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Fertility preservation in women with sickle cell disease prior to curative therapy with stem cell transplant: a case series
Sickle cell disease (SCD) is an inherited hemoglobinopathy affecting approximately 100,000 Americans (1). Due to the pathognomonic sickling of red blood cells, individuals with SCD are at risk of venous thromboembolism, hemolytic anemia, stroke, pain crises, infection and end organ damage (2). Hematopoietic stem cell transplant (HSCT), while curative, can also lead to gonadal dysfunction and thereby ovarian insufficiency due to the associated myeloablative and radiative conditioning regimens (3).
Source: Fertility and Sterility - July 1, 2023 Category: Reproduction Medicine Authors: M. Yamasaki, P. Lindner, A. Decherney, T. Spitzer Source Type: research

Surgical results in POP/UI surgery after using PVDF compared to other materials. A systematic review and meta-analysis
CONCLUSIONS: This study provided evidence that the use of PVDF in SUI/POP surgeries could be a valid alternative to PP. However our results are limited by uncertainty due to the overall low quality of the existent data. Further research and validation would contribute to better surgical techniques.PMID:36966589 | DOI:10.1016/j.ejogrb.2023.03.018
Source: Reproductive Biology - March 26, 2023 Category: Reproduction Medicine Authors: Tilemachos Karalis Sofia Tsiapakidou Grigoris F Grimbizis Themistoklis Mikos Source Type: research

Effect of desogestrel 75 µg on headache frequency and intensity in women with migraine: a prospective controlled trial.
CONCLUSION: These data demonstrate for the first time in a prospective controlled setting that daily use of the progestin desogestrel is associated with a decrease in migraine frequency, migraine intensity and pain medication use in women with migraine, with and without aura, who had previously been experiencing at least three days of migraine per month. TRIAL REGISTRATION: The study is registered in the University of Zürich database ( www.research-projects.uzh.ch/unizh.htm ). PMID: 31094588 [PubMed - as supplied by publisher]
Source: The European Journal of Contraception and Reproductive Health Care - May 15, 2019 Category: Reproduction Medicine Authors: Merki-Feld GS, Imthurn B, Gantenbein AR, Sandor P Tags: Eur J Contracept Reprod Health Care Source Type: research