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Total 33 results found since Jan 2013.
Second death linked to potential antibody treatment for Alzheimer ’s disease
A 65-year-old woman who was receiving a promising experimental treatment to slow the cognitive decline caused by her early Alzheimer’s disease recently died from a massive brain hemorrhage that some researchers link to the drug. The clinical trial death, described in an unpublished case report
Science
has obtained, is the second thought to be associated with the antibody called lecanemab. The newly disclosed fatality intensifies questions about its safety and how widely lecanemab should be prescribed if ultimately approved by regulators.
The woman, who received infusions of the antibody as part of the trial, s...
Source: ScienceNOW - November 28, 2022 Category: Science Source Type: news
Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans Neuroscience
Restoration of human brain function after injury is a signal challenge for translational neuroscience. Rodent stroke recovery studies identify an optimal or sensitive period for intensive motor training after stroke: near-full recovery is attained if task-specific motor training occurs during this sensitive window. We extended these findings to adult humans...
Source: Proceedings of the National Academy of Sciences - September 20, 2021 Category: Science Authors: Alexander W. Dromerick, Shashwati Geed, Jessica Barth, Kathaleen Brady, Margot L. Giannetti, Abigail Mitchell, Matthew A. Edwardson, Ming T. Tan, Yizhao Zhou, Elissa L. Newport, Dorothy F. Edwards Tags: Neuroscience Biological Sciences Source Type: research
CRMP2-binding compound, edonerpic maleate, accelerates motor function recovery from brain damage
Brain damage such as stroke is a devastating neurological condition that may severely compromise patient quality of life. No effective medication-mediated intervention to accelerate rehabilitation has been established. We found that a small compound, edonerpic maleate, facilitated experience-driven synaptic glutamate AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic-acid) receptor delivery and resulted in the acceleration of motor function recovery after motor cortex cryoinjury in mice in a training-dependent manner through cortical reorganization. Edonerpic bound to collapsin-response-mediator-protein 2 (CRMP2)...
Source: ScienceNOW - April 5, 2018 Category: Science Authors: Abe, H., Jitsuki, S., Nakajima, W., Murata, Y., Jitsuki-Takahashi, A., Katsuno, Y., Tada, H., Sano, A., Suyama, K., Mochizuki, N., Komori, T., Masuyama, H., Okuda, T., Goshima, Y., Higo, N., Takahashi, T. Tags: Medicine, Diseases, Neuroscience r-articles Source Type: news
Exercise May Be As Valuable As Good Genes In Lowering Dementia Risk
This study is still epidemiological data, Heisz noted ― which means it shows a link between sedentary behavior and dementia risk, but doesn’t necessarily explain how one leads to the other.
But taken with previous research that has linked physical activity is to lower dementia risk, the results are fairly convincing, she added. This study included a large number of individuals, it followed those individuals for five years and it controlled for other dementia risk factors, including age, heart disease, stroke, diabetes, high blood pressure, depression and smoking.
More studies are needed to identify what types...
Source: Science - The Huffington Post - January 31, 2017 Category: Science Source Type: news
How family tragedy turned Roald Dahl into a medical pioneer
After his wife ’s stroke and his daughter’s death from measles, Roald Dahl applied his genius to medicine – making extraordinary breakthroughs. His doctor and friend recalls what he learned while treating the author in the last year of his lifeIn 1990, I was a junior doctor at the John Radcliffe hospital in Oxford. I had finished all my training, and was now starting my first year on the wards.Roald Dahl was one of my patients. I can still remember the night I first met him.It was nearly midnight and the lights were low. I was working away on the ward computer when I became aware of this large figure wandering slowly...
Source: Guardian Unlimited Science - September 12, 2016 Category: Science Authors: Tom Solomon Tags: Roald Dahl Books Culture Fiction Medical research Health Source Type: news
Hillary Clinton's New Platform Is A Blow To Mental Health Stigma
Democratic presidential nominee Hillary Clinton released a wide-ranging mental health plan on Monday, saying that her office would support Americans living with mental health issues through better legislation.
“The next generation must grow up knowing that mental health is a key component of overall health and there is no shame, stigma or barriers to seeking out care,” Clinton’s campaign stressed in an announcement.
Of course, candidate platforms rarely remain intact if they actually become policy after election day, but Clinton’s focus on normalizing mental health treatment reflects growi...
Source: Science - The Huffington Post - August 30, 2016 Category: Science Source Type: news
The Real-Life Ghostbusters of the Brain
This article was originally posted on Inverse.
By Yasmin Tayag
"In a sense, we are absolutely the ghosts we are sensing," Giulio Rognini, Ph.D., a senior scientist at EPFL's Laboratory of Cognitive Neuroscience, says.
Rognini is part of a team of researchers at Switzerland's Ecole Polytechnique Fédérale de Lausanne that might be best described as the real-life ghostbusters. The team is attempting to understand what makes our brains want to believe that apparitions are ghosts.
While he's more than willing to admit that ghostly sensations are completely real, he'll be the first to point out that they're not actually ca...
Source: Science - The Huffington Post - July 19, 2016 Category: Science Source Type: news
Ritalin Could Trigger Heart Problems In Children
Ritalin and similar forms of ADHD medication may trigger abnormal heart rhythms and increase heart attack risk in some children soon after they start taking the drug, according to a new study.
This connection was especially true for children who were born with heart disease.
According to the study, published in the British medical journal BMJ, kids had an increased risk of heart attack between eight and 56 days after starting methylphenidate, a stimulant most commonly sold as Ritalin, although this heightened risk didn’t reach statistical significance. The researchers could find no evidence of a heightened...
Source: Science - The Huffington Post - June 8, 2016 Category: Science Source Type: news
If you can't imagine things, how can you learn?
We know some people can’t conjure up mental images. But we’re only beginning to understand the impact this “aphantasia” might have on their educationNever underestimate the power of visualisation. It may sound like a self-help mantra, but a growing body of evidence shows that mental imagery can accelerate learning and improve performance of all sorts of skills. For athletes and musicians, “going through the motions,” or mentally rehearsing the movements in the mind, is just as effective as physical training, and motor imagery can also help stroke patients regain function of their paralysed limbs.For most of us,...
Source: Guardian Unlimited Science - June 4, 2016 Category: Science Authors: Mo Costandi Tags: Students Education Higher education Neuroscience Psychology Source Type: news
Does the Brain Filter out a Wider Awareness?
The human brain has amazing capacities. It contains billions of neurons, allowing it to process vast quantities of information so that we can function effectively. But can we have too much information? Yes, and, in fact, filtering information is one of the brain's most important functions. Brain filtering is an adaptive strategy and ensures that only the information relevant to our goals is allowed into our consciousness. This keeps us from being flooded with irrelevancies that might distract us.
To introduce brain filtering to my neuroscience students, I show them a video of two teams throwing a ball back and forth, and ...
Source: Science - The Huffington Post - May 9, 2016 Category: Science Source Type: news
White Doctors In Training Believe Some Disturbing Stuff About Black Patients
When it comes to emergency care, you may have a tough time if you're in pain and not a white man. Previous research has shown that black and Hispanic patients who reported severe pain in the the ER were 22 percent less likely to receive pain medication than white patients who presented with the same complaints. And women suffer similar disparities: A 2008 study found that women wait an average of 16 minutes longer to receive pain relief for acute abdominal pain in the ER than men do. Now a new study is shedding some light on this phenomenon. "We’ve been looking at racial bias and pain perception to tr...
Source: Science - The Huffington Post - April 8, 2016 Category: Science Source Type: news
Electrical brain stimulation could support stroke recovery
Medical researchers have studied the use of transcranial direct current stimulation to support rehabilitation training for stroke patients and found that those who had tCDS had better outcomes.
Source: ScienceDaily Headlines - March 16, 2016 Category: Science Source Type: news
Here's How Meditation Reduces Inflammation And Prevents Disease
Science has shown that mindfulness meditation can have a positive impact on a huge range of health conditions, including cancer, depression and post-traumatic stress disorder. The practice has even been found to slow HIV progression and protect the brain from aging.
Mindfulness seems to improve nearly every aspect of health -- but how? While mounting research has revealed many of the numerous physical and mental health benefits of mindfulness, little is known of the mechanisms underlying these positive changes.
Now, a new study from Carnegie Mellon University, published on Jan. 29 i...
Source: Science - The Huffington Post - February 8, 2016 Category: Science Source Type: news
This Is By Far The Best Way To Avoid Lower Back Pain
By: Cari Nierenberg Published: 01/11/2016 06:35 PM EST on LiveScience Shoe inserts, back-support belts and other gadgets aimed at preventing low back pain may be a waste of money. Instead, exercise is the best way to ward off this common problem, a new review of studies suggests. The researchers found evidence that an exercise program alone, or exercise along with education about how to prevent back pain, was effective in averting an episode of low back pain and reducing people's use of sick time at work. Education may include receiving training in proper lifting techniques, learning about correct posture or attending...
Source: Science - The Huffington Post - January 12, 2016 Category: Science Source Type: news
In The Marshall Islands, Traditional Agriculture And Healthy Eating Are A Climate Change Strategy
LAURA VILLAGE, Marshall Islands -- Holding in his hand a bunch of what he called mountain apples, Steve Lepton grinned like a kid with a new toy. “Oh, it’s good,” he said. “Yesterday I didn’t find any fruit on this one. Wow, this is great. They’re getting red.” The delicate little fruit is crunchy like an apple and sweet. It’s a popular snack in the Marshall Islands, Lepton told The WorldPost, but kids pickle it with salt and Kool-Aid, which defeats the purpose of eating fruit in the first place. As the Global Climate and Health Alliance made clear with an announcement ...
Source: Science - The Huffington Post - December 12, 2015 Category: Science Source Type: news
