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Dihydromyricetin ameliorates oxygen ‑glucose deprivation and re‑oxygenation‑induced injury in HT22 cells by activating the Wnt/β‑catenin signaling pathway
In conclusion, DMY protected HT22 cells from OGD/R‑induced oxidative stress and apoptosis, and its effects may be mediated by the activation of the Wnt/β‑catenin signaling pathway.PMID:35088876 | DOI:10.3892/mmr.2022.12619
Source: Molecular Medicine Reports - January 28, 2022 Category: Molecular Biology Authors: Xiaoxiao Tao Yaping Jiang Xian Zheng Xiaoxiao Ji Feifei Peng Source Type: research

Carthamin yellow improves cerebral ischemia ‑reperfusion injury by attenuating inflammation and ferroptosis in rats.
Carthamin yellow improves cerebral ischemia‑reperfusion injury by attenuating inflammation and ferroptosis in rats. Int J Mol Med. 2021 Apr;47(4): Authors: Guo H, Zhu L, Tang P, Chen D, Li Y, Li J, Bao C Abstract Carthamin yellow (CY), a flavonoid compound extracted from safflower, has been reported to attenuate cardiac ischemia and reperfusion injury. However, whether CY could ameliorate ischemic stroke is not completely understood. In the present study, the preventive effects of CY on experimental ischemic stroke were investigated using middle cerebral artery occlusion (MCAO) model rats. Neurologi...
Source: International Journal of Molecular Medicine - February 13, 2021 Category: Molecular Biology Authors: Guo H, Zhu L, Tang P, Chen D, Li Y, Li J, Bao C Tags: Int J Mol Med Source Type: research

Xanthohumol protects neuron from cerebral ischemia injury in experimental stroke.
In conclusion, the neuroprotective effects of XN showed in this study make XN a promising supplement for ischemic stroke protection. PMID: 32108303 [PubMed - as supplied by publisher]
Source: Molecular Biology Reports - February 26, 2020 Category: Molecular Biology Authors: Jiao Y, Cao Y, Lu X, Wang J, Saitgareeva A, Kong X, Song C, Li J, Tian K, Zhang S, Bai M, Li S, Zhang H, Wang L Tags: Mol Biol Rep Source Type: research