Prophylactic abdominal drainage or no drainage after distal pancreatectomy (PANDORINA): a binational multicenter randomized controlled trial
The objective of the PANDORINA trial is to evaluate the non-inferiority of omitting routine intra-abdominal drainage after DP on postoperative morbidity (Clavien-Dindo score ≥ 3), and, secondarily, POPF grade B/C.Methods/designBinational multicenter randomized controlled non-inferiority trial, stratifying patients to high and low risk for POPF grade B/C and incorporating a standardized strategy for pancreatic transection. Two groups of 141 patients (282 in total) undergoing elective DP (either open or minimally invasive, with or without splenectomy). Primary outcome is postoperative rate of morbidity (Clavien-Dindo score...
Source: Trials - September 24, 2022 Category: Research Source Type: clinical trials
Ultrasound-guided Erector Spinae Plane Block Versus Paravertebral Block for Perioperative Analgesia in Patients Undergoing Open Splenectomy
Condition: Analgesia Interventions: Procedure: ultrasound guided erector spinae plane block; Procedure: ultrasound guided paravertebral block; Drug: conventional analgesia Sponsor: Ain Shams University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 7, 2022 Category: Research Source Type: clinical trials
The Effect of Laparoscopic Splenectomy on the Immune Function for Cirrhosis Patients
Conditions: Cirrhosis, Liver; Splenectomy; Status Intervention: Procedure: Laparoscopic splenectomy Sponsor: Yangzhou University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 21, 2022 Category: Research Source Type: clinical trials
