughs, colds or sore throats. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - November 17, 2021 Category: Consumer Health News Source Type: news
