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Procedure: Perfusion

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Total 16 results found since Jan 2013.

Reduction of scan duration and radiation dose in cerebral CT perfusion imaging of acute stroke using a recurrent neural network
This study suggests that a recurrent VAE-GAN could potentially be used to predict a portion of CTP frames from truncated acquisitions, preserving the majority of clinical content in the images, and potentially reducing the scan duration and radiation dose simultaneously by 65% and 54.5%, respectively. &#xD.PMID:37327792 | DOI:10.1088/1361-6560/acdf3a
Source: Physics in Medicine and Biology - June 16, 2023 Category: Physics Authors: Mahdieh Dashtbani Moghari Amirhossein Sanaat Noel Young Krystal Moore Habib Zaidi Andrew Evans Roger R Fulton Andre Z Kyme Source Type: research

Towards quantitative digital subtraction perfusion angiography: An animal study
CONCLUSIONS: In comparison to TIC-derived parameters, deconvolution-based perfusion imaging in DSA shows significantly higher quantitative reliability against variations in injection protocols across different time resolutions, and is sensitive to alterations in cerebral hemodynamics. The quantitative nature of perfusion angiography may allow for objective treatment assessment in neurovascular interventions.PMID:37222210 | DOI:10.1002/mp.16473
Source: Health Physics - May 24, 2023 Category: Physics Authors: Ruisheng Su P Matthijs van der Sluijs Joaquim Bobi Aladdin Taha Heleen M M van Beusekom Aad van der Lugt Wiro J Niessen Danny Ruijters Theo van Walsum Source Type: research

Noise modelling of perfusion CT images for robust hemodynamic parameter estimations
This study first investigates the noise properties in low-dose CPCT images and proposes a perfusion deconvolution model based on the noise properties.APPROACH: To characterize the noise distribution in CPCT images properly, we analyze noise properties in low-dose CPCT images and find that the intra-frame noise distribution may vary in the different areas and the inter-frame noise also may vary in low-dose CPCT images. Thus, we attempt the first-ever effort to model CPCT noise with a non-independent and identical distribution (i.i.d.) mixture-of-Gaussians (MoG) model for noise assumption. Furthermore, we integrate the noise...
Source: Physics in Medicine and Biology - May 6, 2022 Category: Physics Authors: Sui Li Dong Zeng Zhaoying Bian Jianhua Ma Source Type: research

Learning non-local perfusion textures for high-quality computed tomography perfusion imaging
CONCLUSIONS: The presented NPTN method can obtain high-quality CTP images and estimate high-accuracy CBF map by characterizing more structure details and contrast variants in the CTP image, and outperform the competing methods at low-dose cases.PMID:33910178 | DOI:10.1088/1361-6560/abfc90
Source: Physics in Medicine and Biology - April 28, 2021 Category: Physics Authors: Sui Li Dong Zeng Zhaoying Bian Danyang Li Manman Zhu Jing Huang Jianhua Ma Source Type: research

Efficient radiation dose reduction in whole-brain CT perfusion imaging using a 3D GAN: Performance and clinical feasibility
Phys Med Biol. 2021 Feb 23. doi: 10.1088/1361-6560/abe917. Online ahead of print.ABSTRACTDose reduction in cerebral CT perfusion (CTP) imaging is desirable but is accompanied by an increase in noise that can compromise the image quality and the accuracy of image-based haemodynamic modelling used for clinical decision support in acute ischaemic stroke. The few reported methods aimed at denoising low-dose CTP images lack practicality by considering only small sections of the brain or being computationally expensive. Moreover, the prediction of infarct and penumbra size and location - the chief means of decision support for t...
Source: Physics in Medicine and Biology - February 23, 2021 Category: Physics Authors: Mahdieh Dashtbani Moghari Luping Zhou Biting Yu Noel Young Krystal Moore Andrew Evans Roger R Fulton Andre Z Kyme Source Type: research

Optimized sampling for high resolution multi-pinhole brain SPECT with stationary detectors.
Abstract Brain perfusion SPECT can be used in the diagnosis of various neurologic or psychiatric disorders, e.g. stroke, epilepsy, dementia and posttraumatic stress disorder. As traditional SPECT provides limited resolution and sensitivity, we recently proposed a high resolution focusing multi-pinhole clinical SPECT scanner dubbed G-SPECT-I (Beekman et al 2015). G-SPECT-I achieves data completeness in the scan region of interest by making small translations of the patient bed while using projections from all bed positions together for image reconstruction. A strategy to restrict the number of bed translations is d...
Source: Physics in Medicine and Biology - November 25, 2019 Category: Physics Authors: Chen Y, Goorden MC, Vastenhouw B, Beekman FJ Tags: Phys Med Biol Source Type: research

Development of a globally optimised model of the cerebral arteries.
Abstract The cerebral arteries are difficult to reproduce from first principles, featuring interwoven territories, and intricate layers of grey and white matter with differing metabolic demand. The aim of this study was to identify the ideal configuration of arteries required to sustain an entire brain hemisphere based on minimisation of the energy required to supply the tissue. The 3D distribution of grey and white matter within a healthy human brain was first segmented from magnetic resonance images. A novel simulated annealing algorithm was then applied to determine the optimal configuration of arteries require...
Source: Physics in Medicine and Biology - June 20, 2019 Category: Physics Authors: Keelan J, Chung EML, Hague JP Tags: Phys Med Biol Source Type: research

Quantitative analysis of regional endocardial geometry dynamics from 4D cardiac CT images: endocardial tracking based on the iterative closest point with an integrated scale estimation.
Abstract Regional cardiac function analysis is important for the diagnosis and treatment planning of ischemic heart disease, but has not been sufficiently developed in the field of computed tomography (CT). Therefore, we propose a three-dimensional endocardial tracking framework for cardiac CT using local point cloud registration based on the iterative closest point with an integrated scale estimation algorithm. We also introduce regional function descriptors that express the curvature and stretching of the endocardium: Surface distortion (E) and Scaling rate (S). For a region-to-region comparison, we propose endo...
Source: Physics in Medicine and Biology - January 22, 2019 Category: Physics Authors: Kobayashi K, Wakasa S, Sato K, Kanai S, Date H, Kimura S, Oyama-Manabe N, Matsui Y Tags: Phys Med Biol Source Type: research