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Specialty: Internal Medicine
Source: Mayo Clinic Proceedings

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Total 82 results found since Jan 2013.

Stroke Risk Before and After Central Retinal Artery Occlusion in a US Cohort
To determine the risk of ischemic stroke, transient ischemic attack (TIA), and amaurosis fugax around the time of central retinal artery occlusion (CRAO).
Source: Mayo Clinic Proceedings - January 31, 2019 Category: Internal Medicine Authors: Kevin D. Chodnicki, Jose S. Pulido, David O. Hodge, James P. Klaas, John J. Chen Tags: Original article Source Type: research

Cardiovascular Disease in Type 2 Diabetes: A Review of Sex-Related Differences in Predisposition and Prevention
Type 2 diabetes mellitus is a major risk factor for cardiovascular disease. However, compiled data suggest that type 2 diabetes affects the risk of cardiovascular disease differentially according to sex. In recent years, large meta-analyses have confirmed that women with type 2 diabetes have a higher relative risk of incident coronary heart disease, fatal coronary heart disease, and stroke compared with their male counterparts. The reasons for these disparities are not completely elucidated. A greater burden of cardiometabolic risk in women was proposed as a partial explanation.
Source: Mayo Clinic Proceedings - January 31, 2019 Category: Internal Medicine Authors: Abdallah Al-Salameh, Philippe Chanson, Sophie Bucher, Virginie Ringa, Laurent Becquemont Tags: Review Source Type: research

Integrated Care Management of Patients With Atrial Fibrillation and Risk of Cardiovascular Events
To investigate the impact on cardiovascular events (CVEs) in a real-world population of patients with atrial fibrillation (AF) by implementing the Atrial fibrillation Better Care (ABC: A, Avoid stroke with anticoagulation; B, better symptom management; C, Cardiovascular and comorbidity risk management) pathway.
Source: Mayo Clinic Proceedings - December 11, 2018 Category: Internal Medicine Authors: Daniele Pastori, Pasquale Pignatelli, Danilo Menichelli, Francesco Violi, Gregory Y.H. Lip Tags: Original article Source Type: research

79-Year-Old Man With Shortness of Breath and Fevers
A 79-year old man with a history of myocardial infarction and coronary artery bypass grafting in 2000, biventricular systolic heart failure with an ejection fraction of 27%, hypertension, persistent atrial fibrillation for which he was taking high-dose aspirin given a previous history of hemorrhagic stroke, stage 3 chronic kidney disease, left cerebellar ischemic stroke, and implantable cardioverter-defibrillator (ICD) placement 5 years previously presented to his local medical facility with a 2-day history of breathlessness, fevers, and chills.
Source: Mayo Clinic Proceedings - November 7, 2018 Category: Internal Medicine Authors: Jaskanwal D. Sara, Megha Prasad, Suraj Kapa Tags: Residents' clinic Source Type: research

Association of Low Urinary Sodium Excretion With Increased Risk of Stroke
We examined the association of urinary sodium excretion (UNaV) as an accurate estimate of intake with risk of stroke. We studied 7330 individuals free of cardiovascular events at baseline in the Prevention of Renal and Vascular End-stage Disease (PREVEND) study, a prospective, population-based cohort of Dutch men and women.
Source: Mayo Clinic Proceedings - September 20, 2018 Category: Internal Medicine Authors: Lyanne M. Kieneker, Michele F. Eisenga, Ron T. Gansevoort, Rudolf A. de Boer, Gerjan Navis, Robin P.F. Dullaart, Michel M. Joosten, Stephan J.L. Bakker Tags: Brief report Source Type: research

Racial Differences in the Association Between Nonexercise Estimated Cardiorespiratory Fitness and Incident Stroke
To examine the association between estimated cardiorespiratory fitness (eCRF) and incident stroke by black and white race.
Source: Mayo Clinic Proceedings - June 11, 2018 Category: Internal Medicine Authors: Xuemei Sui, Virginia J. Howard, Michelle N. McDonnell, Linda Ernstsen, Matthew L. Flaherty, Steven P. Hooker, Carl J. Lavie Tags: Original article Source Type: research

Case-Based Discussion Regarding Challenges in Patient Selection and Procedural Planning in Left Atrial Appendage Occlusion
Atrial fibrillation (AF) accounts for most embolic strokes, especially in elderly individuals. Although anticoagulation is known to reduce the risk of embolic stroke, a significant proportion of patients have relative or absolute contraindications to anticoagulation. The left atrial appendage has been implicated as the major source of emboli in more than 90% of ischemic strokes in nonvalvular AF. Left atrial appendage occlusion offers an alternative for stroke prevention in patients with an elevated stroke risk (CHADS2 score ≥2 or CHA2DS2-VASc score ≥3) who have a rationale for avoiding long-term oral anticoagulation a...
Source: Mayo Clinic Proceedings - May 1, 2018 Category: Internal Medicine Authors: Sidakpal S. Panaich, Thomas Munger, Paul Friedman, Charanjit S. Rihal, David R. Holmes Tags: Review Source Type: research

Diagnosis and Management of Acute Ischemic Stroke
Acute ischemic stroke (AIS) is among the leading causes of death and long-term disability. Intravenous tissue plasminogen activator has been the mainstay of acute therapy. Recently, several prospective randomized trials documented the value of endovascular revascularization in selected patients with large-vessel occlusion within the anterior circulation. This finding has led to a paradigm shift in the management of AIS, including wide adoption of noninvasive neuroimaging to assess vessel patency and tissue viability, with the supplemental and independent use of intravenous tissue plasminogen activator to improve clinical outcomes.
Source: Mayo Clinic Proceedings - April 1, 2018 Category: Internal Medicine Authors: Tasneem F. Hasan, Alejandro A. Rabinstein, Erik H. Middlebrooks, Neil Haranhalli, Scott L. Silliman, James F. Meschia, Rabih G. Tawk Tags: Thematic reviews on neurosciences Source Type: research

Palliative Care in Neurology
Palliative medicine is a specialty that focuses on improving the quality of life for patients with serious or advanced medical conditions, and it is appropriate at any stage of disease, including at the time of diagnosis. Neurologic conditions tend to have high symptom burdens, variable disease courses, and poor prognoses that affect not only patients but also their families and caregivers. Patients with a variety of neurologic conditions such as Parkinson disease, dementia, amyotrophic lateral sclerosis, brain tumors, stroke, and acute neurologic illnesses have substantial unmet needs that can be addressed through a combi...
Source: Mayo Clinic Proceedings - October 1, 2017 Category: Internal Medicine Authors: Maisha T. Robinson, Robert G. Holloway Tags: Symposium on neurosciences Source Type: research

Guideline-Adherent Antithrombotic Treatment Improves Outcomes in Patients With Atrial Fibrillation
To assess the influence of guideline-adherent vs nonadherent antithrombotic treatment (ATT) on stroke and mortality rates in an atrial fibrillation (AF) primary care population.
Source: Mayo Clinic Proceedings - August 1, 2017 Category: Internal Medicine Authors: Micha ł Mazurek, Eduard Shantsila, Deirdre A. Lane, Andreas Wolff, Marco Proietti, Gregory Y.H. Lip Tags: Original article Source Type: research

Evaluation and Management of Atherosclerotic Carotid Stenosis
Medical therapies for the prevention of stroke have advanced considerably in the past several years. There can also be a role for mechanical restoration of the lumen by endarterectomy or stenting in selected patients with high-grade atherosclerotic stenosis of the extracranial carotid artery. Endarterectomy is generally recommended for patients with high-grade symptomatic carotid stenosis. Stenting is considered an option for patients at high risk of complications with endarterectomy. Whether revascularization is better than contemporary medical therapy for asymptomatic extracranial carotid stenosis is a subject of several...
Source: Mayo Clinic Proceedings - July 1, 2017 Category: Internal Medicine Authors: James F. Meschia, James P. Klaas, Robert D. Brown, Thomas G. Brott Tags: Symposium on neurosciences Source Type: research

CHA2DS2-VASc Score: A Predictor of Thromboembolic Events and Mortality in Patients With an Implantable Monitoring Device Without Atrial Fibrillation
To determine if the CHA2DS2-VASc score (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke or transient ischemic attack, vascular disease, age 65-74 years, sex category) predicts thromboembolism and death in patients without atrial fibrillation in a population with implantable cardiac monitoring devices.
Source: Mayo Clinic Proceedings - February 28, 2017 Category: Internal Medicine Authors: Christine Parsons, Salma I. Patel, Stephen Cha, Win-Kuang Shen, Santosh Desai, Alanna M. Chamberlain, Sushil Allen Luis, Maria I. Aguilar, Bart M. Demaerschalk, Farouk Mookadam, Fadi Shamoun Tags: Original article Source Type: research

The Pooled Cohort Equations for Predicting Risk of Myocardial Infarction and Stroke: Validated in Representative Natural History Populations
The American College of Cardiology (ACC)/American Heart Association (AHA) Pooled Cohort equations (PCEs) were introduced in late 2013 and published in mid-2014.1 Unlike the Framingham score used to determine coronary heart disease (CHD) risk in the National Cholesterol Education Program Adult Treatment Panel III guidelines,2 the new PCEs focused on estimating risk of CHD and stroke and additionally provided specific risk assessment for African American individuals. Because stroke may occur before CHD, particularly in women and African Americans, the PCEs were seen as a major advance in disease prognostication.
Source: Mayo Clinic Proceedings - May 10, 2016 Category: Internal Medicine Authors: Neil J. Stone, Donald M. Lloyd-Jones Tags: Editorial Source Type: research

Impact on Outcomes of Changing Treatment Guideline Recommendations for Stroke Prevention in Atrial Fibrillation: A Nationwide Cohort Study
To investigate the impact on outcomes of changing treatment guideline recommendations by comparing the proportion of patients with atrial fibrillation (AF) recommended oral anticoagulants (OACs) under the 2011 and 2014 American College of Cardiology/American Heart Association (ACC/AHA) guidelines.
Source: Mayo Clinic Proceedings - April 7, 2016 Category: Internal Medicine Authors: Tze-Fan Chao, Chia-Jen Liu, Ta-Chuan Tuan, Kang-Ling Wang, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Tzeng-Ji Chen, Chern-En Chiang, Ming-Hsiung Hsieh, Gregory Y.H. Lip, Shih-Ann Chen Tags: Original article Source Type: research

Achieving the Benefits of a High-Potassium, Paleolithic Diet, Without the Toxicity
The average US dietary intake of K+ is well below the current recommended nutritional requirements. This deficiency is even more striking when comparing our current intake with that of our ancestors, who consumed large amounts of dietary K+. K+ deficiency has been implicated in many diseases including cardiovascular disease, kidney stones, and osteoporosis. Importantly, dietary supplementation of K+ has favorable effects on reducing blood pressure, decreasing the risk of stroke, improving bone health, and reducing the risk of nephrolithiasis.
Source: Mayo Clinic Proceedings - March 3, 2016 Category: Internal Medicine Authors: Biff F. Palmer, Deborah J. Clegg Tags: Review Source Type: research