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Craniovertebral Junction Anomalies: An Overlooked Cause of & #39;Posterior Circulation Stroke & #39;
Conclusions: CVJ anomalies can present as posterior circulation infarct. One must evaluate all patients with posterior circulation stroke, especially young patients, for possible CVJ anomalies. Dynamic lateral cervical spine X-ray is an important tool to diagnose AAD. CVJ anomalies represent a treatable cause of VAD.
Source: Neurology India - November 11, 2022 Category: Neurology Authors: Kanwaljeet Garg Vivek Tandon Rajinder Kumar P Sarat Chandra Shashank S Kale Bhawani Shankar Sharma Ashok K Mahapatra Source Type: research

Effect of Age, Stage, and Type of Surgical Revascularization on Clinical and Angiographic Outcome in Moyamoya Disease & #8211; Experience from a Case Series of 175 Revascularization Procedures
Conclusions: In pediatrics, clinical and angiographic outcome significantly improved after revascularization procedure, and in adults, angiographic improvement was more evident than clinical recovery. Late-stage Suzuki MMD patients demonstrated significantly better clinical improvement than early stage. The angiographic improvement was equivalent to early stage, irrespective of age and type of revascularization.
Source: Neurology India - October 21, 2022 Category: Neurology Authors: Sanjeev A Sreenivasan Ashish Suri Amol Raheja Subhash Phuyal Manmohan Singh Shashwat Mishra Vivek Tandon Leve J Devarajan1 M Kalaivani Sarat C Poodipedi Shashank S Kale Source Type: research

Prognostic Significance of Fragmented QRS in Patients with Acute Ischemic Stroke
Stroke is a leading cause of mortality and morbidity in developed countries1 and has a strong relationship with cardiovascular system disorders.2 Due to this relationship, the connection between brain and heart has become increasingly important and neurocardiology has emerged as a popular concept over the recent years.3 Electrocardiographic abnormalities and various cardiac arrhythmias occurring especially after stroke support this phenomenon.4 ST segment and/or T-wave abnormalities without myocardial ischemia,5 left axis deviation, QT prolongation,6 QT dispersion,7 atrial fibrillation (AF), sinus tachycardia, ventricular ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 14, 2021 Category: Neurology Authors: Irfan Sahin, Orkhan Karimov, Adem Atici, Hasan Ali Barman, Sevil Tugrul, Sevgi Ozcan, Ramazan Asoglu, Didem Celik, Ertugrul Okuyan, Nilufer Kale Source Type: research

Protocatechuic Acid Prevents Early Hour Ischemic Reperfusion Brain Damage by Restoring Imbalance of Neuronal Cell Death and Survival Proteins
Objective: To investigate the neuroprotective effect of protocatechuic acid (PCA) on cell death/survival protein imbalance in a rat model of middle cerebral artery occlusion and reperfusion. Methods: Focal ischemia was induced by middle cerebral artery occlusion in adult male Wistar rats and confirmed by measuring infarction of brain by 2,3,5-Triphenyltetrazolium chloride (TTC) staining. Rats were treated with vehicle or PCA at 10, 30 or 50 mg/kg dose intraperitoneally and subjected to neurological deficits or beam walk assessment at 24 h of reperfusion.
Source: Journal of Stroke and Cerebrovascular Diseases - December 4, 2020 Category: Neurology Authors: Swapnil Kale, Lopmudra P. Sarode, Amol Kharat, Saurabh Ambulkar, Anand Prakash, Amul J. Sakharkar, Rajesh R. Ugale Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative TCD Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Stroke Due to Air Embolism Related to Laser Ablation of Accessory Vein (P4.357)
Conclusions: Air embolism leading to devastating stroke may occur few hours after laser treatment of varicose veins. Chest symptoms associated with the procedure should raise the possibility of air embolism. Immediate therapeutic measures like 100[percnt] oxygen, hyperbaric oxygen chamber and/or hypothermia should be considered to prevent neurologic complications.Disclosure: Dr. Kale has nothing to disclose. Dr. Javed has nothing to disclose. Dr. Pednekar has nothing to disclose. Dr. Sahni has nothing to disclose. Dr. Resor has nothing to disclose. Dr. Tenner has nothing to disclose. Dr. Ahluwalia-Singh has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kale, P., Javed, B., Pednekar, N., Sahni, R., Resor, L., Tenner, M., Ahluwalia-Singh, B. Tags: Cerebrovascular Case Reports Source Type: research

Outcome after decompressive craniectomy in patients with dominant middle cerebral artery infarction: A preliminary report
Conclusion: Language and motor outcomes after DC in patients with DMCAI are not as dismal as commonly perceived. Perhaps young patients (<50 years) with DMCAI should be treated with the same aggressiveness that non-DMCAI is currently dealt with.
Source: Annals of Indian Academy of Neurology - October 25, 2013 Category: Neurology Authors: Amandeep KumarManish Singh SharmaBhawani Shanker SharmaRohit BhatiaManmohan SinghAjay GargRajinder KumarAshish SuriPoodipedi Sarat ChandraShashank Sharad KaleAshok Kumar Mahapatra Source Type: research