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E-115 Identifying cognitive dysfunction after aneurysmal subarachnoid hemorrhage
ConclusionA brief, peer-led education session on cognitive dysfunction after aSAH improves knowledge of the problem and current recommendations in the literature for cognitive dysfunction after aSAH. Ongoing research is necessary to understand whether the education session and observed positive knowledge change translate to a change in practice and compliance with evidence-based recommendations for cognitive dysfunction screening after aSAH.Disclosures N. Hall: None. R. Chitale: None. M. Fusco: None. M. Froehler: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Hall, N., Chitale, R., Fusco, M., Froehler, M. Tags: Electronic poster abstracts Source Type: research

A systematic review of non-drug interventions to prevent and treat anxiety in people with aphasia after stroke
CONCLUSION: Definitive conclusions about the effectiveness of non-drug interventions for the prevention and/or treatment of anxiety in people with aphasia post-stroke cannot be made. Interventions that may show promise for those with aphasia and symptoms of anxiety include mindfulness meditation, modified cognitive behaviour therapy, unilateral nostril breathing, and the "Enhance Psychological Coping after Stroke" programme. Further high-quality research with better reporting of the inclusion of participants with aphasia and their specific sub-group results are required.Implications for RehabilitationIt is important for re...
Source: Disability and Rehabilitation - June 12, 2021 Category: Rehabilitation Authors: Brooke J Ryan Stephanie M Clunne Caroline J Baker Ciara Shiggins Miranda L Rose Ian I Kneebone Source Type: research

Treatment of Post-Stroke Depression
We present the reader with the most recent evidence to support pharmacological, psychosocial, and neuromodulation interventions in PSD. We also discuss the relevance of using antidepressants and psychotherapy to prevent PSD and discuss evidence that antidepressant treatment may reduce mortality after stroke.Recent findingsNeuroinflammation and decrease neurogenesis and plasticity may play an important role in the mechanism of PSD. The strongest predictors of PSD are stroke severity, early physical disability, and severity of loss of functioning. Nevertheless, populations at risk for PSD are yet to be identified. Recent met...
Source: Current Treatment Options in Neurology - June 24, 2019 Category: Neurology Source Type: research

Randomised, waiting list controlled trial of cognitive-behavioural therapy for persistent postconcussional symptoms after predominantly mild-moderate traumatic brain injury
Conclusions This study suggests that CBT can improve quality of life for adults with persistent PCS and potentially reduce symptoms for some, in the context of outpatient brain injury rehabilitation services. Trial registration number ISRCTN49540320.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 12, 2016 Category: Neurosurgery Authors: Potter, S. D. S., Brown, R. G., Fleminger, S. Tags: Dementia, Neurological injury, Stroke, Trauma CNS / PNS, Anxiety disorders (including OCD and PTSD), Memory disorders (psychiatry), Trauma, Injury Neuropsychiatry Source Type: research

Prefrontal Cortex Stroke Induces Delayed Impairment in Spatial Memory.
Abstract Stroke is the leading cause of long-term disability. Little is known about the effects of stroke on cognitive deficits. The subtle nature of cognition and its respective domains in areas such as working memory and attention can make this difficult to diagnose and treat. We aimed to establish a model of focal ischemia that targets the prefrontal cortex (PFC) and induce memory impairments. Stroke and sham mice were assessed at one and four-weeks post-stroke on various tests: open-field task to assess activity; grid-walk and cylinder task to assess motor impairments; elevated plus maze to assess anxiety; nov...
Source: Behavioural Brain Research - August 22, 2015 Category: Neurology Authors: Zhou LY, Wright TE, Clarkson AN Tags: Behav Brain Res Source Type: research