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Specialty: Reproduction Medicine

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Total 61 results found since Jan 2013.

Fertility preservation in women with sickle cell disease prior to curative therapy with stem cell transplant: a case series
Sickle cell disease (SCD) is an inherited hemoglobinopathy affecting approximately 100,000 Americans (1). Due to the pathognomonic sickling of red blood cells, individuals with SCD are at risk of venous thromboembolism, hemolytic anemia, stroke, pain crises, infection and end organ damage (2). Hematopoietic stem cell transplant (HSCT), while curative, can also lead to gonadal dysfunction and thereby ovarian insufficiency due to the associated myeloablative and radiative conditioning regimens (3).
Source: Fertility and Sterility - July 1, 2023 Category: Reproduction Medicine Authors: M. Yamasaki, P. Lindner, A. Decherney, T. Spitzer Source Type: research

Is early age at menarche associated with multimorbidity? Findings from the Azar Cohort study
CONCLUSION: Changes in AAM have significant health implications. Factors predisposing individuals to early menarche and its consequences should be considered in chronic disease prevention strategies for adolescents and young adults.PMID:37290234 | DOI:10.1016/j.ejogrb.2023.05.029
Source: Reproductive Biology - June 8, 2023 Category: Reproduction Medicine Authors: Amin SadrAzar Sarvin Sanaie Helda Tutunchi Bahare Sheikh Elnaz Faramarzi Neda Jourabchi-Ghadim Source Type: research

Surgical results in POP/UI surgery after using PVDF compared to other materials. A systematic review and meta-analysis
CONCLUSIONS: This study provided evidence that the use of PVDF in SUI/POP surgeries could be a valid alternative to PP. However our results are limited by uncertainty due to the overall low quality of the existent data. Further research and validation would contribute to better surgical techniques.PMID:36966589 | DOI:10.1016/j.ejogrb.2023.03.018
Source: Reproductive Biology - March 26, 2023 Category: Reproduction Medicine Authors: Tilemachos Karalis Sofia Tsiapakidou Grigoris F Grimbizis Themistoklis Mikos Source Type: research

Polycystic ovary syndrome: a “risk-enhancing” factor for cardiovascular disease
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and is hallmarked by hyperandrogenism, oligo-ovulation, and polycystic ovarian morphology. Polycystic ovary syndrome, particularly the hyperandrogenism phenotype, is associated with several cardiometabolic abnormalities, including obesity, dyslipidemia, elevated blood pressure, and prediabetes or type 2 diabetes. Many, but not all, studies have suggested that PCOS is associated with increased risk of cardiovascular disease (CVD), including coronary heart disease and stroke, independent of body mass index and traditional risk factors.
Source: Fertility and Sterility - May 1, 2022 Category: Reproduction Medicine Authors: Carolyn Guan, Salman Zahid, Anum S. Minhas, Pamela Ouyang, Arthur Vaught, Valerie L. Baker, Erin D. Michos Tags: Views and reviews Source Type: research

Reproductive complications after stroke: long-lasting impairment of GnRH neuronal network?
Biol Reprod. 2022 Apr 26:ioac080. doi: 10.1093/biolre/ioac080. Online ahead of print.ABSTRACTSome studies have demonstrated that stroke may increase the risk of pregnancy complications and early menopause. In addition, preclinical investigations revealed the middle cerebral artery occlusion could affect hypothalamus. Since hypothalamus is the core of central circuits regulating reproductive processes, impairment of hypothalamic GnRH neuronal network following stroke might be manifested in long-lasting reproductive disorders.PMID:35470856 | DOI:10.1093/biolre/ioac080
Source: Biology of Reproduction - April 26, 2022 Category: Reproduction Medicine Authors: Mohammad Saied Salehi Sareh Pandamooz Amin Tamadon Mohammad Reza Jafarzadeh Shirazi Afshin Borhani-Haghighi Source Type: research

Clinical impact of hormone replacement therapy on lone atrial fibrillation in postmenopausal women: a nationwide cohort study
Individuals with atrial fibrillation (AF), especially women, have an increased risk of stroke and death. Hormone replacement therapy (HRT) is widely used to control symptoms of menopause and treat osteoporosis in postmenopausal women. However, the association between HRT use and AF risk has been scarcely explored. Thus, we aimed to investigate the association between various types of HRT and lone AF in a national cohort of Korean menopausal women.
Source: Fertility and Sterility - September 1, 2021 Category: Reproduction Medicine Authors: Jae Hoon Lee, Sung Pil Choo, Yunjeong Park, Heeyon Kim, Young Sik Choi, SiHyun Cho, Byung Seok Lee Source Type: research

Laparoscopically-confirmed endometriosis and risk of incident stroke: a prospective cohort study
Prior research has suggested that women with endometriosis are at greater risk of cardiovascular disease later in life, including myocardial infarction and hypertension. However, there has been limited research on endometriosis and risk of stroke, which may have similar underlying pathophysiologic mechanisms. Therefore, our objective was to prospectively investigate the association between laparoscopically-confirmed endometriosis and risk of incident stroke during 28 years of follow-up.
Source: Fertility and Sterility - September 1, 2021 Category: Reproduction Medicine Authors: Leslie V. Farland, William J. Degnan, Melanie Bell, Kathryn M. Rexrode, Stacey A. Missmer Source Type: research

P –358 Characteristics of patients with inherited thrombophilia and anticoagulant treatment in repeated implantation failure (RIF) and recurrent pregnancy loss (RPL)
AbstractStudy questionDo patients with inherited thrombophilia associated to RIF and RPL benefit from anticoagulant therapy?Summary answerLow molecular weight heparin (LMWH) in patients with medium and high risk of hereditary thrombophilia, associated with RIF could improve the reproductive prognosis.What is known alreadyThrombophilia is a condition that can be acquired and/or inherited genetically, that is characterized by the predisposition of patients to form venous and arterial thromboembolic events. Inherited thrombophilia has been associated with different complications during pregnancy, such as RPL. Genetic variants...
Source: Human Reproduction - August 6, 2021 Category: Reproduction Medicine Source Type: research

Neonatal outcomes and risk of neonatal sepsis in an expectantly managed cohort of late preterm prelabor rupture of membranes
CONCLUSION: Expectant management of LpPROM should be encouraged especially between 34+0 and 34+6 weeks', when the burden of prematurity is the greatest. Antibiotics may have beneficial effects, while careful consideration should be given to antenatal corticosteroids until future studies specifically address LpPROM.PMID:33857797 | DOI:10.1016/j.ejogrb.2021.03.036
Source: Reproductive Biology - April 15, 2021 Category: Reproduction Medicine Authors: Giuseppe Chiossi Mariarosaria Di Tommaso Francesca Monari Sara Consonni Noemi Strambi Sofia Gambigliani Zoccoli Viola Seravalli Chiara Comerio Marta Betti Anna Cappello Patrizia Vergani Fabio Facchinetti Anna Locatelli Source Type: research

Stroke Treatment Gap Narrows Between Men and Women
Source: Fertility News - Doctors Lounge - June 10, 2020 Category: Reproduction Medicine Tags: Cardiology, Gynecology, Neurology, Reproductive Medicine, News, Source Type: news

Association between depression risk and polycystic ovarian syndrome in young women: a retrospective nationwide population-based cohort study (1998 –2013)
This study was supported in part by the Taiwan Ministry of Health and Welfare Clinical Trial Center (MOHW108-TDU-B-212-133  004), China Medical University Hospital, Academia Sinica Stroke Biosignature Project (BM10701010021), MOST Clinical Trial Consortium for Stroke (MOST 107-2321-B-039 -004-), Tseng-Lien Lin Foundation, Taichung, Taiwan and Katsuzo and Kiyo Aoshima Memorial Funds, Japan. No competing interest existe d.TRIAL REGISTRATION NUMBERN/A.
Source: Human Reproduction - August 13, 2019 Category: Reproduction Medicine Source Type: research

Preeclampsia may influence offspring neuroanatomy and cognitive function: A role for placental growth factor?
Abstract Preeclampsia (PE) is a common pregnancy complication affecting 3-5% of women. PE is diagnosed clinically as new-onset hypertension with associated end organ damage after 20 weeks of gestation. Despite being diagnosed as a maternal syndrome, fetal experience of PE is a developmental insult with lifelong cognitive consequences. These cognitive alterations are associated with distorted neuroanatomy and cerebrovasculature, including a higher risk of stroke. The pathophysiology of a PE pregnancy is complex, with many factors potentially able to affect fetal development. Deficient pro-angiogenic factor expressi...
Source: Biology of Reproduction - June 6, 2019 Category: Reproduction Medicine Authors: Kay VR, Rätsep MT, Figueiró-Filho EA, Croy BA Tags: Biol Reprod Source Type: research