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A Mixture of < em > Morus alba < /em > and < em > Angelica keiskei < /em > Leaves Extracts Improves Muscle Atrophy by Activating the PI3K/Akt/mTOR Signaling Pathway and Inhibiting FoxO3a In Vitro and In Vivo
J Microbiol Biotechnol. 2023 Aug 25;33(12):1-10. doi: 10.4014/jmb.2306.06012. Online ahead of print.ABSTRACTMuscle atrophy, which is defined as a decrease in muscle mass and strength, is caused by an imbalance between the anabolism and catabolism of muscle proteins. Thus, modulating the homeostasis between muscle protein synthesis and degradation represents an efficient treatment approach for this condition. In the present study, the protective effects against muscle atrophy of ethanol extracts of Morus alba L. (MA) and Angelica keiskei Koidz. (AK) leaves and their mixtures (MIX) were evaluated in vitro and in vivo. Our re...
Source: Journal of Microbiology and Biotechnology - September 7, 2023 Category: Biotechnology Authors: Hyun Hwangbo Min Yeong Kim Seon Yeong Ji Da Hye Kim Beom Su Park Seong Un Jeong Jae Hyun Yoon Tae Hee Kim Gi-Young Kim Yung Hyun Choi Source Type: research
Effects of Pre-Hospital Dexamethasone Administration on Outcomes of Patients with COPD and Asthma Exacerbation; a Cross-Sectional Study
CONCLUSION: The dexamethasone administration by EMS in pre-hospital setting for management of asthma and COPD patients is beneficial in reducing the ED-LOS and need for hospital admission but its effects are not statistically significant, except regarding the ED-LOS of asthma exacerbation cases.PMID:37671276 | PMC:PMC10475744 | DOI:10.22037/aaem.v11i1.2037
Source: Accident and Emergency Nursing - September 6, 2023 Category: Emergency Medicine Authors: Thongpitak Huabbangyang Agasak Silakoon Chunlanee Sangketchon Jareeda Sukhuntee Jukkit Kumkong Tanut Srithanayuchet Parinya Chamnanpol Theeraphat Meechai Source Type: research
Anorexia Nervosa and Adrenal Hormones: A Systematic Review and Meta-analysis
CONCLUSIONS: Women with anorexia nervosa have higher cortisol levels and lower DHEA-S and testosterone levels compared to women without anorexia nervosa. This finding is important to consider when evaluating low-weight women for disorders involving the adrenal axis, especially Cushing's syndrome.PMID:37669399 | DOI:10.1093/ejendo/lvad123
Source: European Journal of Endocrinology - September 5, 2023 Category: Endocrinology Authors: Subhanudh Thavaraputta Patompong Ungprasert Selma F Witchel Pouneh K Fazeli Source Type: research
