• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

The effects of omega-3 fatty acids in type 2 diabetes: A systematic review and meta-analysis
The number of patients with type 2 diabetes continues to increase worldwide, the disease currently affects more than 463 million people worldwide and accounts for 10% of health care spending according to data by the World Health Organization[1]. Type 2 diabetes is a multifactorial disease that is caused by pancreatic beta-cell dysfunction and insulin resistance in peripheral tissues[2], and both morbidity and mortality are high particularly due to its associated macrovascular diseases complications (Coronary artery disease (CAD), peripheral artery disease (PAD) and stroke), as well as microvascular disease complications (d...
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - June 3, 2022 Category: Biomedical Science Authors: Yanan Xiao, Qifang Zhang, Xueling Liao, Ulf Elbelt, Karsten H. Weylandt Tags: Original research article Source Type: research

Survey of the Erythrocyte EPA+DHA Levels in the Heart Attack/Stroke Belt
There is a clear geographical disparity in risk for cardiovascular disease (CVD) in the US, with a “heart attack/stroke belt” (hereafter the CVD belt) located primarily in the south east/central region (Figure 1). Low omega-3 fatty acid levels in the blood are known to be a risk factor for CVD independent of traditional lipid and inflammatory biomarkers, blood pressure, diabetes and smoking s tatus [1-6]. The extent to which a relatively low omega-3 levels contributes to this increased risk in this region is unknown.
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - July 12, 2019 Category: Biomedical Science Authors: W.S. Harris, K.H. Jackson, J.T. Brenna, J.C. Rodriguez, N.L. Tintle, L. Cornish Source Type: research

Natural approaches in metabolic syndrome management.
Authors: Patti AM, Al-Rasadi K, Giglio RV, Nikolic D, Mannina C, Castellino G, Chianetta R, Banach M, Cicero AFG, Lippi G, Montalto G, Rizzo M, Toth PP Abstract Metabolic syndrome (MetS) is characterized as a group of cardiometabolic risk factors that raise the risk for heart disease and other health problems, such as diabetes mellitus and stroke. Treatment strategies include pharmacologic interventions and supplementary (or "alternative") treatments. Nutraceuticals are derived from food sources (isolated nutrients, dietary supplements and herbal products) that are purported to provide health benefits, in addition ...
Source: Archives of Medical Science - March 30, 2018 Category: Biomedical Science Tags: Arch Med Sci Source Type: research

The Omega-6:Omega-3 Ratio: A Critical Appraisal and Possible Successor
There is a growing interest in exploring the relationships between fatty acid (FA) status and clinically important health outcomes [1]. These include cardiac disease [2 –4], stroke [5], diabetes [6], cognitive function [7], and aging [8–10]. However, analysis of FAs is much more complicated than it is for other biomarkers like cholesterol or glucose. The latter analytes circulate in plasma as single molecular species whose concentrations can be easily measured by long-ago standardized enzymatic methods, and optimal levels are clearly defined after decades of research, either as a risk factor for a disease [e.g., corona...
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - March 19, 2018 Category: Biomedical Science Authors: William S. Harris Source Type: research

The Omega-6:Omega-3 ratio: A critical appraisal and possible successor
There is a growing interest in exploring the relationships between fatty acid (FA) status and clinically important health outcomes [1]. These include cardiac disease [2 –4], stroke [5], diabetes [6], cognitive function [7], and aging [8–10]. However, analysis of FAs is much more complicated than it is for other biomarkers like cholesterol or glucose. The latter analytes circulate in plasma as single molecular species whose concentrations can be easily measured by long-ago standardized enzymatic methods, and optimal levels are clearly defined after decades of research, either as a risk factor for a disease [e.g., corona...
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - March 19, 2018 Category: Biomedical Science Authors: William S. Harris Source Type: research

Intravenous Treatment with a Long-Chain Omega-3 Lipid Emulsion Provides Neuroprotection in a Murine Model of Ischemic Stroke – A Pilot Study
by Dirk Berressem, Konrad Koch, Nicole Franke, Jochen Klein, Gunter P. Eckert Single long-chain omega-3 fatty acids (e.g. docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA)) are known for their neuroprotective properties associated with ischemic stroke. This pilot study aimed to test the effectiveness of an acute treatment with a long-chain omega-3 lipid emulsion (Om egaven 10%®, OGV) that contains fish oil (DHA 18 mg/ml; EPA 21 mg/ml) and α-tocopherol (0.2 mg/ml) in a transient middle cerebral artery occlusion (MCAO) model of ischemic stroke in mice. For this purpose, female CD-1 mice were anesthetized and subje...
Source: PLoS One - November 29, 2016 Category: Biomedical Science Authors: Dirk Berressem Source Type: research