High-intensity Interval Training in Patients With Spinal Muscular Atrophy
Conditions: Spinal Muscular Atrophy Interventions: Behavioral: Exercise Sponsors: Rigshospitalet, Denmark Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

A Head-to-head Study Comparing the Functional Value of Two Models of Robotically Assisted Rehabilitation in SMA (Spinal Muscular Atrophy) Patients
Conditions: SMA Interventions: Procedure: Robotically Assisted Locomotion; Procedure: Robotically Assisted Verticalization Sponsors: Wiktor Dega University Orthopedic and Rehabilitation Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials

Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy
Conditions: Spinal Muscular Atrophy Interventions: Other: evaluation of muscle function; Other: First-line cognitive assessment; Other: second-line cognitive assessment; Other: Cardiac evaluation; Radiation: MRI; Other: Assessment of activity and muscle fatigue; Other: Assessment of bulbar function; Other: Evaluation of body composition and metabolism; Other: Questionnaires; Biological: Biocollection; Other: Skinfold measurement Sponsors: Hospices Civils de Lyon Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials

Spinal Muscular Atrophy Neonatal Screening Program
Conditions: Spinal Muscular Atrophy Interventions: Diagnostic Test: Screening SMA test Sponsors: IRCCS Burlo Garofolo Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb
Conditions: Spinal Muscular Atrophy; Spinal Muscular Atrophy Type 3; Spinal Muscular Atrophy Type II; Spinal Muscular Atrophy 4; SMA Interventions: Device: Spinal Cord Stimulator (Octopolar Medtronic Vectris Leads) Sponsors: Marco Capogrosso; Roche-Genentech Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials

An Open Label Study of Gene Therapy Product in Spinal Muscular Atrophy Patients
Conditions: Spinal Muscular Atrophy Interventions: Drug: vesemnogene lantuparvovec Sponsors: Lantu Biopharma Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials

Assessing the Fertility Status of Men With Spinal Muscular Atrophy (SMA)
Conditions: Fertility Issues Sponsors: Bar-Chama, Natan, M.D. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 8, 2024 Category: Research Source Type: clinical trials

A Clinical Study Evaluating the Safety and Efficacy of SKG0201 Injection in Patients With Spinal Muscular Atrophy Type 1
Conditions: Spinal Muscular Atrophy 1 Interventions: Genetic: SKG0201 Injection Sponsors: Kun Sun Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials

Real-World Use of Novel Treatments in Patients With Spinal Muscular Atrophy (SMA): A Multi-Site Retrospective Chart Review of Pediatric SMA Patients Outside of the United States
Conditions: Spinal Muscular Atrophy Sponsors: Novartis Pharmaceuticals Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 21, 2023 Category: Research Source Type: clinical trials

Two Different Treatment Modalities in Patients With Spinal Muscular Atrophy
Conditions: Muscular Atrophy, Spinal Interventions: Other: Pulmonary Rehabilitation; Other: Trunk Control Training Sponsors: Istanbul Medipol University Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 21, 2023 Category: Research Source Type: clinical trials

Safety and Usability of a Robotic Gait Device for Children and Adolescents With Neurological or Neuromuscular Disease in Their Natural Environment
Conditions: Cerebral Palsy; Acquired Brain Injury; Spinal Muscular Atrophy Interventions: Device: EXPLORER Sponsors: MarsiBionics; Hospital Infantil Universitario Ni ño Jesús, Madrid, Spain; Hospital Universitario La Paz; Hospital Universitario 12 de Octubre; Hospital General Universitario Gregorio Marañon Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials

Test of Aquatic Mobility of SMA Infants
Conditions: Infantile Spinal Muscular Atrophy Interventions: Other: Mobility study in dry conditions; Other: Mobility study in water conditions Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 30, 2023 Category: Research Source Type: clinical trials

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
Conditions: Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, Including; Sickle Cell Disease; Cystic Fibrosis; Fragile X Syndrome; Proximal Spinal Muscular Atrophy; Myotonic Dystrophy; Muscular Dystrophy, Duchenne; Muscular Dystrophy, Becker; Neurofibromatosis-Noonan Syndrome; Huntington Disease; Hemophilia A; Hemophilia B; MODY2 Diabetes; X-Linked Hydrocephalus; Autosomal Recessive Polycystic Kidney Disease Interventions: Biological: Blood sample Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2023 Category: Research Source Type: clinical trials

Spinal Cord Gray Matter Imaging in Spinal Muscular Atrophy
Conditions: Spinal Muscular Atrophy Type III; Spinal Muscular Atrophy Type II Interventions: Diagnostic Test: MRI Sponsors: University Hospital, Basel, Switzerland Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 17, 2023 Category: Research Source Type: clinical trials

NMD Pharma initiates Phase II trial of NMD670 in Spinal Muscular Atrophy
Aarhus, Denmark, 26 September 2023– NMD Pharma A/S, a clinical-stage biotech company developing first-in-class, small molecule ClC-1 inhibitors directly targeting muscle function within neuromuscular disorders, today announces that the first... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 26, 2023 Category: Pharmaceuticals Source Type: clinical trials