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Specialty: Transplant Surgery

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Total 557 results found since Jan 2013.

Does conventional intra-aortic balloon pump trigger timing produce optimal hemodynamic effects in vivo?
CONCLUSIONS: In our experiments, neither a single frequency nor a single inflation/deflation timing, including conventional IAB timing, has shown superiority by uniformly benefiting all studied hemodynamic parameters. A choice of optimal frequency and IAB timing might need to be made based on individual patient hemodynamic needs rather than as a generalized protocol. PMID: 25744191 [PubMed - as supplied by publisher]
Source: The International Journal of Artificial Organs - March 1, 2015 Category: Transplant Surgery Authors: Kolyva C, Pantalos GM, Pepper JR, Khir AW Tags: Int J Artif Organs Source Type: research

Biventricular failure with low pulmonary vascular resistance was managed by left ventricular assist device alone without right-sided mechanical support
Abstract How to manage preoperative right ventricular dysfunction (RVD) in heart failure patients without cardiogenic shock remains as a matter to be debated because implantable biventricular assist device treatment has not been established thus far. We here presented a patient with significant RVD indicated by low RV stroke work index (0.3 g/m) and RV dilatation as well as low pulmonary vascular resistance (PVR, 0.8 Wood Unit), who was managed by the introduction of pimobendan and sildenafil after the implantation of DuraHeart and tricuspid annuloplasty without right VAD, although his New York Heart Association ...
Source: Journal of Artificial Organs - March 13, 2015 Category: Transplant Surgery Source Type: research

“Framingham score, renal dysfunction and cardiovascular risk in liver transplant patients”
Conclusions: In our series, the FRS and eGFR at LT were able to predict the development of post‐LT CV events and poor outcome. This article is protected by copyright. All rights reserved.
Source: Liver Transplantation - March 30, 2015 Category: Transplant Surgery Authors: Tommaso Di Maira, Angel Rubin, Lorena Puchades, Victoria Aguilera, Carmen Vinaixa, Maria Garcia, Nicola De Maria, Erica Villa, Rafael Lopez‐Andujar, Fernando San Juan, Eva Montalva, Judith Perez, Martin Prieto, Marina Berenguer Tags: Original Articles Source Type: research

Circulating Histone-Induced Lung Injury: A Novel Model of Damaged Lungs From Brain-Dead Donors
Histones, a component of nucleosomes, are released from dying cells into the blood circulation in patients with stroke. It has been also known that circulating histones can cause endothelial injury of the pulmonary vasculature. We hypothesized that a transient release of histones in the circulation cause endothelial damages in the brain-dead donor lungs that can lead severe re-perfusion injury after lung transplantation.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: T. Murayama, M. Anraku, T. Murakawa, T. Yoshioka, M. Inui, N. Hiyama, M. Kawashima, T. Tsuchiya, J. Ichinose, H. Hino, K. Nagayama, J. Nitadori, K. Kakimi, J. Nakajima Source Type: research

Left Ventricular Assist Devices vs. the Total Artificial Heart: Which Causes More Cerebrovascular Accidents?
More recently, the continuous flow left ventricular assist devices (LVADs) have been more commonly used in patients (pts) with severe left heart failure. However, these devices also have risk for strokes, both ischemic and hemorrhagic. The Total Artificial Heart (TAH) has also been used in patients with biventricular heart failure at our single institution. Both continuous flow LVADs and TAH patients are systemically anti-coagulated with warfarin and aspirin. We sought to compare stroke rates between the LVAD patients and TAH pts.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: C. Runyan, F. Arabia, L. Czer, M. Kittleson, E. Passano, F. Liou, J. Yabuno, H. Henry, D.H. Chang, J. Kobashigawa, J. Moriguchi Source Type: research

Effect of Preoperative Atrial Fibrillation on Clinical Outcomes After Continuous Flow-Left Ventricular Assist Device Therapy
Atrial fibrillation (AF) is the most common chronic cardiac arrhythmia, often found in patients with heart failure requiring a ventricular assist device. Our goal was to assess the effect of preoperative AF on the risk of thromboembolic (TE) events (hemolysis, stroke and/or TIA), clinical outcomes and survival in patients receiving a continuous-flow left ventricular assist device (CF-LVAD).
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: E. Lushaj, S. Akhter, T. Kohmoto, L. Lozonschi, M. Murray, S. Osaki Source Type: research

Temporal Distribution of Hematologic Complications During Berlin EXCOR Support
The Berlin Heart EXCOR trial demonstrated a high incidence of bleeding complications and stroke. Little is known, however, with regards to the timing of these events. The purpose of this study is to describe a single center experience with the Berlin EXCOR VAD, with a particular focus on the temporal distribution of these mutually related complications.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: S. Burki, D.H. Mahoney, A. Jeewa, W. Zhang, E. McKenzie, D.L. Morales, C.M. Mery, J.S. Heinle, C.D. Fraser, I. Adachi Source Type: research

Thromboelastography/Platelet Mapping® and Aspirin: Is There Evidence of a Meaningful Dose-Response Relationship in Children Supported With the Berlin Heart EXCOR Ventricular Assist Device?
Thromboelastography with Platelet Mapping® (TEG/PM) is widely used to adjust the dose of Aspirin (ASA) for children supported with the Berlin Heart EXCOR Pediatric Ventricular Assist Device (VAD). The use of TEG/PM is controversial in part because stroke remains a common occurrence and TEG/PM has never been validated for this purpose. We sought to determine whether there is a meaningful correlation between the dose of ASA and the TEG/PM ‘percent arachadonic acid (%AA) inhibition’ value in children supported with the EXCOR.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: L.J. May, C. Lo, T.M. Tesoro, J.L. Zehnder, S. Chen, J. Lee, M. Desai, D.B. McElhinney, D.N. Rosenthal, K. Maeda, C.S. Almond Source Type: research

Fortuity or Causality in Minimally Invasive LVAD Implantation: Relation Between Outflow Graft Height of Implantation Along the Ascending Aorta and Cerebral Ischemic Events
To evaluate whether the site of implantation of the outflow-graft on the ascending aorta is related to the incidence of cerebral ischemic stroke events in patients undergoing minimally-invasive-LVAD-implantation.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: J. Bejko, T. Bottio, G. Bortolussi, M. Gallo, R. Bianco, V. Tarzia, A. Guariento, G. Gerosa Source Type: research

Percutaneous Driveline Infection Does Not Increase Subsequent Risk of Stroke and Pump Thrombus During Support With a Left Ventricular Assist Device
Percutaneous driveline infections (DLI) pose significant risk in patients supported with a left ventricular assist device (LVAD). While INTERMACS data suggests increased incidence of thromboembolic complications in close proximity following DLI, no study has specifically examined this association in a time-dependent manner and analyzed risk of subsequent events. We reviewed the Mechanical Circulatory Support (MCS) Research Network registry.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: J. Van Meeteren, S. Maltais, S. Dunlay, N. Haglund, M.E. Davis, F.D. Pagani, K. Aaronson, J. Cowger, P. Shah, J.M. Stulak Source Type: research

Temporal Differences in Adverse Event Rates in Patients Bridged With the HeartWare Left Ventricular Assist Device
Left ventricular assist devices (LVAD) have significantly improved survival and quality of life in patients with advanced heart failure. However, these devices are associated with significant adverse events (AEs), particularly bleeding, infection, stroke and right heart failure. We sought to evaluate temporal differences in AE rates in patients bridged to transplantation.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: S. Maltais, K.D. Aaronson, J.J. Teuteberg, M.S. Slaughter, S.S. Najjar, V. Jeevanandam, D.T. Pham, E.C. McGee, K. Najarian, R.L. Kormos Source Type: research

Driveline Infection Is Not Associated With Increased Risk of Thrombotic Events in CF-LVAD Patients
It has been debated whether anti-thrombotic therapy should be adjusted in the setting of driveline infection (DLI) as infection may lead to a pro-inflammatory state associated with platelet activation and increased risk of thrombotic complications. The aim of this study was to examine the relationship of DLI and thrombotic complications, notably stroke and device thrombosis (DT), in patients with continuous-flow LVADs.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: J. Fried, B. Cagliostro, A. Levin, O. Wever-Pinzon, A.R. Garan, R. Te-Frey, K.O. Ronquillo, K. Takeda, H. Takayama, M. Yuzefpolskaya, D.M. Mancini, Y. Naka, P.C. Colombo, V. Topkara Source Type: research

A Microcontroller Platform for the Rapid Prototyping of Functional Electrical Stimulation‐Based Gait Neuroprostheses
Abstract Functional electrical stimulation (FES) has been used over the last decades as a method to rehabilitate lost motor functions of individuals with spinal cord injury, multiple sclerosis, and post‐stroke hemiparesis. Within this field, researchers in need of developing FES‐based control solutions for specific disabilities often have to choose between either the acquisition and integration of high‐performance industry‐level systems, which are rather expensive and hardly portable, or develop custom‐made portable solutions, which despite their lower cost, usually require expert‐level electronic skills. Here,...
Source: Artificial Organs - April 1, 2015 Category: Transplant Surgery Authors: Paulo Luzio de Melo, Miguel Tavares da Silva, Jorge Martins, Dava Newman Tags: Main Text Article Source Type: research

Clinical Outcomes of Patients Treated With Pulmonary Vasodilators Early and in High Dose After Left Ventricular Assist Device Implantation
Abstract Right ventricular failure (RVF) is common after left ventricular assist device (LVAD) implantation and a major determinant of adverse outcomes. Optimal perioperative right ventricular (RV) management is not well defined. We evaluated the use of pulmonary vasodilator therapy during LVAD implantation. We performed a retrospective analysis of continuous‐flow LVAD implants and pulmonary vasodilator use at our institution between September 2004 and June 2013. Preoperative RVF risk was assessed using recognized variables. Sixty‐five patients (80% men, 50 ± 14 years) were included: 52% HeartWare ventricular assi...
Source: Artificial Organs - May 1, 2015 Category: Transplant Surgery Authors: Christopher Critoph, Gillian Green, Helen Hayes, Jay Baumwol, Kaitlyn Lam, Robert Larbalestier, Sharon Chih Tags: Thoughts and Progress Source Type: research

Framingham score, renal dysfunction, and cardiovascular risk in liver transplant patients
Cardiovascular (CV) events represent major impediments to the long‐term survival of liver transplantation (LT) patients. The aim of this study was to assess whether the Framingham risk score (FRS) at transplantation can predict the development of post‐LT cardiovascular events (CVEs). Patients transplanted between 2006 and 2008 were included. Baseline features, CV risk factors, and CVEs occurring after LT (ischemic heart disease, stroke, heart failure, de novo arrhythmias, and peripheral arterial disease) were recorded. In total, 250 patients (69.6% men) with a median age of 56 years (range, 18‐68 years) were included...
Source: Liver Transplantation - May 26, 2015 Category: Transplant Surgery Authors: Tommaso Di Maira, Angel Rubin, Lorena Puchades, Victoria Aguilera, Carmen Vinaixa, Maria Garcia, Nicola De Maria, Erica Villa, Rafael Lopez‐Andujar, Fernando San Juan, Eva Montalva, Judith Perez, Martin Prieto, Marina Berenguer Tags: Original Article Source Type: research