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Total 601 results found since Jan 2013.

Sensors, Vol. 23, Pages 2656: Laboratory-Based Examination of the Reliability and Validity of Kinematic Measures of Wrist and Finger Function Collected by a Telerehabilitation System in Persons with Chronic Stroke
Gerard Fluet We have developed the New Jersey Institute of Technology—Home Virtual Rehabilitation System (NJIT—HoVRS) to facilitate intensive, hand-focused rehabilitation in the home. We developed testing simulations with the goal of providing richer information for clinicians performing remote assessments. This paper presents the results of reliability testing examining differences between in-person and remote testing as well as discriminatory and convergent validity testing of a battery of six kinematic measures collected with NJIT—HoVRS. Two different groups of persons wi...
Source: Sensors - February 28, 2023 Category: Biotechnology Authors: Ashley MontJohnson Amanda Cronce Qinyin Qiu Jigna Patel Mee Eriksson Alma Merians Sergei Adamovich Gerard Fluet Tags: Article Source Type: research

Sensors, Vol. 23, Pages 2592: Modeling of Rapid Pam Systems Based on Electrothermal Micromirror for High-Resolution Facial Angiography
huqing Wang In this paper, a portable photoacoustic microscopy (PAM) system is proposed based on a large stroke electrothermal micromirror to achieve high resolution and fast imaging. The crucial micromirror in the system realizes a precise and efficient 2-axis control. Two different designs of electrothermal actuators with “O” and “Z” shape are evenly located around the four directions of mirror plate. With a symmetrical structure, the actuator realized single direction drive only. The finite element modelling of both two proposed micromirror has realized a large...
Source: Sensors - February 26, 2023 Category: Biotechnology Authors: Yuanlin Xia Yujie Wang Tianxiang Liang Zhen Peng Liang He Zhuqing Wang Tags: Article Source Type: research

Sensors, Vol. 23, Pages 2573: Design Principle and Proofing of a New Smart Textile Material That Acts as a Sensor for Immobility in Severe Bed-Confined Patients
We describe the textile composition and circuit design as well as the preliminary data collected during testing to demonstrate the validity of the complete solution. These results suggest that the smart textile sheet is a very sensitive pressure sensor and can provide continuous discriminatory information to allow for the very sensitive, real-time detection of immobility.
Source: Sensors - February 25, 2023 Category: Biotechnology Authors: Bogdan Florin Iliescu Vlad Niki Mancasi Ionut Dumitru Ilie Iulian Mancasi Bogdan Costachescu Daniel Ilie Rotariu Tags: Article Source Type: research

Sensors, Vol. 23, Pages 2526: Repeatability and Temporal Consistency of Lower Limb Biomechanical Variables Expressing Interlimb Coordination during the Double-Support Phase in People with and without Stroke Sequelae
eia S. P. Sousa Reliable biomechanical methods to assess interlimb coordination during the double-support phase in post-stroke subjects are needed for assessing movement dysfunction and related variability. The data obtained could provide a significant contribution for designing rehabilitation programs and for their monitorisation. The present study aimed to determine the minimum number of gait cycles needed to obtain adequate values of repeatability and temporal consistency of lower limb kinematic, kinetic, and electromyographic parameters during the double support of walking in people with and without stroke sequelae...
Source: Sensors - February 24, 2023 Category: Biotechnology Authors: Ana G. B. Couto M ário A. P. Vaz Liliana Pinho Jos é Félix Juliana Moreira Francisco Pinho In ês Albuquerque Mesquita Ant ónio Mesquita Montes Carlos Crasto Andreia S. P. Sousa Tags: Article Source Type: research

Two-step method fabricating a 3D nerve cell model with brain-like mechanical properties and tunable porosity vascular structures via coaxial printing
Colloids Surf B Biointerfaces. 2023 Feb 12;224:113202. doi: 10.1016/j.colsurfb.2023.113202. Online ahead of print.ABSTRACTThree-dimensional (3D) nerve cell models have been widely developed to understand the mechanisms and discover treatment methods of ischemic stroke and neurodegenerative disease. However, there is a contradiction in the production of 3D models that they should possess high modulus to ensure mechanical stability while low modulus to provide mechanical stimuli for nerve cells. In addition, it is challenging to maintain the long-term viability of 3D models when lacking vascular structures. Here, a 3D nerve ...
Source: Colloids and Surfaces - February 21, 2023 Category: Biotechnology Authors: Zhichao Wang Chuanzhen Huang Hanlian Liu Zhenyu Shi Xu Han Shuying Li Jun Huang Zhen Wang Yonggan Yan Zhuang Chen Source Type: research

Sensors, Vol. 23, Pages 2232: Video-based Goniometer Applications for Measuring Knee Joint Angles during Walking in Neurological Patients: A Validity, Reliability and Usability Study
This study discussed goniometer applications (DrGoniometer and Angles - Video Goniometer) that measure knee joint ROM during walking through smartphone cameras. The primary aim of the study is to test the inter-rater and intra-rater reliability of the collected measurements as well as their concurrent validity with an electro-goniometer. The secondary aim is to evaluate the usability of the two mobile applications. A total of 22 patients with Parkinson’s disease (18 males, age 72 (8) years), 22 post-stroke patients (17 males, age 61 (13) years), and as many healthy volunteers (8 males, age 45 (5) years) under...
Source: Sensors - February 16, 2023 Category: Biotechnology Authors: Monica Parati Matteo Gallotta Beatrice De Maria Annalisa Pirola Matteo Morini Luca Longoni Emilia Ambrosini Giorgio Ferriero Simona Ferrante Tags: Article Source Type: research

Sensors, Vol. 23, Pages 2031: On the Role of Training Data for SVM-Based Microwave Brain Stroke Detection and Classification
o Marco Salucci The aim of this work was to test microwave brain stroke detection and classification using support vector machines (SVMs). We tested how the nature and variability of training data and system parameters impact the achieved classification accuracy. Using experimentally verified numerical models, a large database of synthetic training and test data was created. The models consist of an antenna array surrounding reconfigurable geometrically and dielectrically realistic human head phantoms with virtually inserted strokes of arbitrary size, and different dielectric parameters in different positions. The ge...
Source: Sensors - February 10, 2023 Category: Biotechnology Authors: Tomas Pokorny Jan Vrba Ondrej Fiser David Vrba Tomas Drizdal Marek Novak Luca Tosi Alessandro Polo Marco Salucci Tags: Article Source Type: research

Sensors, Vol. 23, Pages 1900: Multi Modal Feature Extraction for Classification of Vascular Dementia in Post-Stroke Patients Based on EEG Signal
This study used 19 EEG channels recorded from normal elderly, post-stroke with mild cognitive impairment, and post-stroke with dementia. The QEEG method used for feature extraction includes relative power, coherence, and signal complexity; the evaluation performance of normal-mild cognitive impairment-dementia classification was conducted using Support Vector Machine and K-Nearest Neighbor. The results of the classification simulation showed the highest accuracy of 96% by Gaussian SVM with a sensitivity and specificity of 95.6% and 97.9%, respectively. This study is expected to be an additional criterion in the diagnosis o...
Source: Sensors - February 8, 2023 Category: Biotechnology Authors: Sugondo Hadiyoso Hasballah Zakaria Paulus Anam Ong Tati Latifah Erawati Rajab Tags: Article Source Type: research

Manufacture of extracellular vesicles derived from mesenchymal stromal cells
Trends Biotechnol. 2023 Feb 6:S0167-7799(23)00020-3. doi: 10.1016/j.tibtech.2023.01.003. Online ahead of print.ABSTRACTMesenchymal stromal cells (MSCs) are a promising therapy for various diseases ranging from ischemic stroke to wound healing and cancer. Their therapeutic effects are mainly mediated by secretome-derived paracrine factors, with extracellular vesicles (EVs) proven to play a key role. This has led to promising research on the potential of MSC-EVs as regenerative, off-the-shelf therapeutic agents. However, the translation of MSC-EVs into the clinic is hampered by the poor scalability of their production. Recen...
Source: Trends in Biotechnology - February 7, 2023 Category: Biotechnology Authors: Paula M Pincela Lins Elke Pirlet Michal Szymonik Annelies Bronckaers Inge Nelissen Source Type: research

Sensors, Vol. 23, Pages 1712: Immersive Virtual Reality in Post-Stroke Rehabilitation: A Systematic Review
This study aims to investigate the efficacy of FIVR in stroke rehabilitation. PubMed, Web of Science and Scopus were screened up to November 2022 to identify eligible randomized controlled trials (RCTs). Out of 4623, we included 12 RCTs involving post-acute and chronic stroke survivors, with a total of 350 patients (234 men and 115 women; mean age 58.36 years). High heterogeneity of the outcomes considered, the results showed that FIVR provides additional benefits, in comparison with standard rehabilitation. In particular, results showed an improvement in upper limb dexterity, gait performance and dynamic balance, influenc...
Source: Sensors - February 3, 2023 Category: Biotechnology Authors: Andrea Demeco Laura Zola Antonio Frizziero Chiara Martini Arrigo Palumbo Ruben Foresti Giovanni Buccino Cosimo Costantino Tags: Review Source Type: research

Sensors, Vol. 23, Pages 1289: Time-Based and Path-Based Analysis of Upper-Limb Movements during Activities of Daily Living
Mihelj Patients after stroke need to re-learn functional movements required for independent living throughout the rehabilitation process. In the study, we used a wearable sensory system for monitoring the movement of the upper limbs while performing activities of daily living. We implemented time-based and path-based segmentation of movement trajectories and muscle activity to quantify the activities of the unaffected and the affected upper limbs. While time-based segmentation splits the trajectory in quants of equal duration, path-based segmentation isolates completed movements. We analyzed the hand movement path and ...
Source: Sensors - January 23, 2023 Category: Biotechnology Authors: Sebastjan Šlajpah Eva Čebašek Marko Munih Matja ž Mihelj Tags: Article Source Type: research