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Specialty: Neurology
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Interpretable machine learning for prediction of clinical outcomes in acute ischemic stroke
ConclusionML algorithms demonstrated proficient prediction for the 3-month functional outcome in AIS patients. With the aid of the SHAP method, we can attain an in-depth understanding of how critical features contribute to model predictions and how changes in these features influence such predictions.
Source: Frontiers in Neurology - September 7, 2023 Category: Neurology Source Type: research
Post-stroke Headache
AbstractPurpose of ReviewStroke is a major health concern and a leading cause of long-term disability. Persistent post-stroke headache (PPSH) is a common complication of stroke yet little is known about its specific characteristics or optimal management. The purpose of this review is to discuss the epidemiology, presentation, and hypothesized pathophysiology of PPSH. Acute and preventive treatment options, as well as specific concerns regarding triptans and the newer CGRP antagonists, will be discussed in detail as well.Recent FindingsThe 2018 International Classification of Headache Disorders, 3rd edition (ICHD-3) was the...
Source: Current Pain and Headache Reports - September 7, 2023 Category: Neurology Source Type: research
Treatment of In-stent Restenosis of the Internal Carotid Artery Using Drug-eluting Balloons
ConclusionThe use of DEB angioplasty is a safe and effective treatment of ICA ISR lesions, yielding significantly better results compared to other modalities. Randomized multicenter studies are warranted.
Source: Clinical Neuroradiology - September 7, 2023 Category: Neurology Source Type: research
Applicability of the low-grade inflammation score in predicting 90-day functional outcomes after acute ischemic stroke
The low-grade inflammation (LGI) score, a novel indicator of chronic LGI, combines C-reactive protein (CRP), leukocyte counts, the neutrophil/lymphocyte ratio (NLR), and the platelet (PLT) count to predict out...
Source: BMC Neurology - September 7, 2023 Category: Neurology Authors: Yang Zhou, Yufan Luo, Huazheng Liang, Ping Zhong and Danhong Wu Tags: Research Source Type: research
Impact of e-ASPECTS software on the performance of physicians compared to a consensus ground truth: a multi-reader, multi-case study
ConclusionDecision support with the e-ASPECTS software significantly improves the accuracy of ASPECTS scoring, even by expert US neurologists and neuroradiologists.
Source: Frontiers in Neurology - September 7, 2023 Category: Neurology Source Type: research
The experiences of young women living post-stroke in Jordan: a descriptive phenomenological study
CONCLUSION: After their stroke, Jordanian women have experienced profound, interrelated, and multifaceted difficulties in all aspects of their life and relationships inside and outside the family. Whilst healthcare providers recognize these stressful symptoms; however, there is a lack of attention and care to meet these needs.PMID:37671993 | DOI:10.1080/10749357.2023.2254049
Source: Topics in Stroke Rehabilitation - September 6, 2023 Category: Neurology Authors: Marwa Nayef Alhalabi Inaam Abdallah Khalaf Ruqayya Sayed Zeilani Hala Ahmad Bawadi Ahmad S Musa Abdulqadir J Nashwan Source Type: research
Do we need to consider head-on-body position, starting roll position and presence of visuospatial neglect when assessing perception of verticality after stroke?
CONCLUSIONS: HOB position and the presence of SRP and VSN are important factors to consider during SVV and SPV measurements. Assessment with a neutral HOB position leads to more accurate results. HOB position and SRP influence the results of SVV and SPV differently in individuals with and without VSN, which highlights the relevance of VSN assessment.PMID:37671676 | DOI:10.1080/10749357.2023.2253622
Source: Topics in Stroke Rehabilitation - September 6, 2023 Category: Neurology Authors: Charlotte van der Waal Elissa Embrechts Steven Truijen Wim Saeys Source Type: research
Phenothiazines reduced autophagy in ischemic stroke through endoplasmic reticulum (ER) stress-associated PERK-eIF2 α pathway
CONCLUSION: The combined treatment of C + P plays a crucial role in stroke therapy by inhibiting ER stress-mediated autophagy, thereby leading to reduced apoptosis and increased neuroprotection. Our findings highlight the PERK-eIF2α pathway as a central mechanism through which C + P exerts its beneficial effects. The results from this study may pave the way for the development of more targeted and effective treatments for stroke patients.PMID:37673390 | DOI:10.1016/j.expneurol.2023.114524
Source: Experimental Neurology - September 6, 2023 Category: Neurology Authors: Shuyu Lv Xiaokun Geng Ho Jun Yun Yuchuan Ding Source Type: research
The experiences of young women living post-stroke in Jordan: a descriptive phenomenological study
CONCLUSION: After their stroke, Jordanian women have experienced profound, interrelated, and multifaceted difficulties in all aspects of their life and relationships inside and outside the family. Whilst healthcare providers recognize these stressful symptoms; however, there is a lack of attention and care to meet these needs.PMID:37671993 | DOI:10.1080/10749357.2023.2254049
Source: Topics in Stroke Rehabilitation - September 6, 2023 Category: Neurology Authors: Marwa Nayef Alhalabi Inaam Abdallah Khalaf Ruqayya Sayed Zeilani Hala Ahmad Bawadi Ahmad S Musa Abdulqadir J Nashwan Source Type: research
Do we need to consider head-on-body position, starting roll position and presence of visuospatial neglect when assessing perception of verticality after stroke?
CONCLUSIONS: HOB position and the presence of SRP and VSN are important factors to consider during SVV and SPV measurements. Assessment with a neutral HOB position leads to more accurate results. HOB position and SRP influence the results of SVV and SPV differently in individuals with and without VSN, which highlights the relevance of VSN assessment.PMID:37671676 | DOI:10.1080/10749357.2023.2253622
Source: Topics in Stroke Rehabilitation - September 6, 2023 Category: Neurology Authors: Charlotte van der Waal Elissa Embrechts Steven Truijen Wim Saeys Source Type: research
The experiences of young women living post-stroke in Jordan: a descriptive phenomenological study
CONCLUSION: After their stroke, Jordanian women have experienced profound, interrelated, and multifaceted difficulties in all aspects of their life and relationships inside and outside the family. Whilst healthcare providers recognize these stressful symptoms; however, there is a lack of attention and care to meet these needs.PMID:37671993 | DOI:10.1080/10749357.2023.2254049
Source: Topics in Stroke Rehabilitation - September 6, 2023 Category: Neurology Authors: Marwa Nayef Alhalabi Inaam Abdallah Khalaf Ruqayya Sayed Zeilani Hala Ahmad Bawadi Ahmad S Musa Abdulqadir J Nashwan Source Type: research
Do we need to consider head-on-body position, starting roll position and presence of visuospatial neglect when assessing perception of verticality after stroke?
CONCLUSIONS: HOB position and the presence of SRP and VSN are important factors to consider during SVV and SPV measurements. Assessment with a neutral HOB position leads to more accurate results. HOB position and SRP influence the results of SVV and SPV differently in individuals with and without VSN, which highlights the relevance of VSN assessment.PMID:37671676 | DOI:10.1080/10749357.2023.2253622
Source: Topics in Stroke Rehabilitation - September 6, 2023 Category: Neurology Authors: Charlotte van der Waal Elissa Embrechts Steven Truijen Wim Saeys Source Type: research
Phenothiazines reduced autophagy in ischemic stroke through endoplasmic reticulum (ER) stress-associated PERK-eIF2 α pathway
CONCLUSION: The combined treatment of C + P plays a crucial role in stroke therapy by inhibiting ER stress-mediated autophagy, thereby leading to reduced apoptosis and increased neuroprotection. Our findings highlight the PERK-eIF2α pathway as a central mechanism through which C + P exerts its beneficial effects. The results from this study may pave the way for the development of more targeted and effective treatments for stroke patients.PMID:37673390 | DOI:10.1016/j.expneurol.2023.114524
Source: Experimental Neurology - September 6, 2023 Category: Neurology Authors: Shuyu Lv Xiaokun Geng Ho Jun Yun Yuchuan Ding Source Type: research
The experiences of young women living post-stroke in Jordan: a descriptive phenomenological study
CONCLUSION: After their stroke, Jordanian women have experienced profound, interrelated, and multifaceted difficulties in all aspects of their life and relationships inside and outside the family. Whilst healthcare providers recognize these stressful symptoms; however, there is a lack of attention and care to meet these needs.PMID:37671993 | DOI:10.1080/10749357.2023.2254049
Source: Topics in Stroke Rehabilitation - September 6, 2023 Category: Neurology Authors: Marwa Nayef Alhalabi Inaam Abdallah Khalaf Ruqayya Sayed Zeilani Hala Ahmad Bawadi Ahmad S Musa Abdulqadir J Nashwan Source Type: research
Phenothiazines reduced autophagy in ischemic stroke through endoplasmic reticulum (ER) stress-associated PERK-eIF2 α pathway
CONCLUSION: The combined treatment of C + P plays a crucial role in stroke therapy by inhibiting ER stress-mediated autophagy, thereby leading to reduced apoptosis and increased neuroprotection. Our findings highlight the PERK-eIF2α pathway as a central mechanism through which C + P exerts its beneficial effects. The results from this study may pave the way for the development of more targeted and effective treatments for stroke patients.PMID:37673390 | DOI:10.1016/j.expneurol.2023.114524
Source: Experimental Neurology - September 6, 2023 Category: Neurology Authors: Shuyu Lv Xiaokun Geng Ho Jun Yun Yuchuan Ding Source Type: research
