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Specialty: Internal Medicine
Source: Mayo Clinic Proceedings
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Total 82 results found since Jan 2013.
Impact of Stroke Volume Index and Left Ventricular Ejection Fraction on Mortality After Aortic Valve Replacement
To assess the impact of stroke volume index (SVI) and left ventricular ejection fraction (LVEF) on prognosis in patients with severe aortic stenosis, comparing those undergoing transcatheter aortic valve replacement (TAVR) and those with surgical AVR (SAVR).
Source: Mayo Clinic Proceedings - December 31, 2019 Category: Internal Medicine Authors: Saki Ito, Vuyisile T. Nkomo, David A. Orsinelli, Grace Lin, Joao Cavalcante, Jeffrey J. Popma, David H. Adams, Stanley J. Checuti, G. Michael Deeb, Michael Boulware, Jian Huang, Stephen H. Little, Sidney A. Cohen, Michael J. Reardon, Jae K. Oh Tags: Original article Source Type: research
82-Year-Old Woman With Acute-Onset Left-Sided Weakness
An 82-year-old woman with a history of type 2 diabetes mellitus, hyperlipidemia, and hypertension presented to the emergency department with sudden onset of left arm and leg weakness. She was sitting in church when she developed left-sided posterior neck and shoulder pain, followed 1 hour later by sudden-onset dense left-sided weakness. Emergency medical services were called, and they activated the prehospital stroke-notification protocol. The patient arrived at the emergency department approximately 30 minutes after the onset of the weakness.
Source: Mayo Clinic Proceedings - December 31, 2019 Category: Internal Medicine Authors: Ronstan Lobo, Adam P. Sawatsky Tags: Residents ’ clinic Source Type: research
Vascular Event Risk After Herpes Zoster
We have read the article by Patterson et al1 published in the April 2019 issue of Mayo Clinic Proceedings. The authors performed an interesting study using propensity score to evaluate the cardiovascular disease risk during the prodromal period and aggregate period of herpes zoster (HZ) infection. The incidence rate calculated according to the time line before and after the index date also provided valuable information on the following cardiovascular risk. Evidence from large population-based studies suggests a transiently increased risk of stroke after HZ.
Source: Mayo Clinic Proceedings - July 31, 2019 Category: Internal Medicine Authors: Yi-Ting Lin, Ping-Hsun Wu Tags: Letter to the Editor Source Type: research
Strategies of Screening for Fabry Disease in Patients with Unexplained Left Ventricular Hypertrophy
In a recent article, Newman et al1 presented the results of screening for Fabry disease in 1192 adult patients with suspected hypertrophic cardiomyopathy and compared the cost efficacy of α-galactosidase A (α-gal A) measurement with comprehensive galactosidase alpha gene (GLA) testing. The established prevalence of Fabry dise ase was 0.42% and comparable to that in the previous studies. Routine α-gal A measurement followed by confirmatory GLA testing is a well-accepted strategy of screening for Fabry disease in groups that are at risk, which include patients with unexplained left ventricular hypertrophy, end-stage ren...
Source: Mayo Clinic Proceedings - July 31, 2019 Category: Internal Medicine Authors: Sergey Moiseev, Ekaterina Karovaikina, Alexey Moiseev, Nikolai Bulanov, Victor Fomin Tags: Letter to the Editor Source Type: research
A Young Woman With A History of Stroke and Recurrent Migraine Headaches
A 34-year-old woman with a history of recurrent migraine without aura headaches, right pontine stroke, and recurrent small vessel subcortical infarcts presented to the emergency department with complaints of intermittent blurry vision and worsening headache. Magnetic resonance imaging of the brain was performed (Figure 1). Three 4-mm punch biopsies were performed on the normal skin of the right upper extremity, and a blood sample was submitted for NOTCH3 (notch receptor 3) genetic testing. Electron microscopy revealed the presence of granular osmiophilic material in the basement membrane of capillary smooth musc le cells...
Source: Mayo Clinic Proceedings - May 31, 2019 Category: Internal Medicine Authors: Emily Carr, Lana Joudeh Tags: Medical image Source Type: research
Left Atrial Appendage Occlusion for The Unmet Clinical Needs of Stroke Prevention in Nonvalvular Atrial Fibrillation
Oral anticoagulation is the dominant strategy for stroke prevention in patients with nonvalvular atrial fibrillation. However, lifelong oral anticoagulation is associated with major issues including inappropriate dosing, nonadherence, and adverse effects. Therefore, efforts have been made to develop site-specific therapy aimed to occlude the left atrial appendage, the anatomical site accountable for more than 90% of nonvalvular atrial fibrillation –related ischemic strokes. This review focuses on the growing literature to put into perspective the risk-balance ratio of left atrial appendage occlusion.
Source: Mayo Clinic Proceedings - April 4, 2019 Category: Internal Medicine Authors: David R. Holmes, Mohamad Alkhouli, Vivek Reddy Tags: Review Source Type: research
Analysis of Vascular Event Risk After Herpes Zoster From 2007 to 2014 US Insurance Claims Data
To estimate the risk of transient ischemic attack (TIA), stroke, and myocardial infarction in periods covering 4 weeks before to 52 weeks after herpes zoster (HZ) diagnosis in US adults.
Source: Mayo Clinic Proceedings - April 3, 2019 Category: Internal Medicine Authors: Brandon J. Patterson, Debora A. Rausch, Debra E. Irwin, Michael Liang, Songkai Yan, Barbara P. Yawn Tags: Original article Source Type: research
Low-Sodium Intake: A Risk Factor for Stroke?
The recent findings by Kieneker et al1 represent the first convincing evidence that a low sodium intake might be linked to an increased cerebrovascular risk. The highly cited papers by a Canadian group2 already claimed to show a sort of J-shaped association between sodium intake and cardiovascular events, but there are limitations to these studies, as has been discussed previously.3
Source: Mayo Clinic Proceedings - March 31, 2019 Category: Internal Medicine Authors: Natale Musso, Andrea Dotto Tags: Letter to the Editor Source Type: research
In reply —Low-Sodium Intake: A Risk Factor for Stroke?
We are grateful to Drs Musso and Dotto1 for the appraisal of our article on low urinary sodium excretion (UNaV) as an indicator of low sodium intake and increased risk of stroke.2 We agree that the mentioned earlier study by O ’Donnell and colleagues,3 although representative of various populations by including more than 100,000 participants from 17 countries, has some limitations. In particular, the assessment of sodium intake via a single spot urine sample is a major limitation. Actual measurement of 24-hour UNaV in m ultiple urine collections (to account for day-to-day variability), as we did in the Prevention of Rena...
Source: Mayo Clinic Proceedings - March 31, 2019 Category: Internal Medicine Authors: Lyanne M. Kieneker, Michele F. Eisenga, Stephan J.L. Bakker Tags: Letter to the Editor Source Type: research
In reply —Sauna Bathing and Healthy Sweating
We thank Eiser and Brooks for their comments about the health benefits of sauna bathing. Regular sauna bathing has some beneficial effects on blood pressure, cardiometabolic biomarkers, arterial compliance, and cardiovascular function.1 Our prospective studies have shown that higher frequency and duration of sauna bathing are related to a lower risk of cardiovascular mortality, sudden cardiac death, stroke, hypertension, pulmonary diseases, and dementia.1-3 The feelings of relaxation and promotion of mental health and well-being associated with sauna sessions might be linked to the increased production of circulating level...
Source: Mayo Clinic Proceedings - March 31, 2019 Category: Internal Medicine Authors: Jari A. Laukkanen, Tanjaniina Laukkanen, Setor Kunutsor Tags: Letter to the Editor Source Type: research
Perception of the Risk of Stroke and the Risks and Benefits of Oral Anticoagulation for Stroke Prevention in Patients With Atrial Fibrillation: A Cross-Sectional Study
To assess the perception of the risk of stroke and the risks and benefits of oral anticoagulation (OAC) in patients with atrial fibrillation (AF).
Source: Mayo Clinic Proceedings - March 28, 2019 Category: Internal Medicine Authors: Mohammad Hijazi, Sami Aljohani, Fahad Alqahtani, Zakeih Chaker, Muhammad Al Hajji, Ahmad Al Hallak, Mohamad Alkhouli Tags: Original article Source Type: research
White Matter Hyperintensities on Magnetic Resonance Imaging: What Is a Clinician to Do?
As a neurologist, I am often asked to see patients because they have a magnetic resonance image (MRI) of the brain showing white matter hyperintensities (WMHs). These patients, and the clinicians who refer them to me, want to know the answers to several questions: What are WMHs and what causes them? Are they the same as a stroke? Are they a marker for impending stroke, dementia, or death? Do they get worse over time and can the progression be slowed? Studies such as the one by Hasan et al1 in this issue of Mayo Clinic Proceedings have expanded our understanding of the etiology and clinical significance of WMHs.
Source: Mayo Clinic Proceedings - March 1, 2019 Category: Internal Medicine Authors: Jos é G. Merino Tags: Editorial Source Type: research
Weight and Risk of Incident Atrial Fibrillation —Body Mass Index Variability or Body Mass Gain?
Atrial fibrillation (AF) is an emerging global epidemic associated with significant morbidity and mortality. In recent decades, AF prevalence has exponentially risen and is showing no sign of abating. The condition is associated with numerous complications including stroke, heart failure, and all-cause mortality —risks that are evident even in individuals with few comorbidites.1,2 In the Asia-Pacific region, although AF prevalence is lower than that in Western countries, total AF burden is much higher in this region, in part because of larger populations and rising levels of modifiable cardiovascular risk factors.
Source: Mayo Clinic Proceedings - January 31, 2019 Category: Internal Medicine Authors: Celine Gallagher, Melissa E. Middeldorp, Prashanthan Sanders Tags: Editorial Source Type: research
Retinal Occlusion, Ischemic Stroke, and the Brain-Eye Connection
The risk of cerebral infarction associated with retinal ischemia has been the subject of an evolving debate. Several factors complicate this association, including varied types of ischemic visual events ranging from transient monocular visual loss to anterior ischemic optic neuropathy and retinal artery occlusion (branch or central); additionally, diagnostic and therapeutic options for cerebral ischemia continue to advance.
Source: Mayo Clinic Proceedings - January 31, 2019 Category: Internal Medicine Authors: Eric R. Eggenberger Tags: Editorial Source Type: research
Body Mass Index Variability and Long-term Risk of New-Onset Atrial Fibrillation in the General Population: A Korean Nationwide Cohort Study
To assess the effects of body mass index (BMI) variability on the incidence of new-onset atrial fibrillation (AF), stroke, cardiovascular (CV) risk factors, and CV outcomes in a general Asian population.
Source: Mayo Clinic Proceedings - January 31, 2019 Category: Internal Medicine Authors: Yeong-Min Lim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip Tags: Original article Source Type: research
