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Specialty: Internal Medicine
Source: Annals of Internal Medicine

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Total 404 results found since Jan 2013.

First-Line Therapy for Type 2 Diabetes With Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists : A Cost-Effectiveness Study
CONCLUSION: As first-line agents, SGLT2 inhibitors and GLP1 receptor agonists would improve type 2 diabetes outcomes, but their costs would need to fall by at least 70% to be cost-effective.PRIMARY FUNDING SOURCE: American Diabetes Association.PMID:36191315 | DOI:10.7326/M21-2941
Source: Annals of Internal Medicine - October 3, 2022 Category: Internal Medicine Authors: Jin G Choi Aaron N Winn M Reza Skandari Melissa I Franco Erin M Staab Jason Alexander Wen Wan Mengqi Zhu Elbert S Huang Louis Philipson Neda Laiteerapong Source Type: research

In ischemic stroke, IV alteplase within 3 h of onset improves functional outcome vs. control
Ann Intern Med. 2022 Sep 6. doi: 10.7326/J22-0069. Online ahead of print.ABSTRACTMun KT, Bonomo JB, Liebeskind DS, et al. Fragility index meta-analysis of randomized controlled trials shows highly robust evidential strength for benefit of < 3 hour intravenous alteplase. Stroke. 2022;53:2069-74. 35543129.PMID:36063553 | DOI:10.7326/J22-0069
Source: Annals of Internal Medicine - September 5, 2022 Category: Internal Medicine Authors: Barnet Eskin Source Type: research

Early Rhythm Control Therapy for Atrial Fibrillation in Low-Risk Patients : A Nationwide Propensity Score-Weighted Study
CONCLUSION: In routine clinical practice, the beneficial association between early rhythm control and cardiovascular complications was consistent among low-risk patients regardless of trial eligibility.PRIMARY FUNDING SOURCE: The Ministry of Health and Welfare and the Ministry of Food and Drug Safety, Republic of Korea.PMID:36063552 | DOI:10.7326/M21-4798
Source: Annals of Internal Medicine - September 5, 2022 Category: Internal Medicine Authors: Daehoon Kim Pil-Sung Yang Seng Chan You Eunsun Jang Hee Tae Yu Tae-Hoon Kim Hui-Nam Pak Moon-Hyoung Lee Gregory Y H Lip Jung-Hoon Sung Boyoung Joung Source Type: research

In ischemic stroke, IV alteplase within 3 h of onset improves functional outcome vs. control
Ann Intern Med. 2022 Sep 6. doi: 10.7326/J22-0069. Online ahead of print.ABSTRACTMun KT, Bonomo JB, Liebeskind DS, et al. Fragility index meta-analysis of randomized controlled trials shows highly robust evidential strength for benefit of < 3 hour intravenous alteplase. Stroke. 2022;53:2069-74. 35543129.PMID:36063553 | DOI:10.7326/J22-0069
Source: Annals of Internal Medicine - September 5, 2022 Category: Internal Medicine Authors: Barnet Eskin Source Type: research

Early Rhythm Control Therapy for Atrial Fibrillation in Low-Risk Patients : A Nationwide Propensity Score-Weighted Study
CONCLUSION: In routine clinical practice, the beneficial association between early rhythm control and cardiovascular complications was consistent among low-risk patients regardless of trial eligibility.PRIMARY FUNDING SOURCE: The Ministry of Health and Welfare and the Ministry of Food and Drug Safety, Republic of Korea.PMID:36063552 | DOI:10.7326/M21-4798
Source: Annals of Internal Medicine - September 5, 2022 Category: Internal Medicine Authors: Daehoon Kim Pil-Sung Yang Seng Chan You Eunsun Jang Hee Tae Yu Tae-Hoon Kim Hui-Nam Pak Moon-Hyoung Lee Gregory Y H Lip Jung-Hoon Sung Boyoung Joung Source Type: research

Tea Consumption and All-Cause and Cause-Specific Mortality in the UK Biobank : A Prospective Cohort Study
CONCLUSION: Higher tea intake was associated with lower mortality risk among those drinking 2 or more cups per day, regardless of genetic variation in caffeine metabolism. These findings suggest that tea, even at higher levels of intake, can be part of a healthy diet.PRIMARY FUNDING SOURCE: National Cancer Institute Intramural Research Program.PMID:36037472 | DOI:10.7326/M22-0041
Source: Annals of Internal Medicine - August 29, 2022 Category: Internal Medicine Authors: Maki Inoue-Choi Yesenia Ramirez Marilyn C Cornelis Amy Berrington de Gonz ález Neal D Freedman Erikka Loftfield Source Type: research

Risk for Myocardial Infarction, Stroke, and Pulmonary Embolism Following COVID-19 Vaccines in Adults Younger Than 75 Years in France
CONCLUSION: In persons aged 18 to 74 years, adenoviral-based vaccines may be associated with increased incidence of MI and PE. No association between mRNA-based vaccines and the cardiovascular events studied was observed.PRIMARY FUNDING SOURCE: None.PMID:35994748 | DOI:10.7326/M22-0988
Source: Annals of Internal Medicine - August 22, 2022 Category: Internal Medicine Authors: J érémie Botton Marie Joelle Jabagi Marion Bertrand B érangère Baricault J érôme Drouin St éphane Le Vu Alain Weill Paddy Farrington Mahmoud Zureik Rosemary Dray-Spira Source Type: research