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Specialty: Internal Medicine
Source: Annals of Internal Medicine

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Total 404 results found since Jan 2013.

In ischemic stroke upon wakening, IV thrombolysis or EVT improves functional outcome at 90 d
Ann Intern Med. 2022 Apr 5. doi: 10.7326/J22-0020. Online ahead of print.ABSTRACTRoaldsen MB, Lindekleiv H, Mathiesen EB. Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke. Cochrane Database Syst Rev. 2021;12:CD010995. 34850380.PMID:35377725 | DOI:10.7326/J22-0020
Source: Annals of Internal Medicine - April 4, 2022 Category: Internal Medicine Authors: Katie Lin Eddy Lang Source Type: research

In acute ischemic stroke, EVT alone vs. IV alteplase plus EVT did not differ for functional outcome at 90 d
Ann Intern Med. 2022 Apr 5. doi: 10.7326/J22-0016. Online ahead of print.ABSTRACTLeCouffe NE, Kappelhof M, Treurniet KM, et al. A randomized trial of intravenous alteplase before endovascular treatment for stroke. N Engl J Med. 2021;385:1833-44. 34758251.PMID:35377718 | DOI:10.7326/J22-0016
Source: Annals of Internal Medicine - April 4, 2022 Category: Internal Medicine Authors: Barnet Eskin Source Type: research

In patients with stroke or TIA and CYP2C19 loss-of-function alleles, ticagrelor vs. clopidogrel reduced 90-d stroke
Ann Intern Med. 2022 Mar 1. doi: 10.7326/J22-0008. Online ahead of print.ABSTRACTWang Y, Meng X, Wang A, et al. Ticagrelor versus clopidogrel in CYP2C19 loss-of-function carriers with stroke or TIA. N Engl J Med. 2021;385:2520-30. 34708996.PMID:35226525 | DOI:10.7326/J22-0008
Source: Annals of Internal Medicine - February 28, 2022 Category: Internal Medicine Authors: Raed A Joundi Source Type: research

Case Series of Thrombosis With Thrombocytopenia Syndrome After COVID-19 Vaccination-United States, December 2020 to August 2021
CONCLUSION: Thrombosis with thrombocytopenia syndrome is a rare but serious adverse event associated with Ad26.COV2.S vaccination. The different demographic characteristics of the 3 cases reported after mRNA-based COVID-19 vaccines and the much lower reporting rate suggest that these cases represent a background rate.PRIMARY FUNDING SOURCE: Centers for Disease Control and Prevention.PMID:35038274 | DOI:10.7326/M21-4502
Source: Annals of Internal Medicine - January 17, 2022 Category: Internal Medicine Authors: Isaac See Allison Lale Paige Marquez Michael B Streiff Allison P Wheeler Naomi K Tepper Emily Jane Woo Karen R Broder Kathryn M Edwards Ruth Gallego Andrew I Geller Kelly A Jackson Shashi Sharma Kawsar R Talaat Emmanuel B Walter Imo J Akpan Thomas L Ortel Source Type: research

In older patients at high risk for stroke, intensive AF screening with an implantable loop recorder did not reduce stroke
Ann Intern Med. 2022 Jan 4. doi: 10.7326/J21-0011. Online ahead of print.ABSTRACTSvendsen JH, Diederichsen SZ, HĂžjberg S, et al. Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial. Lancet. 2021;398:1507-16. 34469766.PMID:34978859 | DOI:10.7326/J21-0011
Source: Annals of Internal Medicine - January 3, 2022 Category: Internal Medicine Authors: Mohammed Yousufuddin Arshad Jahangir Source Type: research

Associations of Serum Testosterone and Sex Hormone-Binding Globulin With Incident Cardiovascular Events in Middle-Aged to Older Men
CONCLUSION: Men with lower total testosterone concentrations were not at increased risk for MI, stroke, HF, or MACE. Calculated free testosterone may be associated with risk for MACE. Men with lower SHBG concentrations have higher risk for MI but lower risk for IS and HF, with causality to be determined.PRIMARY FUNDING SOURCE: Western Australian Health Translation Network, Medical Research Future Fund, and Lawley Pharmaceuticals.PMID:34958606 | DOI:10.7326/M21-0551
Source: Annals of Internal Medicine - December 27, 2021 Category: Internal Medicine Authors: Bu B Yeap Ross J Marriott Leen Antonio Suchitra Raj Girish Dwivedi Christopher M Reid Bradley D Anawalt Shalender Bhasin Adrian S Dobs David J Handelsman Graeme J Hankey Robin Haring Alvin M Matsumoto Paul E Norman Terence W O'Neill Claes Ohlsson Eric S O Source Type: research