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The effect of a locally adapted, secondary stroke risk factor self-management program on medication adherence among veterans with stroke/TIA
Abstract We targeted stroke/transient ischemic attack (TIA) survivors to engage in self-management practices to manage secondary stroke risk factors. We conducted a randomized, regional pilot trial of a locally adapted, secondary stroke prevention program. We implemented the program at two Veterans Administration Medical Centers. Program sessions targeted stroke risk factor self-management. Specifically, we evaluated the effect of the program on the reach, implementation, and effectiveness on patient self-efficacy; stroke-specific, health-related quality of life; and medication adherence for the prevalent stroke r...
Source: Translational Behavioral Medicine - October 26, 2015 Category: Global & Universal Source Type: research

Opportunities for intervention: stroke treatments, disability and mortality in urban Tanzania
ConclusionsThe 90-day mortality of stroke presenting at MNH is 50%, much higher than in higher income settings. Although severe stroke presentations are a major factor, efforts to improve the quality of care and prevent complications of stroke are urgently needed. Acute stroke interventions with low number needed to treat represent challenging long-term goals.
Source: International Journal for Quality in Health Care - August 28, 2018 Category: International Medicine & Public Health Source Type: research

Processes and outcomes of ischemic stroke care: the influence of hospital level of care
Conclusions Outcomes among patients with ischemic stroke can be improved by thrombolytic therapy, antithrombotic therapy, statin treatment and rehabilitation assessment. Among patients with ischemic stroke, admission to designated stroke center hospitals may be associated with lower mortality through better processes of care.
Source: International Journal for Quality in Health Care - July 31, 2015 Category: Global & Universal Authors: Tung, Y.-C., Jeng, J.-S., Chang, G.-M., Chung, K.-P. Tags: Papers Source Type: research

Use of aspirin and statins for the primary prevention of myocardial infarction and stroke in patients with human immunodeficiency virus infection
This retrospective, cross-sectional study evaluated whether HIV-infected patients received aspirin and statins for the primary prevention of myocardial infarction and stroke. Among the 258 patients included, 50.4% (n = 130/258) of the patients had a high risk of myocardial infarction and 14% (n = 36/258) of stroke. Overall, 43.1% (n = 56/130) and 50% (n = 18/36) of the patients were prescribed aspirin for the primary prevention of myocardial infarction and stroke, respectively. Among the patients who required statin therapy, 42.5% (n = 34/80) and 37.1% (n = 13/35) of patients received it for the primary prevention of myoca...
Source: International Journal of STD and AIDS - April 6, 2016 Category: Global & Universal Authors: Park, T. E., Yusuff, J., Sharma, R. Tags: Original research articles Source Type: research

Anti-inflammatory and anti-thrombogenic effects of atorvastatin in acute ischemic stroke
(Neural Regeneration Research) A recent study by Lianqiu Min and colleagues from Liaoning Medical University observed the effects of atorvastatin treatment in 89 patients from northeastern China with acute ischemic stroke caused by intracranial large-artery atherosclerosis by measuring changes in the levels of markers of inflammation, thrombogenesis, and hyperlipidemia.
Source: EurekAlert! - Medicine and Health - September 10, 2013 Category: Global & Universal Source Type: news

Statin drugs reduce infection risk in stroke patients
(Washington State University) A Washington State University researcher has found that statin drugs can dramatically lower the risk of infections in stroke patients.
Source: EurekAlert! - Medicine and Health - June 16, 2016 Category: Global & Universal Source Type: news

Concerns over side effects of statins stopping stroke survivors taking medication
(University of Cambridge) Negative media coverage of the side effects associated with taking statins, and patients' own experiences of taking the drugs, are among the reasons cited by stroke survivors and their carers for stopping taking potentially life-saving drugs, according to research published today.
Source: EurekAlert! - Medicine and Health - July 16, 2017 Category: International Medicine & Public Health Source Type: news

Heart attack and stroke patients prescribed statin medication upon discharge have better outcomes
(Intermountain Medical Center) Patients with a prior history of heart attacks or stroke have better outcomes when cholesterol-lowering medications are used after they're discharged from the hospital, according to a new study from the Intermountain Medical Center Heart Institute in Salt Lake City.
Source: EurekAlert! - Medicine and Health - November 12, 2017 Category: International Medicine & Public Health Source Type: news

Statin use reduces mortality and stroke risk in dementia patients, new study shows
(Spink Health) The study, which analyzed 44,920 Swedish dementia patients from the Swedish Dementia Registry between 2008-2015, found users of statins had a 22% lower risk of all-cause death compared to matched non-users. The research also demonstrated that statin users had a 23% reduction in the risk of stroke, which is three times more likely in patients with mild dementia and seven times more likely in those with severe dementia.
Source: EurekAlert! - Medicine and Health - June 30, 2019 Category: International Medicine & Public Health Source Type: news

Markov Model-Based Economic Evaluation of Combination Therapy with Ezetimibe and Statin Monotherapy
The iCaPPS was designed to deliver comprehensive post stroke care for stroke survivors in communities with limited access to specialised stroke care services. Rehabilitation intervention and regular screening for post stroke complications were additional features of iCaPPS compared with conventional care practices.
Source: Value in Health - November 1, 2014 Category: Global & Universal Authors: D Pan Source Type: research

Atorvastatin-meloxicam association inhibits neuroinflammation and attenuates the cellular damage in cerebral ischemia by arterial embolism.
CONCLUSION: These results suggest that the meloxicam-atorvastatin association attenuates astrocytic and microglial response in the inflammatory process after cerebral ischemia by arterial embolism, reducing neurodegeneration and restoring the morphological and functional balance of nervous tissue . PMID: 25504124 [PubMed - indexed for MEDLINE]
Source: Biomedica : Revista del Instituto Nacional de Salud - November 28, 2015 Category: Global & Universal Tags: Biomedica Source Type: research

Statins can save lives, are they being used?
(Mayo Clinic) People who have coronary artery disease, stroke or peripheral artery disease often are prescribed a statin, a cholesterol-lowering drug that reduces the risk of heart attack or stroke.
Source: EurekAlert! - Medicine and Health - December 1, 2020 Category: International Medicine & Public Health Source Type: news

New cholesterol medication guidelines
The American College of Cardiology and the American Heart Association recently released new guidelines that could lead to many healthy Americans taking cholesterol-lowering statin medications. Statins not only lower LDL, or "bad," cholesterol, they also prevent the incidence of heart attacks and stroke. Eric Topol, M.D., discusses the new guidelines and the potential pitfalls of over-prescribing s....
Source: Sound Medicine - December 7, 2013 Category: Global & Universal Authors: Sound Medicine Source Type: news

Report urges individualized, cholesterol-targeted approach to heart disease and stroke
(Oregon State University) A recent guideline for using statins to reduce atherosclerotic cardiovascular disease has wavered too far from the simple cholesterol goals that have saved thousands of lives in the past decade, and doesn't adequately treat patients as individuals, experts said today in a national report.
Source: EurekAlert! - Medicine and Health - September 15, 2014 Category: Global & Universal Source Type: news

NIH-led study explores prevention of heart disease in HIV-infected people
(NIH/National Institute of Allergy and Infectious Diseases) The National Institutes of Health has launched a clinical trial to assess the effects of aspirin and cholesterol-lowering drugs, or statins, on preventing cardiovascular disease in people with long-term HIV infections. This group, which includes people on antiretroviral therapy as well as 'elite controllers' who can limit the virus without antiretroviral therapy, have a higher risk of developing heart disease and stroke compared to the general population.
Source: EurekAlert! - Medicine and Health - October 28, 2014 Category: Global & Universal Source Type: news

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