Elevated prosthetic valve gradients
Elevated gradients across prosthetic valves can occur due to various reasons. But before declaring that prosthetic valve gradients are elevated, the usual gradient across the given type of prosthetic valve should be known. Different types of normally functioning prosthetic heart valves have different gradients. Normal gradient is different between the various valve positions. Transmitral prosthetic valve gradient is lower than transaortic prosthetic valve gradient. If the gradient during post operative review is available, it can be used as a benchmark for comparison. Some of the important causes for elevated prosthetic ...
Source: Cardiophile MD - February 27, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiac Surgery Echocardiography Source Type: blogs

Does lupus or arthritis affect your prognosis if you get COVID-19?
Soon after the coronavirus pandemic began, we learned that older adults and people with certain chronic conditions, such as high blood pressure or diabetes, are at increased risk for severe COVID-19. One condition on that list is an immunocompromised state (a weakened immune system). This can be due to a number of conditions, including having had an organ transplant, having HIV, or taking medications that suppress the immune system. If you have an autoimmune condition such as rheumatoid arthritis or lupus (also called systemic lupus erythematosus), you may wonder how this affects your risk. It’s thought that these condit...
Source: Harvard Health Blog - November 9, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Autoimmune diseases Bones and joints Coronavirus and COVID-19 Source Type: blogs

“ Use of curcumin in multiple myeloma patients intolerant of steroid therapy ”
Conclusion”). The other 12 patients, however, are stable and doing well, in spite of the fact that some have high-risk cytogenetic and FISH abnormalities. The combination of curcumin and the other conventional drugs reduced their paraprotein levels by 38%, and plasmacytosis by 59%. How about that? Anyway, it’s not a difficult read, methinks, so please have a look at the above link… Thank you, Dr. Golombick! I am so grateful to you and your team for all your tireless work. You give us hope!!! :-) Thank You Thank You Thank You!!! We need MORE studies like this one! Not 10 years from now…but…NOW!...
Source: Margaret's Corner - February 28, 2020 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll curcumin Golombick myeloma Source Type: blogs

Pericardial effusion associated with Infective Endocarditis : Incidence , mechansim and clinical Implication.
Pericardial effusion is often detected in patients with Infective endocarditis. Incidence can be as high as 25% . Most often it is mild, can be moderate in few. Mechanism Sympathetic effusion in response to endocardial infection. It’s never more than minimal. (Evidence ? it’s only an assumption) IE related cardiac failure (Raised systemic venous pressure to which pericardial veins drain) Local sepsis, Abcess formation tracks to pericardial space through transmural lymphatics Fungal , granulomatous , Tuberculous IE (Rare) Here IE and PE  share the same pathology Part of systemic sepsis activated Immune mechan...
Source: Dr.S.Venkatesan MD - January 28, 2020 Category: Cardiology Authors: dr s venkatesan Tags: cardiology -Therapeutics Cardiology -unresolved questions Infrequently asked questions in cardiology (iFAQs) pericardial disease pericardial effusion Pericardium infective endocarditis pericardial effusion in infective endocarditis Source Type: blogs

Pricardial effusion associated with Infective Endocarditis : Incidence , mechansim and clinical Implication.
Pericardial effusion is often detected in patients with Infective endocarditis. Incidence can be as high as 25% . Most often it is mild, can be moderate in few. Mechanism Sympathetic effusion in response to endocardial infection. It’s never more than minimal. (Evidence ? it’s only an assumption) IE related cardiac failure (Raised systemic venous pressure to which pericardial veins drain) Local sepsis, Abcess formation tracks to pericardial space through transmural lymphatics Fungal , granulomatous , Tuberculous IE (Rare) Here IE and PE  share the same pathology Part of systemic sepsis activated Immune mechan...
Source: Dr.S.Venkatesan MD - January 28, 2020 Category: Cardiology Authors: dr s venkatesan Tags: cardiology -Therapeutics Cardiology -unresolved questions Infrequently asked questions in cardiology (iFAQs) pericardial disease pericardial effusion Pericardium infective endocarditis pericardial effusion in infective endocarditis Source Type: blogs

Guest Post from Howard Chang, MD, PhD: Unknown White Matter Disease
I am please to present a guest post from the illustriousDr. Howard Chang of Michigan State University, who presents a perplexing case. Dr. Chang would be interested in reader comments. He writes: "I can use some help from our colleagues.  Any advice (from anyone) on where and how to proceed for additional studies will be very much appreciated. "Dr. Howard ChangThis is a case of a 12-year-old male with cerebral palsy, severe developmental delay (level 1-2 years), and seizures (stable, no seizure episodes since 2 years). He had progressive decline in neurological functions following flu-like illness. He received IVIG an...
Source: neuropathology blog - October 5, 2016 Category: Radiology Tags: neuropathologists Source Type: blogs

Treatment Options In Goodpastures.
Goodpastures Syndrome. A rapidly progressive form of kidney disease associated with antibodies directed against the structural components of the functional subunits of the kidney and the lung. The disease therefore gives rise to both lung and kidney pathology a situation termed pulmonary renal syndrome. The exact cause is unknown. It is considered an autoimmune disorder (other autoimmune disorder’s that affect the kidney include Lupus Nephritis). The bodies own immune system is responsible for targeting both lung and kidney tissues. The initial immune system activation may occur in response to viral infection or even the...
Source: All Kidney News - September 29, 2015 Category: Urology & Nephrology Authors: jadhavbca Tags: Kidney News Treatment Options Source Type: blogs

New Treatments For FSGS -ASN Conference
Idiopathic focal and segmental glomerular sclerosis or FSGS is one of the most common causes of non diabetic kidney disease in the world and also one of the least satisfying to treat due to the difficulty with initiating and maintaining a durable remission. For decades the standard of treatment has been steroid therapy in high doses given either daily or every other day. This results in significant toxicity which includes the development of diabetes mellitus, osteoporosis, personality changes, weight gain, easy bruising etc. Yet these negative effects of steroid therapy are outweighed significantly by the result of not tre...
Source: All Kidney News - September 29, 2015 Category: Urology & Nephrology Authors: jadhavbca Tags: Kidney News FSGS TNF Source Type: blogs

New Treatments For FSGS -ASN Conference
Idiopathic focal and segmental glomerular sclerosis or FSGS is one of the most common causes of non diabetic kidney disease in the world and also one of the least satisfying to treat due to the difficulty with initiating and maintaining a durable remission. For decades the standard of treatment has been steroid therapy in high doses given either daily or every other day. This results in significant toxicity which includes the development of diabetes mellitus, osteoporosis, personality changes, weight gain, easy bruising etc. Yet these negative effects of steroid therapy are outweighed significantly by the result of not tre...
Source: All Kidney News - September 29, 2015 Category: Urology & Nephrology Authors: jadhavbca Tags: Kidney News FSGS TNF Source Type: blogs

Head Versus Heart: Do Passions Fuel Good MS Science or Drive Unrealistic Hopes?
This study will add steroid therapy to the use of high-pressure oxygen to examine its result on recovery from MS attacks. The current science on HBOT and multiple sclerosis stands as below: “HBOT is not a cure, but there is evidence to suggest some symptomatic benefit in a majority of patients and apparent stabilization or slowing of progression in a significant fraction (17 to 33%) of those who receive continuing therapy over a period of 10 years or longer. HBOT in MS has few side effects, mostly minor.”  -Richard A. Neubauer, M.D., Virginia Neubauer, and Sheldon F. Gottlieb, Ph.D. (Journal of American Physicians...
Source: Life with MS - February 10, 2014 Category: Other Conditions Authors: Trevis Gleason Tags: MS multiple sclerosis MS treatment multiple sclerosis clinical trials research Source Type: blogs

What Is Atrial Fibrillation?
Atrial Fibrillation is the most common abnormal heart rhythm. More than 5.1 million Americans are living with Atrial Fibrillation (Afib). As the Baby Boomers age, these numbers will increase and are expected to reach nearly 16 million by 2050.  September is Afib awareness month, take a few moments to learn about the symptoms and risk factors and be kind to your heart. Symptoms of Afib vary from patient to patient. Some people feel as if the heart will jump out of the chest, others have no symptoms at all. Patients describe symptoms feeling like: The heart skipping beats. Racing or thudding of the heart. Erratic heart bea...
Source: Embrace Your Heart Wellness Initiative - September 11, 2013 Category: Cardiology Authors: Eliz Greene Tags: Award Winning Blog Heart Health Answers.com arrythmia Atrial Fibrillation busy woman's guide to a healthy heart Mellanie True Hills StopAfib.org Source Type: blogs

Baby Girl Dies Hours After Getting 5 Vaccinations
CONCLUSION Interestingly, the OPV vaccinations were discontinued in the USA in 2000 because they were causing vaccine-associated paralytic polio. Rather than destroy these life-threatening vaccinations, these vaccines, along with many other discontinued and dangerous vaccines, were shipped over to the developing world to be used there. [5] Sickening, isn’t it? Not according to Bill Gates, who says that in six years polio will be wiped off the planet. He said: “We are on the verge of doing something we’ve never been able to do before—reaching the vast majority of children in the remotest places in the world.” ...
Source: vactruth.com - March 17, 2013 Category: Health Medicine and Bioethics Commentators Authors: Christina England Tags: Christina England Recent Articles Top Stories Bill Gates Paralysis Polio Vaccine Death Vaccine Safety vaccine schedule Source Type: blogs

Fwd: Neurological complications of influenza
Neurological complications of influenza Tsai JP, Baker AJ.  Neurocritical Care 18:2013; 118-130 (review article) There are five types of encephalopathy, two benign and three malignant.  Typically they occur a mean of two weeks post influenza, and are not associated with CNS inflammation.  They include:1)  MERS (mild encephalopathy with reversible splenial lesion)-   influenza symptoms, then prodrome of decreased level of consciousness, seizures, CSF pleocytosis, EEG abnormal, often within 103 days, and total resolution within one month with or without therapy.  Agents incl...
Source: neurologyminutiae - March 6, 2013 Category: Neurologists Source Type: blogs