Fight Aging! Newsletter, March 21st 2022
This study was the first to examine how these networks interact with physical activity and fitness to impact how the brain functions. "This paper is exciting because it gives us some evidence that when people whose brain networks aren't functioning optimally engage in physical activity, we see improvement in their executive function and their independence. Maybe just take the stairs on the way to work. Stand up and walk around a little bit more. That's where you get the most bang for your buck, not crazy, high-intensity exercise." Variations in Biological Age Across Organs in Younger Individuals https:/...
Source: Fight Aging! - March 20, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Treating Obstructive Sleep Apnea Reduces Epigenetic Age Acceleration
Now that cost-effective epigenetic age assessment is a going concern, we will see all sorts of interesting correlations, such as the one noted here in patients with obstructive sleep apnea, before and after treatment. Since it remains unclear as to what exactly is being measured by epigenetic age, which aspects of aging and consequent metabolic dysfunction contribute to the outcome, a good deal of speculation is involved when thinking about why and how what is known of the consequences of sleep apnea relates to what is known of degenerative aging. Obstructive sleep apnea (OSA) affects 22 million people in the U.S....
Source: Fight Aging! - March 16, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A man in his 60s with syncope. In syncope, what are we looking for on the ECG, and why?
 Submitted and written by Rachel Plate M.D., with some edits by Smith and Meyers A man in his 60s with history of type 2 diabetes, obesity, obstructive sleep apnea requiring nightly CPAP, and hypertension presented for evaluation following a witnessed syncopal episode at home. The patient noted this occurred after standing and he did have prodromal symptoms including lightheadedness. EKG was obtained and shown below.What do you think?  The ECG shows sinus rhythm a bifascicular block, both a right bundle branch block and a left anterior fascicular block. The P waves are hard to discern with the artifact ...
Source: Dr. Smith's ECG Blog - January 28, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

O2Ring Keeps an Eye on Your Blood Oxygen Level: A Medgadget Review
Conclusion We found O2Ring to be a convenient, easy-to-use pulse oximeter. It is a particularly appealing option for medical conditions that require prolonged monitoring of blood oxygen levels, such as sleep apnea, chronic lung disease, and more recently, COVID-19 pneumonia. O2Ring can be purchased from Wellue’s official website and Amazon. It retails for $165, which is slightly above the price point of other comparable products. Nevertheless, the device may offer peace of mind to both users and their loved ones. Product page: O2Ring Oximeter Continuous Ring Oxygen Monitor Related flashbacks: Smart Ring ...
Source: Medgadget - December 27, 2021 Category: Medical Devices Authors: Kenan Raddawi Tags: Cardiology Diagnostics Exclusive Sports Medicine Source Type: blogs

Six guidelines to navigate the Aduhelm controversy and (hopefully) help patients with Mild Cognitive Impairment and early-stage Alzheimer ’s Disease
The approval of a controversial new drug for Alzheimer’s disease, Aduhelm, is shining a spotlight on mild cognitive impairment — problems with memory, attention, language or other cognitive tasks that exceed changes expected with normal aging. After initially indicating that Aduhelm could be prescribed to anyone with dementia, the Food and Drug Administration now specifies that the prescription drug be given to individuals with mild cognitive impairment or early-stage Alzheimer’s, the groups in which the medication was studied. Yet this narrower recommendation raises questions. What does a diagnosis of mild cognitive...
Source: SharpBrains - October 13, 2021 Category: Neuroscience Authors: Kaiser Health News Tags: Brain/ Mental Health Aduhelm Alzheimer’s Disease attention-problems brain bleeding brain swelling cognitive problems dementia dementia specialists early-stage Alzheimer’s Food and Drug Administration language problems memory pr Source Type: blogs

Dental appliances for sleep apnea: Do they work?
Keeping your partner — or yourself — up at night with loud snoring? This might be more than a nuisance. About 25% of men and nearly 10% of women have obstructive sleep apnea (OSA), a serious sleep disorder characterized by explosive snores, grunts, and gasps. Tissue at the back of the throat temporarily obstructs the airway, leading to breathing pauses (apneas) throughout the night. Not only does OSA leave people tired and groggy, but it also puts them at risk for a host of health problems, including high blood pressure, depression, and heart disease. The most effective and best-studied treatment is positive airway pre...
Source: Harvard Health Blog - April 28, 2021 Category: Consumer Health News Authors: Julie Corliss Tags: Dental Health Fatigue Hypertension and Stroke Sleep Source Type: blogs

Fight Aging! Newsletter, April 19th 2021
In conclusion, airway pressure treatment and adherence are independently associated with lower odds of incident AD diagnoses in older adults. Results suggest that treatment of OSA may reduce risk of subsequent dementia. (Source: Fight Aging!)
Source: Fight Aging! - April 18, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Treating Sleep Apnea Lowers Dementia Risk By 20-30%
In conclusion, airway pressure treatment and adherence are independently associated with lower odds of incident AD diagnoses in older adults. Results suggest that treatment of OSA may reduce risk of subsequent dementia. Link: https://doi.org/10.1093/sleep/zsab076 (Source: Fight Aging!)
Source: Fight Aging! - April 16, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

“I Don’t Do Windows” Says the Maid. “I Don’t Do Machines” Says this Doctor – “But I Do Nudge Therapy”
By HANS DUVEFELT The hackneyed windows phrase, about what a domestic employee will and will not do for an employer, represents a concept that applies to the life of a doctor, too. Personally, I have to do Windows, the default computer system of corporate America, even though I despise it. But in my personal life I use iOS on my iPad and iPhone and very rarely use even my slick looking MacBook Pro. I use “tech” and machines as little as possible and I prefer that they work invisibly and intuitively. In medicine, even in what used to be called “general practice”, you can’t very reasonably do everything for...
Source: The Health Care Blog - March 29, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care Hans Duvefelt Source Type: blogs

Phenogroups in heart failure with preserved ejection fraction
Clustering analysis of heart failure with preserved ejection fraction (HFpEF) has been used to define three distinct phenogroups by Shah SJ et al [1]. They used dense phenotypic data for “phenomapping”. They prospectively studied 397 HFpEF patients with clinical, laboratory and echocardiographic data. Several statistical algorithms were used to define and characterize mutually exclusive phenogroups of HFpEF. By phenomapping analysis they arrived at 3 distinct phenogroups with markedly different clinical characteristics, cardiac function, invasive hemodynamic patterns and outcome. There were different characte...
Source: Cardiophile MD - March 8, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Intraoral Stimulation for Obstructive Sleep Apnea: Interview with Akhil Tripathi, CEO of Signifier Medical
Signifier Medical Technologies, a company with headquarters in London, UK and Massachusetts, has created a new treatment for obstructive sleep apnea, and it is the first to be used during waking hours. Unlike conventional sleep apnea devices, the eXciteOSA is designed to be used for short periods during the day and employs electrical stimulation to improve tongue muscle function, helping keep the airway open during sleep. It was recently authorized for sale by the FDA. Sleep apnea involves airway obstruction during sleep and can have a variety of serious consequences, including cancer and cardiovascular disease....
Source: Medgadget - February 24, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Exclusive Medicine Neurology Source Type: blogs

Neuromuscular Tongue Stimulator for Snoring Authorized by FDA
Obstructive sleep apnea (OSA) impacts millions of people with wide-ranging effects that can have a serious impact on overall health. There are a number of technologies to help manage and sometimes treat the condition, including continuous positive airway pressure (CPAP) devices. Most patients end up receiving therapies that don’t treat the underlying causes of poor breathing during sleep. The FDA has now authorized, via the De Novo process, the first device that trains the muscles around the tongue to become stronger in order to reduce snoring and help alleviate OSA. Signifier Medical Technologies, a compan...
Source: Medgadget - February 9, 2021 Category: Medical Devices Authors: Medgadget Editors Tags: Cardiology Medicine Neurology Source Type: blogs

The Art of Prescribing (Or Not)
By HANS DUVEFELT I have learned a few things about prescribing medications during my 42 years as a physician. Some are old lessons, and some are more recent. I thought I’d share some random examples. First: I don’t like to have to use medications, but when they seem necessary, I choose, present and prescribe them with great care. CHOOSING MEDICATIONS Medications are like people. They have personalities. With so many choices for any given diagnosis or symptom, I consider their mechanism of action, possible beneficial additional effects and their risk of unwanted side effects when selecting which one to presc...
Source: The Health Care Blog - February 1, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Primary Care Hans Duvefelt Source Type: blogs

Medical Gadgets at This Year ’s CES 2021
CES 2021 took place this past week, but due to the ongoing COVID-19 pandemic, the annual electronics megashow show was completely virtual. While we certainly missed the free swag, a chance with lady luck at the Vegas casino tables, and the opportunity to reunite with many of you Medgadget readers, there were still a good deal of medical and health technology announcements this year. Here’s a round-up of some of the notable products we encountered. Masks Everywhere In the age of COVID-19, face coverings have become a hot medical gadget and a new fashion trend. We saw no shortage of masks of all sorts while roami...
Source: Medgadget - January 18, 2021 Category: Medical Devices Authors: Scott Jung Tags: Cardiology Exclusive OTC ces Source Type: blogs