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Specialty: Transplant Surgery
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Total 557 results found since Jan 2013.
Huge thrombus formation in the left ventricle during bilateral CentriMag ventricular assist device with successful bridging to heart transplantation: a case report and review of the literature
AbstractOwing to shortage of donor hearts, the ventricular assist device is used as a bridging therapy to heart transplantation. However, thrombus formation is a critical complication during ventricular assist device circulatory support that might result in ischemic infarction of end organs. Here, we report a patient diagnosed with decompensated dilated cardiomyopathy and cardiogenic shock who underwent emergent extracorporeal life support, and subsequent temporary bilateral ventricular assistance with the CentriMag device (Levitronix LLC, Waltham, MA). Daily transthoracic echocardiography did not detect any thrombus forma...
Source: Journal of Artificial Organs - July 13, 2020 Category: Transplant Surgery Source Type: research
A Comparative Analysis of Long-Term Outcomes in the MOMENTUM 3 Pivotal Trial and Continued Access Protocol Post-Approval Study Phase: A Study of over 1500 HeartMate 3 Implants
The MOMENTUM 3 pivotal trial conducted from 2014 to 2018 evaluated safety and effectiveness of the HeartMate 3 (HM3) left ventricular assist system (LVAS) compared to the HeartMate II pump. The trial demonstrated superiority of the HM3 LVAS for the primary endpoint of survival free of disabling stroke or reoperation to replace a malfunctioning pump at 2-years. HM3 LVAS superiority was due to improved hemocompatibility with near-elimination of device thrombosis, halving of stroke rates, and a decrease in gastrointestinal bleeding rates compared to the control device.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: M.R. Mehra Tags: (4) Source Type: research
Percent Increase in Left Ventricular Stroke Work Index and Right Ventricular Stroke Work Index after Milrinone Infusion Predicts Escalation of Therapy and Mortality
We hypothesized that changes in biventricular function would approximate myocardial reserve and predict outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: U.A. Siddiqi, M. Belkin, S. Kalantari, A. Kanelidis, T. Miller, N. Sarswat, A. Nguyen, B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (638) Source Type: research
Prognostic Role of Simultaneous Assessment of Biventricular Function Using Left Ventricular Stroke Work Index and Right Ventricular Stroke Work Index
We hypothesized that simultaneous assessment of biventricular function could predict clinical outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: U.A. Siddiqi, M. Belkin, S. Kalantari, A. Kanelidis, T. Miller, N. Sarswat, A. Nguyen, B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (632) Source Type: research
Neurologic Complications After Pediatric Heart Transplant: A Single-Center Experience
CONCLUSIONS: Neurologic complications may lead to serious mortality and morbidity in pediatric heart transplant patients. Seizures, posterior reversible encephalopathy syndrome, stroke, peripheral neuropathy, transient ischemic attack, and cerebral infections are the most common neurologic complications, which are seen in the perioperative period in particular. Careful follow-up of pediatric heart transplant patients, with detection and early treatment of neurologic findings, will contribute to lower rates of sequelae. To our knowledge, this is the largest study to show a detailed experience of neurologic complications in ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 2, 2021 Category: Transplant Surgery Authors: Ali Orgun Ilkay Erdogan Birg ül Varan Taner Sezer N K ürsad Tokel Murat Özkan Atilla Sezgin Source Type: research
Outcomes of systemic anticoagulation with bivalirudin for Impella 5.0
Int J Artif Organs. 2021 Jul 12:3913988211032238. doi: 10.1177/03913988211032238. Online ahead of print.ABSTRACTTemporary mechanical circulatory support (tMCS) devices are used for the management of cardiogenic shock. The Impella 5.0 (Abiomed; Danvers, MA) (IMP5) is a commonly used, surgically implanted, tMCS device that requires systemic anticoagulation and purge solution to avoid pump failure. To avoid heparin-induced thrombocytopenia (HIT) from unfractionated heparin (UFH) use, our program has explored the utility of bivalirudin (BIV) for systemic anticoagulation in IMP5. This single center, retrospective study included...
Source: The International Journal of Artificial Organs - July 12, 2021 Category: Transplant Surgery Authors: Carly Fabrizio Marissa N Levito Ryan Rivosecchi Michael Bashline Brittany Slocum Arman Kilic Catalin Toma Holt Murray Raj Ramanan Jeffrey Fowler Gavin W Hickey Edward T Horn Source Type: research
Comparison of Impella 5.0 and extracorporeal left ventricular assist device in patients with cardiogenic shock
CONCLUSION: Impella 5.0 facilitates smoother management as a bridge to decision and reduces surgical invasiveness during durable LVAD implantation.PMID:34488481 | DOI:10.1177/03913988211040530
Source: The International Journal of Artificial Organs - September 7, 2021 Category: Transplant Surgery Authors: Toru Kondo Ryota Morimoto Masato Mutsuga Kazuro Fujimoto Takahiro Okumura Naoki Shibata Shingo Kazama Yuki Kimira Hideo Oishi Tasuku Kuwayama Hiroaki Hiraiwa Akihiko Usui Toyoaki Murohara Source Type: research
Effect of Sertoli Cell Transplant and Rapamycin Pretreatment on Middle Cerebral Artery Occlusion-Induced Brain Ischemia in a Rat Model
CONCLUSIONS: Pretreatment with Sertoli cell transplant plus rapamycin injection may enhance neural survival during ischemia through increased glial cell-derived neurotrophic factor and vascular endothelial growth factor, inhibiting the mechanistic target of rapamycin pathway and increasing autophagy performance.PMID:34812711 | DOI:10.6002/ect.2021.0198
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 23, 2021 Category: Transplant Surgery Authors: Sara Moradpour Abbas Aliaghaei Mohammadreza Bigdeli Source Type: research
